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ND1 ND1 ND2 ND2 COX1 COX1 COX2 COX2 ATP8 ATP8 ATP6 ATP6 COX3 COX3 ND3 ND3 ND4L ND4L ND4 ND4 ND5 ND5 ND6 ND6 CYTB CYTB GSK3B GSK3B ATP5F1C ATP5F1C LOC104679886 LOC104679886 ENSRROP00000000343 ENSRROP00000000343 NDUFA11 NDUFA11 TUBA1A TUBA1A HSPA1L HSPA1L LOC104669287 LOC104669287 COX7B2 COX7B2 LOC104669550 LOC104669550 ENSRROP00000001187 ENSRROP00000001187 NDUFB10 NDUFB10 IL6 IL6 LOC104681924 LOC104681924 KLC3 KLC3 LOC104661470 LOC104661470 LOC104658905 LOC104658905 NDUFS4 NDUFS4 LOC104672609 LOC104672609 ENSRROP00000002717 ENSRROP00000002717 ATF6B ATF6B ENSRROP00000002996 ENSRROP00000002996 ENSRROP00000003031 ENSRROP00000003031 COX6B2 COX6B2 UQCR10 UQCR10 KIF5B KIF5B NDUFA5 NDUFA5 PSMA8 PSMA8 ATP5F1E ATP5F1E PSMD8 PSMD8 KIF5C KIF5C CAV3 CAV3 ATP5MC2 ATP5MC2 IL1A IL1A MAPK8 MAPK8 ENSRROP00000004659 ENSRROP00000004659 NDUFS5 NDUFS5 TNF TNF PRKACB PRKACB ENSRROP00000005669 ENSRROP00000005669 COX6B1 COX6B1 TUBA8 TUBA8 NDUFC1 NDUFC1 DDIT3 DDIT3 VDAC1 VDAC1 LOC104668069 LOC104668069 LAMC1 LAMC1 PSMB6 PSMB6 BAX BAX LOC104661761 LOC104661761 LOC104661226 LOC104661226 ATF4 ATF4 MAPK9 MAPK9 HSPA8-2 HSPA8-2 GRIN3B GRIN3B NDUFC2 NDUFC2 HSPA6 HSPA6 HSPA5 HSPA5 C6 C6 NDUFA4L2 NDUFA4L2 ATP5PF ATP5PF PSMB2 PSMB2 C1QC C1QC ATF2 ATF2 TUBB1 TUBB1 COX7A2L COX7A2L NDUFV3 NDUFV3 LOC104666251 LOC104666251 PSMB4 PSMB4 NDUFB2 NDUFB2 PSMD7 PSMD7 PRKACA PRKACA EIF2S1 EIF2S1 NDUFB1 NDUFB1 PIK3CA PIK3CA PRKCD PRKCD COX6A2 COX6A2 PIK3CD PIK3CD C8A C8A GRIN3A GRIN3A LOC104654621 LOC104654621 ATP5MC1 ATP5MC1 STIP1 STIP1 PPP3R1 PPP3R1 KIF5A KIF5A NDUFS3 NDUFS3 NDUFA6 NDUFA6 PSMA2 PSMA2 CYBB CYBB PSMD11 PSMD11 TUBA3D TUBA3D PPP3CB PPP3CB NDUFS2 NDUFS2 NDUFA12 NDUFA12 PSMC6 PSMC6 CASP3 CASP3 PSMC2 PSMC2 CREB5 CREB5 FYN FYN NDUFS1 NDUFS1 BAD BAD PSMB5 PSMB5 NDUFB9 NDUFB9 ATP5PO ATP5PO NDUFA4 NDUFA4 PSMD14 PSMD14 PIK3R1 PIK3R1 NDUFA9 NDUFA9 C1QA C1QA CAV2 CAV2 KLC1 KLC1 NDUFB7 NDUFB7 APAF1 APAF1 C9 C9 SLC25A4 SLC25A4 CREB3 CREB3 CREB1 CREB1 TUBB TUBB ITPR2 ITPR2 CACNA1D CACNA1D PSMD3 PSMD3 SDHD SDHD NDUFS8 NDUFS8 KLC2 KLC2 COX8A COX8A ENSRROP00000023842 ENSRROP00000023842 UQCRQ UQCRQ CAV1 CAV1 PPIF PPIF MAPK1 MAPK1 PSMB1 PSMB1 VDAC2 VDAC2 CACNA1S CACNA1S ATP5F1B ATP5F1B MAPK14 MAPK14 COX5A COX5A NCF1 NCF1 ATP5PB ATP5PB PPP3CC PPP3CC PSMC4 PSMC4 SDHC SDHC C5 C5 NDUFV1 NDUFV1 LOC104661254 LOC104661254 PSMA1 PSMA1 UQCRC2 UQCRC2 LOC104662045 LOC104662045 LOC104679876 LOC104679876 COX8C COX8C COX4I2 COX4I2 MAPK10 MAPK10 PRNP PRNP SLC25A6 SLC25A6 CACNA1C CACNA1C RYR1 RYR1 RYR3 RYR3 C1QB C1QB EIF2AK3 EIF2AK3 LOC104670398 LOC104670398 PIK3R3 PIK3R3 UQCRB UQCRB LOC104656020 LOC104656020 MAPK3 MAPK3 PSMA5 PSMA5 NCF4 NCF4 PSMA4 PSMA4 NDUFA1 NDUFA1 TUBB6 TUBB6 PSMB3 PSMB3 C7 C7 PSMA3 PSMA3 NDUFV2 NDUFV2 NDUFB3 NDUFB3 IL1B IL1B CACNA1F CACNA1F LOC104662117 LOC104662117 NDUFA8 NDUFA8 ITPR3 ITPR3 RYR2 RYR2 CYBA CYBA TUBAL3 TUBAL3 CASP9 CASP9 ATP5MC3 ATP5MC3 CREB3L1 CREB3L1 SDHB SDHB TUBA1C TUBA1C NDUFA7 NDUFA7 PSMC3 PSMC3 NDUFB6 NDUFB6 PSMD9 PSMD9 SEM1-2 SEM1-2 PSMD6 PSMD6 CSNK2A1 CSNK2A1 NDUFB5 NDUFB5 C8G C8G RAC2 RAC2 PSMA7 PSMA7 PSMA6 PSMA6 PSMB7 PSMB7 NDUFB8 NDUFB8 TUBB3 TUBB3 NDUFA13 NDUFA13 CYC1 CYC1 PSMC5 PSMC5 NOTCH1 NOTCH1 CACNA1B CACNA1B NDUFB11 NDUFB11 VDAC3 VDAC3 PSMD13 PSMD13 NCF2 NCF2 NDUFA2 NDUFA2 PSMD4 PSMD4 ATP5F1D ATP5F1D SOD1 SOD1 CSNK2B CSNK2B EGR1 EGR1 UQCRC1 UQCRC1 MCU MCU PSMD2 PSMD2 GRIN2A GRIN2A PIK3CB PIK3CB ITPR1 ITPR1 TUBA4A TUBA4A PSMD1 PSMD1 CREB3L2 CREB3L2 GRIN2B GRIN2B NDUFB4 NDUFB4 LOC104656160 LOC104656160 PPP3CA PPP3CA ATP5F1A ATP5F1A KLC4 KLC4
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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ND1NADH-ubiquinone oxidoreductase chain 1; Belongs to the complex I subunit 1 family. (318 aa)
ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (347 aa)
COX1Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (514 aa)
COX2Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (227 aa)
