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| | HLA-DOA | Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa) |
| | CREBBP | CREB binding protein. (2442 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1043 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | IL6 | Interleukin 6. (214 aa) |
| | STAT5A | Signal transducer and activator of transcription. (905 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa) |
| | LTA | Lymphotoxin alpha; Belongs to the tumor necrosis factor family. (205 aa) |
| | CD3D | CD3d molecule. (171 aa) |
| | ATF6B | Activating transcription factor 6 beta. (708 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | ADCY5 | Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (864 aa) |
| | E2F3 | E2F transcription factor 3. (465 aa) |
| | ETS1 | ETS proto-oncogene 1, transcription factor. (485 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | JAK3 | Tyrosine-protein kinase. (1124 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (914 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | ANAPC10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) |
| | IL1R2 | Interleukin 1 receptor type 2. (397 aa) |
| | CD3G | CD3g molecule. (181 aa) |
| | VDAC1 | Voltage dependent anion channel 1. (283 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (197 aa) |
| | ATF4 | Activating transcription factor 4. (351 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (387 aa) |
| | CD4 | CD4 molecule. (458 aa) |
| | NFATC1 | Nuclear factor of activated T cells 1. (895 aa) |
| | RANBP1 | RanBD1 domain-containing protein. (277 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) |
| | ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1075 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | E2F2 | E2F transcription factor 2. (437 aa) |
| | B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa) |
| | CDC20 | Cell division cycle 20. (499 aa) |
| | MAD2L1 | HORMA domain-containing protein. (205 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | IL1R1 | Interleukin 1 receptor type 1. (569 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | STAT5B | Signal transducer and activator of transcription. (787 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | ADCY2 | Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa) |
| | CD3E | CD3e molecule. (198 aa) |
| | DLG1 | Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (926 aa) |
| | LCK | Tyrosine-protein kinase. (561 aa) |
| | POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa) |
| | CCNB2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (398 aa) |
| | RELB | RELB proto-oncogene, NF-kB subunit. (541 aa) |
| | PPP3R1 | Uncharacterized protein. (189 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | KAT2B | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (832 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (399 aa) |
| | ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (812 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (410 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (521 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | LOC104676775 | Ig-like domain-containing protein; Belongs to the MHC class I family. (391 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (410 aa) |
| | TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1132 aa) |
| | ICAM1 | Intercellular adhesion molecule 1. (532 aa) |
| | IL2RA | Interleukin 2 receptor subunit alpha. (272 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (253 aa) |
| | RANBP3 | RAN binding protein 3. (576 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) |
| | CDC26 | Cell division cycle 26. (85 aa) |
| | TCF3 | Transcription factor 3. (655 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | ANAPC5 | Anaphase promoting complex subunit 5. (755 aa) |
| | NFKB2 | Nuclear factor kappa B subunit 2. (899 aa) |
| | SRF | Serum response factor. (508 aa) |
| | CANX | Calnexin. (600 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | NFATC3 | Nuclear factor of activated T cells 3. (1075 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | CDC23 | Cell division cycle 23. (597 aa) |
| | MAP3K14 | Mitogen-activated protein kinase kinase kinase 14. (947 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) |
| | TLN1 | Talin 1. (2562 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) |
| | SLC25A4 | Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | CREB3 | cAMP responsive element binding protein 3. (372 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (465 aa) |
| | TLN2 | Talin 2. (2544 aa) |
| | RB1 | RB transcriptional corepressor 1. (929 aa) |
| | TSPO2 | Translocator protein 2. (170 aa) |
| | ANAPC2 | Anaphase promoting complex subunit 2; Belongs to the cullin family. (822 aa) |
| | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1449 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | XIAP | X-linked inhibitor of apoptosis. (497 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (498 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (330 aa) |
| | VDAC2 | Voltage dependent anion channel 2. (308 aa) |
