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ND1 ND1 ND2 ND2 COX1 COX1 COX2 COX2 ATP8 ATP8 ATP6 ATP6 COX3 COX3 ND3 ND3 ND4L ND4L ND4 ND4 ND5 ND5 ND6 ND6 CYTB CYTB ATP5F1C ATP5F1C LOC104679886 LOC104679886 CREBBP CREBBP ENSRROP00000000343 ENSRROP00000000343 ENSRROP00000000351 ENSRROP00000000351 NDUFA11 NDUFA11 TUBA1A TUBA1A LOC104669287 LOC104669287 COX7B2 COX7B2 LOC104669550 LOC104669550 ENSRROP00000001187 ENSRROP00000001187 NDUFB10 NDUFB10 LOC104681924 LOC104681924 DNAH11 DNAH11 KLC3 KLC3 LOC104661470 LOC104661470 LOC104658905 LOC104658905 NDUFS4 NDUFS4 PPARGC1A PPARGC1A LOC104672609 LOC104672609 ENSRROP00000002717 ENSRROP00000002717 MAP2K7 MAP2K7 ENSRROP00000002996 ENSRROP00000002996 ENSRROP00000003031 ENSRROP00000003031 GPX6 GPX6 COX6B2 COX6B2 UQCR10 UQCR10 KIF5B KIF5B NDUFA5 NDUFA5 PSMA8 PSMA8 ATP5F1E ATP5F1E PSMD8 PSMD8 KIF5C KIF5C ATP5MC2 ATP5MC2 ERN1 ERN1 MAPK8 MAPK8 ENSRROP00000004659 ENSRROP00000004659 NDUFS5 NDUFS5 POLR2F POLR2F CLTCL1 CLTCL1 ENSRROP00000005669 ENSRROP00000005669 POLR2D POLR2D COX6B1 COX6B1 LOC104670765 LOC104670765 WIPI1 WIPI1 TUBA8 TUBA8 ATG2A ATG2A NDUFC1 NDUFC1 ATG2B ATG2B VDAC1 VDAC1 LOC104668069 LOC104668069 PSMB6 PSMB6 BAX BAX LOC104661761 LOC104661761 LOC104661226 LOC104661226 GPX5 GPX5 MAPK9 MAPK9 POLR2B POLR2B SOD2 SOD2 REST REST NDUFC2 NDUFC2 DNAL1 DNAL1 STX1A STX1A NDUFA4L2 NDUFA4L2 ACTR10 ACTR10 ATP5PF ATP5PF PSMB2 PSMB2 SP1 SP1 POLR2A POLR2A TUBB1 TUBB1 GRIA3 GRIA3 COX7A2L COX7A2L NDUFV3 NDUFV3 LOC104666251 LOC104666251 PSMB4 PSMB4 NDUFB2 NDUFB2 PSMD7 PSMD7 SLC1A2 SLC1A2 TAF4B TAF4B AP2B1 AP2B1 NDUFB1 NDUFB1 DNALI1 DNALI1 COX6A2 COX6A2 NRF1 NRF1 CASP8 CASP8 DCTN1 DCTN1 GRIA1 GRIA1 ATG13 ATG13 ATP5MC1 ATP5MC1 DNAH10 DNAH10 MAP3K5 MAP3K5 KIF5A KIF5A NDUFS3 NDUFS3 NDUFA6 NDUFA6 PSMA2 PSMA2 UCP1 UCP1 GPX1 GPX1 NRBF2 NRBF2 ACTR1B ACTR1B PSMD11 PSMD11 TUBA3D TUBA3D NDUFS2 NDUFS2 NDUFA12 NDUFA12 DNAH6 DNAH6 PSMC6 PSMC6 CASP3 CASP3 PSMC2 PSMC2 CREB5 CREB5 HDAC2 HDAC2 DNAH3 DNAH3 TRAF2 TRAF2 LOC104665620 LOC104665620 DNAH12 DNAH12 POLR2G POLR2G ATG14 ATG14 DNAI2 DNAI2 PLCB3 PLCB3 RCOR1 RCOR1 DNAH9 DNAH9 NDUFS1 NDUFS1 ATG101 ATG101 PSMB5 PSMB5 NDUFB9 NDUFB9 ATP5PO ATP5PO NDUFA4 NDUFA4 DNAH5 DNAH5 PSMD14 PSMD14 AMBRA1 AMBRA1 NDUFA9 NDUFA9 KLC1 KLC1 NDUFB7 NDUFB7 APAF1 APAF1 DNAH17 DNAH17 SLC25A4 SLC25A4 PLCB1 PLCB1 CREB3 CREB3 CREB1 CREB1 TUBB TUBB PSMD3 PSMD3 POLR2J POLR2J SDHD SDHD DNAH14 DNAH14 NDUFS8 NDUFS8 KLC2 KLC2 COX8A COX8A ENSRROP00000023842 ENSRROP00000023842 DCTN5 DCTN5 UQCRQ UQCRQ DNAH2 DNAH2 DNAL4 DNAL4 PPIF PPIF PSMB1 PSMB1 VDAC2 VDAC2 ATP5F1B ATP5F1B MTOR MTOR PLCB4 PLCB4 COX5A COX5A ATP5PB ATP5PB PSMC4 PSMC4 TBP TBP TP53 TP53 DCTN4 DCTN4 RB1CC1 RB1CC1 SDHC SDHC CLTC CLTC SLC1A3 SLC1A3 BECN1 BECN1 NDUFV1 NDUFV1 LOC104661254 LOC104661254 PSMA1 PSMA1 EP300 EP300 UQCRC2 UQCRC2 LOC104662045 LOC104662045 LOC104679876 LOC104679876 DNAI1 DNAI1 COX8C COX8C COX4I2 COX4I2 MAPK10 MAPK10 SLC25A6 SLC25A6 DCTN2 DCTN2 LOC104677352 LOC104677352 DNAH8 DNAH8 IFT57 IFT57 PIK3R4 PIK3R4 BDNF BDNF GPX3 GPX3 DNAH7-2 DNAH7-2 DCTN6 DCTN6 LOC104670398 LOC104670398 ACTR1A ACTR1A UQCRB UQCRB MAP3K10 MAP3K10 LOC104656020 LOC104656020 PIK3C3 PIK3C3 PSMA5 PSMA5 HTT HTT AP2A1 AP2A1 TBPL2 TBPL2 TBPL1 TBPL1 PSMA4 PSMA4 POLR2H POLR2H GPX8 GPX8 NDUFA1 NDUFA1 TUBB6 TUBB6 PSMB3 PSMB3 GRIA2 GRIA2 PSMA3 PSMA3 NDUFV2 NDUFV2 NDUFB3 NDUFB3 LOC104662117 LOC104662117 NDUFA8 NDUFA8 GNAQ GNAQ GRM5 GRM5 TUBAL3 TUBAL3 CASP9 CASP9 ATP5MC3 ATP5MC3 CREB3L1 CREB3L1 SDHB SDHB TUBA1C TUBA1C NDUFA7 NDUFA7 PSMC3 PSMC3 NDUFB6 NDUFB6 KCNJ10 KCNJ10 PSMD9 PSMD9 DNAH1 DNAH1 SEM1-2 SEM1-2 PSMD6 PSMD6 GPX2 GPX2 NDUFB5 NDUFB5 POLR2I POLR2I PSMA7 PSMA7 HIP1 HIP1 PSMA6 PSMA6 DCTN3 DCTN3 TAF4 TAF4 PSMB7 PSMB7 AP2A2 AP2A2 NDUFB8 NDUFB8 TUBB3 TUBB3 NDUFA13 NDUFA13 CYC1 CYC1 PSMC5 PSMC5 POLR2E POLR2E CACNA1B CACNA1B POLR2K POLR2K NDUFB11 NDUFB11 VDAC3 VDAC3 PSMD13 PSMD13 NDUFA2 NDUFA2 PSMD4 PSMD4 ATP5F1D ATP5F1D SOD1 SOD1 GRIA4 GRIA4 UQCRC1 UQCRC1 PSMD2 PSMD2 SIN3A SIN3A PPARG PPARG ITPR1 ITPR1 TUBA4A TUBA4A PSMD1 PSMD1 GPX7 GPX7 CREB3L2 CREB3L2 GRIN2B GRIN2B AP2S1 AP2S1 NDUFB4 NDUFB4 LOC104656160 LOC104656160 ATP5F1A ATP5F1A POLR2C POLR2C KLC4 KLC4
