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| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (309 aa) |
| | LOC104679886 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | CCR5 | C-C motif chemokine receptor 5 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family. (352 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1043 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | IFNB1 | Interferon beta 1. (187 aa) |
| | IL6 | Interleukin 6. (214 aa) |
| | LOC104681924 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | ITGAV | Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa) |
| | ENSRROP00000002717 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) |
| | ATF6B | Activating transcription factor 6 beta. (708 aa) |
| | ADCY5 | Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (864 aa) |
| | E2F3 | E2F transcription factor 3. (465 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | PTGER2 | Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (358 aa) |
| | ARHGEF12 | Rho guanine nucleotide exchange factor 12. (1544 aa) |
| | TAP1 | Transporter 1, ATP binding cassette subfamily B member. (808 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (914 aa) |
| | CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) |
| | GNB3 | G protein subunit beta 3. (340 aa) |
| | GNA13 | G protein subunit alpha 13. (308 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (197 aa) |
| | LOC104661761 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (102 aa) |
| | ATF4 | Activating transcription factor 4. (351 aa) |
| | ARHGEF11 | Rho guanine nucleotide exchange factor 11. (1561 aa) |
| | NFATC1 | Nuclear factor of activated T cells 1. (895 aa) |
| | GNG7 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) |
| | ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa) |
| | GNAI2 | G protein subunit alpha i2. (355 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | CXCR4 | C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (415 aa) |
| | SP1 | Sp1 transcription factor. (786 aa) |
| | E2F2 | E2F transcription factor 2. (437 aa) |
| | B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | GNG13 | G protein subunit gamma 13. (67 aa) |
| | IL1R1 | Interleukin 1 receptor type 1. (569 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | IL10RB | Interleukin 10 receptor subunit beta. (325 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | ADCY2 | Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa) |
| | CCR1 | C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (367 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (542 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa) |
| | PPP3R1 | Uncharacterized protein. (189 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (399 aa) |
| | GNB1 | G protein subunit beta 1. (340 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | BCAR1 | BCAR1 scaffold protein, Cas family member. (916 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (521 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | LOC104676775 | Ig-like domain-containing protein; Belongs to the MHC class I family. (391 aa) |
| | GNA11 | G protein subunit alpha 11. (359 aa) |
| | CASP3 | Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (253 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa) |
| | GNAI3 | G protein subunit alpha i3. (354 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (519 aa) |
| | CCL4 | C-C motif chemokine. (92 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | STAT3 | Signal transducer and activator of transcription. (802 aa) |
| | TAP2 | Transporter 2, ATP binding cassette subfamily B member. (723 aa) |
| | CALM3 | Calmodulin 1; Belongs to the calmodulin family. (149 aa) |
| | CCR3 | C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (376 aa) |
| | IRF3 | IRF tryptophan pentad repeat domain-containing protein. (426 aa) |
| | GNAI1 | G protein subunit alpha i1. (253 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa) |
| | ENSRROP00000019822 | Uncharacterized protein; Belongs to the calmodulin family. (141 aa) |
| | SRC | Tyrosine-protein kinase. (540 aa) |
| | PTGER4 | Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa) |
| | PRKCB | Non-specific serine/threonine protein kinase. (590 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | NFATC3 | Nuclear factor of activated T cells 3. (1075 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | IL10RA | Interleukin 10 receptor subunit alpha. (578 aa) |
| | ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1383 aa) |
| | PDIA3 | Protein disulfide-isomerase. (505 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (671 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1114 aa) |
| | CREB3 | cAMP responsive element binding protein 3. (372 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (788 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa) |
| | CRK | CRK proto-oncogene, adaptor protein. (304 aa) |
| | RB1 | RB transcriptional corepressor 1. (929 aa) |
| | PTGER1 | Prostaglandin E receptor 1. (402 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (330 aa) |
| | LOC104664497 | C-C motif chemokine. (71 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (789 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | LOC104676771 | Major histocompatibility complex, class I, F; Belongs to the MHC class I family. (369 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1225 aa) |
| | NFKBIA | ANK_REP_REGION domain-containing protein. (343 aa) |
| | ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa) |
| | IL6R | Interleukin 6 receptor. (468 aa) |
| | FAS | Fas cell surface death receptor. (331 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (520 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | CDKN2A | Cyclin dependent kinase inhibitor 2A. (159 aa) |
| | ARHGEF1 | Rho guanine nucleotide exchange factor 1. (968 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | TAPBP | TAP binding protein. (504 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (461 aa) |
| | E2F1 | E2F transcription factor 1. (485 aa) |
| | GNB5 | G protein subunit beta 5. (403 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | LOC104662055 | EF-hand domain-containing protein; Belongs to the calmodulin family. (75 aa) |
| | PTGER3 | Prostaglandin E receptor 3. (414 aa) |
| | GNG4 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1109 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | TSC1 | TSC complex subunit 1. (1163 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | ELK1 | Uncharacterized protein. (428 aa) |
| | CXCL12 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa) |
| | GNG5 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | GNAQ | G protein subunit alpha q. (359 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2703 aa) |
| | FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (280 aa) |
| | GNB4 | G protein subunit beta 4. (340 aa) |
| | CGAS | Cyclic GMP-AMP synthase. (523 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (421 aa) |
| | ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa) |
| | CREB3L1 | cAMP responsive element binding protein 3 like 1. (519 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1210 aa) |
| | RHEB | Ras homolog, mTORC1 binding. (184 aa) |
| | CX3CL1 | C-X3-C motif chemokine ligand 1. (407 aa) |
| | RAF1 | Uncharacterized protein. (668 aa) |
| | LOC104663799 | Uncharacterized protein. (246 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | GNAS | GNAS complex locus. (1041 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1058 aa) |
| | HLA-E | Major histocompatibility complex, class I, E; Belongs to the MHC class I family. (364 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (932 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) |
| | JAK1 | Tyrosine-protein kinase. (1154 aa) |
| | TSC2 | TSC complex subunit 2. (1807 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | GNB2 | G protein subunit beta 2. (340 aa) |
| | ADCY6 | Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (603 aa) |
| | ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1147 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa) |
| | CALML6 | Calmodulin like 6. (181 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa) |
| | GNG12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | AKAP13 | A-kinase anchoring protein 13. (2874 aa) |
| | GNA12 | G protein subunit alpha 12. (381 aa) |
| | CALR | Calreticulin. (417 aa) |
| | RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (485 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2714 aa) |
| | GNG8 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | STING1 | Transmembrane protein 173. (379 aa) |
| | CREB3L2 | cAMP responsive element binding protein 3 like 2. (520 aa) |
| | CALML4 | Calmodulin like 4. (192 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (975 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (417 aa) |
| | EIF4EBP1 | Eukaryotic translation initiation factor 4E binding protein 1. (118 aa) |