| | HLA-DPB1 | Major histocompatibility complex, class II, DP beta 1. (258 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (789 aa) |
| | BUB1B | BUB1 N-terminal domain-containing protein. (1073 aa) |
| | NRP1 | Neuropilin; Belongs to the neuropilin family. (923 aa) |
| | LOC104676771 | Major histocompatibility complex, class I, F; Belongs to the MHC class I family. (369 aa) |
| | IL2RG | Fibronectin type-III domain-containing protein. (369 aa) |
| | MSX2 | Msh homeobox 2. (267 aa) |
| | NFKBIA | ANK_REP_REGION domain-containing protein. (343 aa) |
| | ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (520 aa) |
| | TBP | TATA-box binding protein. (333 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | CDKN2A | Cyclin dependent kinase inhibitor 2A. (159 aa) |
| | CDC27 | Uncharacterized protein. (294 aa) |
| | HLA-DOB | Major histocompatibility complex, class II, DO beta. (273 aa) |
| | HLA-DPA1 | Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (305 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | BCL2L1 | BCL2 like 1. (233 aa) |
| | SLC2A1 | Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (506 aa) |
| | LOC104661254 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | NFYB | CBFD_NFYB_HMF domain-containing protein. (208 aa) |
| | CDKN2B | Cyclin dependent kinase inhibitor 2B. (138 aa) |
| | KAT2A | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (806 aa) |
| | EP300 | E1A binding protein p300. (2413 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (550 aa) |
| | SLC25A6 | Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | ITGAL | Integrin subunit alpha L; Belongs to the integrin alpha chain family. (1204 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | ELK4 | ETS transcription factor ELK4. (431 aa) |
| | XPO1 | Exportin 1. (1071 aa) |
| | TRRAP | Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3860 aa) |
| | CRTC2 | CREB regulated transcription coactivator 2. (699 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (461 aa) |
| | FDPS | Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (419 aa) |
| | E2F1 | E2F transcription factor 1. (485 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | LOC104666622 | Ig-like domain-containing protein. (276 aa) |
| | ETS2 | Protein C-ets-2; Transcription factor; Belongs to the ETS family. (469 aa) |
| | ENSRROP00000032491 | RanBD1 domain-containing protein. (183 aa) |
| | CRTC1 | CREB regulated transcription coactivator 1. (608 aa) |
| | TBPL2 | TATA-box binding protein like 2. (376 aa) |
| | HLA-DRA | Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | TBPL1 | TATA-box binding protein like 1. (186 aa) |
| | MSX1 | Msh homeobox 1. (261 aa) |
| | CRTC3 | CREB regulated transcription coactivator 3. (619 aa) |
| | MAP3K3 | Mitogen-activated protein kinase kinase kinase 3. (647 aa) |
| | TSPO | Translocator protein. (169 aa) |
| | GPS2 | G protein pathway suppressor 2. (327 aa) |
| | ELK1 | Uncharacterized protein. (428 aa) |
| | CCND3 | Cyclin D3; Belongs to the cyclin family. (292 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa) |
| | CREB3L1 | cAMP responsive element binding protein 3 like 1. (519 aa) |
| | LTBR | Lymphotoxin beta receptor. (461 aa) |
| | ZFP36 | ZFP36 ring finger protein. (332 aa) |
| | CSF2 | Colony stimulating factor 2. (144 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | EGR2 | Early growth response 2. (476 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa) |
| | HLA-E | Major histocompatibility complex, class I, E; Belongs to the MHC class I family. (364 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (932 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa) |
| | CDC16 | Cell division cycle 16. (620 aa) |
| | ESPL1 | Extra spindle pole bodies like 1, separase. (2120 aa) |
| | JAK1 | Tyrosine-protein kinase. (1154 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | ADCY6 | Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (603 aa) |
| | VAC14 | VAC14 component of PIKFYVE complex. (782 aa) |
| | ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1147 aa) |
| | CDKN2C | Cyclin dependent kinase inhibitor 2C. (168 aa) |
| | BUB3 | WD_REPEATS_REGION domain-containing protein. (328 aa) |
| | MAD1L1 | Mitotic arrest deficient 1 like 1. (718 aa) |
| | VDAC3 | Uncharacterized protein. (284 aa) |
| | IL2RB | Interleukin 2 receptor subunit beta. (551 aa) |
| | ENSRROP00000042033 | GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (220 aa) |
| | ITGB2 | Integrin beta. (769 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (541 aa) |
| | PTTG1 | Uncharacterized protein. (202 aa) |
| | MMP7 | Matrix metallopeptidase 7. (270 aa) |
| | ANAPC7 | Anaphase promoting complex subunit 7. (599 aa) |
| | CALR | Calreticulin. (417 aa) |
| | FOSL1 | FOS like 1, AP-1 transcription factor subunit. (271 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa) |
| | CREB3L2 | cAMP responsive element binding protein 3 like 2. (520 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (975 aa) |
| | SPI1 | Spi-1 proto-oncogene. (270 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (417 aa) |