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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gene neighborhood
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ND1NADH-ubiquinone oxidoreductase chain 1; Belongs to the complex I subunit 1 family. (318 aa)
ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (347 aa)
COX1Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (514 aa)
COX2Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (227 aa)
ATP8ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (64 aa)
ATP6ATP synthase subunit a. (226 aa)
COX3Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (261 aa)
ND3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (115 aa)
ND4LNADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (98 aa)
ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (459 aa)
ND5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (603 aa)
ND6NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (174 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (378 aa)
ATP5F1CATP synthase subunit gamma. (293 aa)
LOC104679886Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
CREBBPCREB binding protein. (2442 aa)
ENSRROP00000000343Uncharacterized protein. (63 aa)
ENSRROP00000000351Uncharacterized protein. (67 aa)
NDUFA11NADH:ubiquinone oxidoreductase subunit A11. (202 aa)
TUBA1ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
LOC104669287Uncharacterized protein. (115 aa)
COX7B2Cytochrome c oxidase subunit 7B2. (81 aa)
LOC104669550Uncharacterized protein. (80 aa)
ENSRROP00000001187Uncharacterized protein. (63 aa)
NDUFB10NADH:ubiquinone oxidoreductase subunit B10. (178 aa)
LOC104681924Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
DNAH11Dynein axonemal heavy chain 11. (3390 aa)
KLC3Kinesin light chain 3. (504 aa)
LOC104661470Uncharacterized protein. (129 aa)
LOC104658905AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (174 aa)
PPARGC1APPARG coactivator 1 alpha. (798 aa)
LOC104672609Uncharacterized protein. (63 aa)
ENSRROP00000002717Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (403 aa)
ENSRROP00000002996Uncharacterized protein. (63 aa)
ENSRROP00000003031Uncharacterized protein. (82 aa)
GPX6Glutathione peroxidase 6. (219 aa)
COX6B2Cytochrome c oxidase subunit 6B2. (63 aa)
UQCR10Ubiquinol-cytochrome c reductase, complex III subunit X. (63 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (964 aa)
NDUFA5NADH:ubiquinone oxidoreductase subunit A5. (116 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
ATP5F1EATP synthase F1 subunit epsilon. (51 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
KIF5CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (930 aa)
ATP5MC2ATP synthase membrane subunit c locus 2; Belongs to the ATPase C chain family. (198 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (980 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
ENSRROP00000004659Uncharacterized protein. (63 aa)
NDUFS5NADH:ubiquinone oxidoreductase subunit S5. (106 aa)
POLR2FRNA polymerase II subunit F. (150 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1680 aa)
ENSRROP00000005669Uncharacterized protein. (63 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
COX6B1Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (87 aa)