ATP8ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (64 aa)
ATP6ATP synthase subunit a. (226 aa)
COX3Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (261 aa)
ND3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (115 aa)
ND4LNADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (98 aa)
ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (459 aa)
ND5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (603 aa)
ND6NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (174 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (378 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (309 aa)
ATP5F1CATP synthase subunit gamma. (293 aa)
LOC104679886Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSRROP00000000343Uncharacterized protein. (63 aa)
NDUFA11NADH:ubiquinone oxidoreductase subunit A11. (202 aa)
TUBA1ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
HSPA1LHeat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (641 aa)
LOC104669287Uncharacterized protein. (115 aa)
COX7B2Cytochrome c oxidase subunit 7B2. (81 aa)
LOC104669550Uncharacterized protein. (80 aa)
ENSRROP00000001187Uncharacterized protein. (63 aa)
NDUFB10NADH:ubiquinone oxidoreductase subunit B10. (178 aa)
IL6Interleukin 6. (214 aa)
LOC104681924Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
KLC3Kinesin light chain 3. (504 aa)
LOC104661470Uncharacterized protein. (129 aa)
LOC104658905AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (174 aa)
LOC104672609Uncharacterized protein. (63 aa)
ENSRROP00000002717Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
ATF6BActivating transcription factor 6 beta. (708 aa)
ENSRROP00000002996Uncharacterized protein. (63 aa)
ENSRROP00000003031Uncharacterized protein. (82 aa)
COX6B2Cytochrome c oxidase subunit 6B2. (63 aa)
UQCR10Ubiquinol-cytochrome c reductase, complex III subunit X. (63 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (964 aa)
NDUFA5NADH:ubiquinone oxidoreductase subunit A5. (116 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
ATP5F1EATP synthase F1 subunit epsilon. (51 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
KIF5CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (930 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
ATP5MC2ATP synthase membrane subunit c locus 2; Belongs to the ATPase C chain family. (198 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (271 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
ENSRROP00000004659Uncharacterized protein. (63 aa)
NDUFS5NADH:ubiquinone oxidoreductase subunit S5. (106 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ENSRROP00000005669Uncharacterized protein. (63 aa)
COX6B1Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (87 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
NDUFC1NADH:ubiquinone oxidoreductase subunit C1. (76 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
VDAC1Voltage dependent anion channel 1. (283 aa)
LOC104668069Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa)
LAMC1Laminin subunit gamma 1. (1608 aa)
PSMB6Proteasome subunit beta. (242 aa)
BAXBCL2 associated X, apoptosis regulator. (197 aa)
LOC104661761Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (102 aa)
LOC104661226Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (441 aa)
ATF4Activating transcription factor 4. (351 aa)
MAPK9Mitogen-activated protein kinase. (387 aa)
HSPA8-2Uncharacterized protein. (129 aa)
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1037 aa)
NDUFC2NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (119 aa)
HSPA6Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family. (608 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
C6Complement C6. (934 aa)
NDUFA4L2NDUFA4 mitochondrial complex associated like 2. (94 aa)
ATP5PFATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (119 aa)
PSMB2Proteasome subunit beta. (201 aa)
C1QCComplement C1q C chain. (239 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
COX7A2LCytochrome c oxidase subunit 7A2 like. (114 aa)
