STRINGSTRING
PCK2 PCK2 AKT1 AKT1 IKBKG IKBKG ACSL3 ACSL3 PPARGC1A PPARGC1A RELA RELA MAPK8 MAPK8 PRKAB2 PRKAB2 G6PC G6PC ADIPOR2 ADIPOR2 TNF TNF RXRG RXRG G6PC3 G6PC3 STK11 STK11 CD36 CD36 ACSL6 ACSL6 SOCS3 SOCS3 SLC2A4 SLC2A4 MAPK9 MAPK9 TNFRSF1A TNFRSF1A CPT1C CPT1C JAK2 JAK2 PRKAG2 PRKAG2 CPT1B CPT1B NFKBIE NFKBIE ADIPOQ ADIPOQ NFKBIB NFKBIB PRKAG3 PRKAG3 PTPN11 PTPN11 ACSBG1 ACSBG1 ADIPOR1 ADIPOR1 TRAF2 TRAF2 LEP LEP STAT3 STAT3 LEPR LEPR AKT3 AKT3 NPY NPY G6PC2 G6PC2 ACSL5 ACSL5 ACSBG2 ACSBG2 PRKCQ PRKCQ IKBKB IKBKB MTOR MTOR ACSL4 ACSL4 NFKBIA NFKBIA IRS4 IRS4 SLC2A1 SLC2A1 PRKAG1 PRKAG1 MAPK10 MAPK10 PRKAA1 PRKAA1 TNFRSF1B TNFRSF1B PCK1 PCK1 PRKAA2 PRKAA2 ACACB ACACB RXRB RXRB ACSL1 ACSL1 PRKAB1 PRKAB1 CHUK CHUK CPT1A CPT1A RXRA RXRA AKT2 AKT2 AGRP AGRP CAMKK2 CAMKK2 NFKB1 NFKB1 POMC POMC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (720 aa)
PPARGC1APPARG coactivator 1 alpha. (798 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
ADIPOR2Adiponectin receptor 2. (386 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
RXRGRetinoid X receptor gamma. (463 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
ACSL6AMP-binding domain-containing protein. (722 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
MAPK9Mitogen-activated protein kinase. (387 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
CPT1CCarnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family. (803 aa)
JAK2Tyrosine-protein kinase. (1094 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (568 aa)
CPT1BCarnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
NFKBIENFKB inhibitor epsilon. (361 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
NFKBIBNFKB inhibitor beta. (356 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
ACSBG1Acyl-CoA synthetase bubblegum family member 1. (723 aa)
ADIPOR1Adiponectin receptor 1. (375 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (519 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
STAT3Signal transducer and activator of transcription. (802 aa)
LEPRLeptin receptor. (1163 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
NPYNeuropeptide Y. (97 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (354 aa)
ACSL5Acyl-CoA synthetase long chain family member 5. (725 aa)
ACSBG2Acyl-CoA synthetase bubblegum family member 2. (705 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (710 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (789 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (711 aa)
NFKBIAANK_REP_REGION domain-containing protein. (343 aa)
IRS4Insulin receptor substrate 4. (1227 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (506 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (331 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
PRKAA1Non-specific serine/threonine protein kinase. (697 aa)
TNFRSF1BTNF receptor superfamily member 1B. (462 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
PRKAA2Non-specific serine/threonine protein kinase. (560 aa)
ACACBAcetyl-CoA carboxylase beta. (2442 aa)
RXRBRetinoid X receptor beta. (542 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (721 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
RXRARetinoid X receptor alpha. (481 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
AGRPAgouti related neuropeptide. (132 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2. (588 aa)
NFKB1Nuclear factor kappa B subunit 1. (975 aa)
POMCProopiomelanocortin. (251 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
Server load: low (18%) [HD]