LOC104670765Uncharacterized protein. (248 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (446 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
ATG2AAutophagy related 2A. (1936 aa)
NDUFC1NADH:ubiquinone oxidoreductase subunit C1. (76 aa)
ATG2BAutophagy related 2B. (2078 aa)
VDAC1Voltage dependent anion channel 1. (283 aa)
LOC104668069Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa)
PSMB6Proteasome subunit beta. (242 aa)
BAXBCL2 associated X, apoptosis regulator. (197 aa)
LOC104661761Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (102 aa)
LOC104661226Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (441 aa)
GPX5Glutathione peroxidase; Belongs to the glutathione peroxidase family. (221 aa)
MAPK9Mitogen-activated protein kinase. (387 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
SOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
RESTRE1 silencing transcription factor. (1096 aa)
NDUFC2NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (119 aa)
DNAL1Dynein axonemal light chain 1. (190 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (289 aa)
NDUFA4L2NDUFA4 mitochondrial complex associated like 2. (94 aa)
ACTR10Actin related protein 10; Belongs to the actin family. (417 aa)
ATP5PFATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (119 aa)
PSMB2Proteasome subunit beta. (201 aa)
SP1Sp1 transcription factor. (786 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1992 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (534 aa)
COX7A2LCytochrome c oxidase subunit 7A2 like. (114 aa)
NDUFV3NADH:ubiquinone oxidoreductase subunit V3. (473 aa)
LOC104666251Cytochrome c oxidase subunit 6A, mitochondrial. (109 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
NDUFB2NADH:ubiquinone oxidoreductase subunit B2. (105 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
SLC1A2Amino acid transporter. (574 aa)
TAF4BTATA-box binding protein associated factor 4b. (862 aa)
AP2B1AP complex subunit beta. (959 aa)
NDUFB1Uncharacterized protein. (106 aa)
DNALI1Dynein axonemal light intermediate chain 1. (258 aa)
COX6A2Cytochrome c oxidase subunit 6A, mitochondrial. (97 aa)
NRF1Nuclear respiratory factor 1. (522 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (542 aa)
DCTN1CAP-Gly domain-containing protein. (1278 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (617 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa)
ATP5MC1ATP synthase membrane subunit c locus 1; Belongs to the ATPase C chain family. (135 aa)
DNAH10Dynein axonemal heavy chain 10. (4533 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1374 aa)
KIF5AKinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1033 aa)
NDUFS3NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (266 aa)
NDUFA6NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (128 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
UCP1Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (200 aa)
NRBF2Nuclear receptor binding factor 2. (289 aa)
ACTR1BActin related protein 1B. (376 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
TUBA3DTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (459 aa)
NDUFS2NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (463 aa)
NDUFA12NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (145 aa)
DNAH6Dynein axonemal heavy chain 6. (3510 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
CASP3Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa)
PSMC2AAA domain-containing protein; Belongs to the AAA ATPase family. (467 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
DNAH3Dynein axonemal heavy chain 3. (4089 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (519 aa)
LOC104665620Uncharacterized protein. (248 aa)
DNAH12Uncharacterized protein. (3959 aa)
