STRINGSTRING
LOC104664197 LOC104664197 CASP7 CASP7 LOC104662256 LOC104662256 IL6 IL6 CXCL5 CXCL5 NOD1 NOD1 NOS2 NOS2 TICAM2 TICAM2 RELA RELA IL1A IL1A MAPK8 MAPK8 CALML3 CALML3 TNF TNF MAPK9 MAPK9 ITGAM ITGAM MYD88 MYD88 C1QC C1QC GNAI2 GNAI2 IL12B IL12B RHOA RHOA CASP3 CASP3 TLR4 TLR4 GNAI3 GNAI3 C4BPB C4BPB LOC104654808 LOC104654808 CALM3 CALM3 IRF3 IRF3 GNAI1 GNAI1 LOC104662255 LOC104662255 ENSRROP00000019822 ENSRROP00000019822 C1QA C1QA CXCL6 CXCL6 MAPK1 MAPK1 LY96 LY96 MAPK14 MAPK14 IRAK4 IRAK4 CFL2 CFL2 C4BPA C4BPA C5 C5 MAPK10 MAPK10 CD14 CD14 LOC104681686 LOC104681686 FOS FOS CFL1 CFL1 C1QB C1QB SERPING1 SERPING1 LOC104665273 LOC104665273 MAPK3 MAPK3 LOC104662055 LOC104662055 IRF8 IRF8 IL1B IL1B IRF1 IRF1 CASP1 CASP1 C4A C4A TRAF6 TRAF6 IL12A IL12A IRAK1 IRAK1 PYCARD PYCARD LOC104681692 LOC104681692 CALML6 CALML6 C3 C3 ITGB2 ITGB2 IL10 IL10 ITGB1 ITGB1 TIRAP TIRAP CXCL8 CXCL8 CALML4 CALML4 NFKB1 NFKB1 IL23A IL23A ITGA5 ITGA5 NLRP3 NLRP3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC104664197Uncharacterized protein. (603 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (336 aa)
LOC104662256C-type lectin domain-containing protein. (248 aa)
IL6Interleukin 6. (214 aa)
CXCL5C-X-C motif chemokine. (114 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1153 aa)
TICAM2Toll like receptor adaptor molecule 2. (234 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (271 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
MAPK9Mitogen-activated protein kinase. (387 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1198 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
C1QCComplement C1q C chain. (239 aa)
GNAI2G protein subunit alpha i2. (355 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa)
RHOARas homolog family member A. (193 aa)
CASP3Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
GNAI3G protein subunit alpha i3. (354 aa)
C4BPBComplement component 4 binding protein beta. (252 aa)
LOC104654808C-X-C motif chemokine. (111 aa)
CALM3Calmodulin 1; Belongs to the calmodulin family. (149 aa)
IRF3IRF tryptophan pentad repeat domain-containing protein. (426 aa)
GNAI1G protein subunit alpha i1. (253 aa)
LOC104662255C-type lectin domain-containing protein. (271 aa)
ENSRROP00000019822Uncharacterized protein; Belongs to the calmodulin family. (141 aa)
C1QAComplement C1q A chain. (245 aa)
CXCL6C-X-C motif chemokine. (123 aa)
MAPK1Mitogen-activated protein kinase. (330 aa)
LY96Lymphocyte antigen 96. (160 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (460 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
C4BPAComplement component 4 binding protein alpha. (582 aa)
C5Complement C5. (950 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
CD14CD14 molecule. (384 aa)
LOC104681686Uncharacterized protein; Belongs to the peptidase S1 family. (739 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (212 aa)
C1QBComplement C1q B chain. (253 aa)
SERPING1Serpin family G member 1; Belongs to the serpin family. (534 aa)
LOC104665273Uncharacterized protein; Belongs to the peptidase C14A family. (406 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
LOC104662055EF-hand domain-containing protein; Belongs to the calmodulin family. (75 aa)
IRF8Interferon regulatory factor 8. (433 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
IRF1Interferon regulatory factor. (325 aa)
CASP1Caspase 1; Belongs to the peptidase C14A family. (404 aa)
C4AUncharacterized protein. (1625 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (707 aa)
PYCARDPYD and CARD domain containing. (195 aa)
LOC104681692Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (289 aa)
CALML6Calmodulin like 6. (181 aa)
C3Complement C3. (1663 aa)
ITGB2Integrin beta. (769 aa)
IL10Interleukin 10. (178 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
TIRAPTIR domain containing adaptor protein. (219 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
CALML4Calmodulin like 4. (192 aa)
NFKB1Nuclear factor kappa B subunit 1. (975 aa)
IL23AInterleukin 23 subunit alpha. (189 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1098 aa)
NLRP3NLR family pyrin domain containing 3. (1035 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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