NDUFV3NADH:ubiquinone oxidoreductase subunit V3. (473 aa)
LOC104666251Cytochrome c oxidase subunit 6A, mitochondrial. (109 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
NDUFB2NADH:ubiquinone oxidoreductase subunit B2. (105 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (295 aa)
NDUFB1Uncharacterized protein. (106 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
COX6A2Cytochrome c oxidase subunit 6A, mitochondrial. (97 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
C8AComplement C8 alpha chain. (584 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1115 aa)
LOC104654621Uncharacterized protein. (361 aa)
ATP5MC1ATP synthase membrane subunit c locus 1; Belongs to the ATPase C chain family. (135 aa)
STIP1Stress induced phosphoprotein 1. (591 aa)
PPP3R1Uncharacterized protein. (189 aa)
KIF5AKinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1033 aa)
NDUFS3NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (266 aa)
NDUFA6NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (128 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
CYBBCytochrome b-245 beta chain. (570 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
TUBA3DTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (459 aa)
PPP3CBSerine/threonine-protein phosphatase. (521 aa)
NDUFS2NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (463 aa)
NDUFA12NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (145 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
CASP3Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa)
PSMC2AAA domain-containing protein; Belongs to the AAA ATPase family. (467 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
FYNTyrosine-protein kinase. (537 aa)
NDUFS1NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (741 aa)
BADBCL2 associated agonist of cell death. (167 aa)
PSMB5Proteasome subunit beta. (271 aa)
NDUFB9NADH:ubiquinone oxidoreductase subunit B9; Belongs to the complex I LYR family. (202 aa)
ATP5POUncharacterized protein. (213 aa)
NDUFA4NDUFA4 mitochondrial complex associated. (81 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (315 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
NDUFA9NADH:ubiquinone oxidoreductase subunit A9. (377 aa)
C1QAComplement C1q A chain. (245 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
KLC1Uncharacterized protein. (639 aa)
NDUFB7NADH:ubiquinone oxidoreductase subunit B7. (137 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa)
C9Complement C9. (561 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
CREB3cAMP responsive element binding protein 3. (372 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
TUBBTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa)
NDUFS8NADH:ubiquinone oxidoreductase core subunit S8. (210 aa)
KLC2Kinesin light chain 2. (652 aa)
COX8ACytochrome c oxidase subunit 8A. (69 aa)
ENSRROP00000023842Uncharacterized protein; Belongs to the tubulin family. (372 aa)
UQCRQUbiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (206 aa)
MAPK1Mitogen-activated protein kinase. (330 aa)
PSMB1Proteasome subunit beta. (241 aa)
VDAC2Voltage dependent anion channel 2. (308 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (535 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
COX5ACytochrome c oxidase subunit 5A. (149 aa)
NCF1Neutrophil cytosolic factor 1. (390 aa)
ATP5PBUncharacterized protein. (255 aa)
PPP3CCSerine/threonine-protein phosphatase. (520 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (421 aa)
SDHCUncharacterized protein. (169 aa)
C5Complement C5. (950 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa)
LOC104661254Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
UQCRC2Ubiquinol-cytochrome c reductase core protein 2; Belongs to the peptidase M16 family. (453 aa)
LOC104662045Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (568 aa)
LOC104679876COX6C domain-containing protein. (75 aa)
COX8CCytochrome c oxidase subunit 8C. (72 aa)