POLR2GRNA polymerase II subunit G. (255 aa)
ATG14Autophagy related 14. (492 aa)
DNAI2Dynein axonemal intermediate chain 2. (605 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
RCOR1REST corepressor 1. (486 aa)
DNAH9Dynein axonemal heavy chain 9. (4437 aa)
NDUFS1NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (741 aa)
ATG101Autophagy related 101. (218 aa)
PSMB5Proteasome subunit beta. (271 aa)
NDUFB9NADH:ubiquinone oxidoreductase subunit B9; Belongs to the complex I LYR family. (202 aa)
ATP5POUncharacterized protein. (213 aa)
NDUFA4NDUFA4 mitochondrial complex associated. (81 aa)
DNAH5Dynein axonemal heavy chain 5. (4556 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (315 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1298 aa)
NDUFA9NADH:ubiquinone oxidoreductase subunit A9. (377 aa)
KLC1Uncharacterized protein. (639 aa)
NDUFB7NADH:ubiquinone oxidoreductase subunit B7. (137 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa)
DNAH17Dynein axonemal heavy chain 17. (4462 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1114 aa)
CREB3cAMP responsive element binding protein 3. (372 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
TUBBTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
POLR2JRNA_pol_L_2 domain-containing protein. (158 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa)
DNAH14Dynein axonemal heavy chain 14. (430 aa)
NDUFS8NADH:ubiquinone oxidoreductase core subunit S8. (210 aa)
KLC2Kinesin light chain 2. (652 aa)
COX8ACytochrome c oxidase subunit 8A. (69 aa)
ENSRROP00000023842Uncharacterized protein; Belongs to the tubulin family. (372 aa)
DCTN5Dynactin subunit 5. (182 aa)
UQCRQUbiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
DNAH2Dynein axonemal heavy chain 2. (4427 aa)
DNAL4Dynein light chain. (105 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (206 aa)
PSMB1Proteasome subunit beta. (241 aa)
VDAC2Voltage dependent anion channel 2. (308 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (535 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1225 aa)
COX5ACytochrome c oxidase subunit 5A. (149 aa)
ATP5PBUncharacterized protein. (255 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (421 aa)
TBPTATA-box binding protein. (333 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
DCTN4Dynactin subunit 4. (467 aa)
RB1CC1RB1 inducible coiled-coil 1. (1576 aa)
SDHCUncharacterized protein. (169 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1682 aa)
SLC1A3Amino acid transporter. (542 aa)
BECN1Beclin 1. (450 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa)
LOC104661254Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
EP300E1A binding protein p300. (2413 aa)
UQCRC2Ubiquinol-cytochrome c reductase core protein 2; Belongs to the peptidase M16 family. (453 aa)
LOC104662045Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (568 aa)
LOC104679876COX6C domain-containing protein. (75 aa)
DNAI1Dynein axonemal intermediate chain 1. (704 aa)
COX8CCytochrome c oxidase subunit 8C. (72 aa)
COX4I2Cytochrome c oxidase subunit 4I2. (172 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
SLC25A6Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
DCTN2Dynactin subunit 2. (427 aa)
LOC104677352Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (484 aa)
DNAH8Dynein axonemal heavy chain 8. (4708 aa)
IFT57Intraflagellar transport 57. (428 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (312 aa)
GPX3Glutathione peroxidase; Belongs to the glutathione peroxidase family. (225 aa)
DNAH7-2Uncharacterized protein. (677 aa)
DCTN6Dynactin subunit 6. (190 aa)
LOC104670398Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (467 aa)
ACTR1AActin related protein 1A. (377 aa)