COX4I2Cytochrome c oxidase subunit 4I2. (172 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
PRNPMajor prion protein; Belongs to the prion family. (230 aa)
SLC25A6Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
CACNA1CCa_chan_IQ domain-containing protein. (829 aa)
RYR1Ryanodine receptor 1. (4931 aa)
RYR3Ryanodine receptor 3. (4851 aa)
C1QBComplement C1q B chain. (253 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1115 aa)
LOC104670398Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (467 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
UQCRBUbiquinol-cytochrome c reductase binding protein. (159 aa)
LOC104656020Uncharacterized protein. (169 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
NCF4Neutrophil cytosolic factor 4. (339 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
NDUFA1NADH:ubiquinone oxidoreductase subunit A1. (74 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (374 aa)
PSMB3Proteasome subunit beta. (205 aa)
C7Complement C7. (843 aa)
PSMA3Proteasome subunit alpha type. (277 aa)
NDUFV2NADH:ubiquinone oxidoreductase core subunit V2. (249 aa)
NDUFB3NADH:ubiquinone oxidoreductase subunit B3. (98 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1971 aa)
LOC104662117Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (91 aa)
NDUFA8NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (172 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2703 aa)
RYR2Ryanodine receptor 2. (4938 aa)
CYBACytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (194 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (421 aa)
ATP5MC3ATP synthase membrane subunit c locus 3; Belongs to the ATPase C chain family. (141 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa)
TUBA1CTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (489 aa)
NDUFA7Uncharacterized protein. (113 aa)
PSMC3AAA domain-containing protein; Belongs to the AAA ATPase family. (447 aa)
NDUFB6NADH:ubiquinone oxidoreductase subunit B6. (128 aa)
PSMD9PDZ domain-containing protein. (223 aa)
SEM1-2Uncharacterized protein. (89 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (389 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
NDUFB5Uncharacterized protein. (189 aa)
C8GComplement C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family. (202 aa)
RAC2Rac family small GTPase 2. (192 aa)
PSMA7Proteasome endopeptidase complex. (248 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMB7Proteasome subunit beta. (302 aa)
NDUFB8NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa)
TUBB3G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the tubulin family. (791 aa)
NDUFA13NADH:ubiquinone oxidoreductase subunit A13. (151 aa)
CYC1Cytochrome c1. (325 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (444 aa)
NOTCH1Notch receptor 1. (2560 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2301 aa)
NDUFB11NADH:ubiquinone oxidoreductase subunit B11. (154 aa)
VDAC3Uncharacterized protein. (284 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (399 aa)
NCF2Neutrophil cytosolic factor 2. (526 aa)
NDUFA2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (99 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (378 aa)
ATP5F1DATP synthase F1 subunit delta. (168 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
CSNK2BUncharacterized protein. (298 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (541 aa)
UQCRC1Ubiquinol-cytochrome c reductase core protein 1. (480 aa)
MCUMitochondrial calcium uniporter. (351 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2714 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
NDUFB4Uncharacterized protein. (129 aa)
LOC104656160Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa)
PPP3CASerine/threonine-protein phosphatase. (417 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (641 aa)
KLC4Kinesin light chain 4. (619 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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