UQCRBUbiquinol-cytochrome c reductase binding protein. (159 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase. (952 aa)
LOC104656020Uncharacterized protein. (169 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (911 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
HTTHuntingtin. (3100 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (1036 aa)
TBPL2TATA-box binding protein like 2. (376 aa)
TBPL1TATA-box binding protein like 1. (186 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
POLR2HRNA polymerase II subunit H. (174 aa)
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
NDUFA1NADH:ubiquinone oxidoreductase subunit A1. (74 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (374 aa)
PSMB3Proteasome subunit beta. (205 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
PSMA3Proteasome subunit alpha type. (277 aa)
NDUFV2NADH:ubiquinone oxidoreductase core subunit V2. (249 aa)
NDUFB3NADH:ubiquinone oxidoreductase subunit B3. (98 aa)
LOC104662117Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (91 aa)
NDUFA8NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (172 aa)
GNAQG protein subunit alpha q. (359 aa)
GRM5Glutamate metabotropic receptor 5. (1212 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (421 aa)
ATP5MC3ATP synthase membrane subunit c locus 3; Belongs to the ATPase C chain family. (141 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa)
TUBA1CTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (489 aa)
NDUFA7Uncharacterized protein. (113 aa)
PSMC3AAA domain-containing protein; Belongs to the AAA ATPase family. (447 aa)
NDUFB6NADH:ubiquinone oxidoreductase subunit B6. (128 aa)
KCNJ10IRK domain-containing protein. (207 aa)
PSMD9PDZ domain-containing protein. (223 aa)
DNAH1Dynein axonemal heavy chain 1. (4265 aa)
SEM1-2Uncharacterized protein. (89 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
GPX2Glutathione peroxidase; Belongs to the glutathione peroxidase family. (150 aa)
NDUFB5Uncharacterized protein. (189 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
PSMA7Proteasome endopeptidase complex. (248 aa)
HIP1Huntingtin interacting protein 1. (1037 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
DCTN3Dynactin subunit 3. (186 aa)
TAF4TATA-box binding protein associated factor 4. (635 aa)
PSMB7Proteasome subunit beta. (302 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (943 aa)
NDUFB8NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa)
TUBB3G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the tubulin family. (791 aa)
NDUFA13NADH:ubiquinone oxidoreductase subunit A13. (151 aa)
CYC1Cytochrome c1. (325 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (444 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2301 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
NDUFB11NADH:ubiquinone oxidoreductase subunit B11. (154 aa)
VDAC3Uncharacterized protein. (284 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (399 aa)
NDUFA2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (99 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (378 aa)
ATP5F1DATP synthase F1 subunit delta. (168 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (819 aa)
UQCRC1Ubiquinol-cytochrome c reductase core protein 1. (480 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2714 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (193 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
NDUFB4Uncharacterized protein. (129 aa)
LOC104656160Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (641 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
KLC4Kinesin light chain 4. (619 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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