STRINGSTRING
PLA2G4F PLA2G4F HIF1A HIF1A PDGFB PDGFB PLD1-2 PLD1-2 AKT1 AKT1 PCYT1B PCYT1B PDPK1 PDPK1 WASF2 WASF2 PIP5K1A PIP5K1A CHKA CHKA MAPK8 MAPK8 DGKA DGKA MAPK9 MAPK9 WASF1 WASF1 GPCPD1 GPCPD1 SP1 SP1 DGKH DGKH PIK3CA PIK3CA DGKQ DGKQ PIK3CD PIK3CD SLC44A4 SLC44A4 PLA2G4A PLA2G4A SOS1 SOS1 MAP2K2 MAP2K2 SLC22A4 SLC22A4 PDGFA PDGFA PIP5K1C PIP5K1C PLPP2 PLPP2 PCYT1A PCYT1A PRKCG PRKCG NRAS NRAS DGKG DGKG SLC5A7 SLC5A7 PRKCB PRKCB PIP5K1B PIP5K1B MAP2K1 MAP2K1 PLA2G4D PLA2G4D SLC22A1 SLC22A1 AKT3 AKT3 PIK3R1 PIK3R1 PDGFD PDGFD EGF EGF SLC22A3 SLC22A3 SLC22A5 SLC22A5 ENSRROP00000024190 ENSRROP00000024190 MAPK1 MAPK1 PLCG1 PLCG1 MTOR MTOR SOS2 SOS2 LYPLA1 LYPLA1 PLA2G4E PLA2G4E PDGFRA PDGFRA PLA2G4B PLA2G4B MAPK10 MAPK10 SLC22A2 SLC22A2 FOS FOS ENSRROP00000029532 ENSRROP00000029532 PIK3R3 PIK3R3 CHPT1 CHPT1 RALGDS RALGDS DGKK DGKK MAPK3 MAPK3 PLPP1 PLPP1 KRAS KRAS TSC1 TSC1 GRB2 GRB2 PDGFC PDGFC RPS6KB1 RPS6KB1 WAS WAS HRAS HRAS RGL4 RGL4 EGFR EGFR RHEB RHEB RAF1 RAF1 PDGFRB PDGFRB PLA2G4C PLA2G4C PLD2 PLD2 SLC44A1 SLC44A1 RAC2 RAC2 PLPP3 PLPP3 CHKB CHKB DGKD DGKD TSC2 TSC2 AKT2 AKT2 SLC44A5 SLC44A5 SLC44A3 SLC44A3 DGKB DGKB DGKZ DGKZ PRKCA PRKCA RPS6KB2 RPS6KB2 PIK3CB PIK3CB EIF4EBP1 EIF4EBP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLA2G4FPhospholipase A2. (849 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (826 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
PLD1-2Uncharacterized protein. (57 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PCYT1BPhosphate cytidylyltransferase 1, choline, beta. (369 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (356 aa)
WASF2WASP family member 2. (498 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (562 aa)
CHKACholine kinase alpha. (422 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
DGKADiacylglycerol kinase. (749 aa)
MAPK9Mitogen-activated protein kinase. (387 aa)
WASF1WASP family member 1. (559 aa)
GPCPD1Glycerophosphocholine phosphodiesterase 1. (672 aa)
SP1Sp1 transcription factor. (786 aa)
DGKHDiacylglycerol kinase. (1156 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
DGKQDiacylglycerol kinase. (847 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
SLC44A4Solute carrier family 44 member 4; Belongs to the CTL (choline transporter-like) family. (737 aa)
PLA2G4APhospholipase A2. (749 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (399 aa)
SLC22A4Solute carrier family 22 member 4. (551 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (169 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (700 aa)
PLPP2Phospholipid phosphatase 2. (308 aa)
PCYT1APhosphate cytidylyltransferase 1, choline, alpha. (381 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
DGKGDiacylglycerol kinase. (791 aa)
SLC5A7Solute carrier family 5 member 7; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (580 aa)
PRKCBNon-specific serine/threonine protein kinase. (590 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (540 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
PLA2G4DPhospholipase A2. (816 aa)
SLC22A1Solute carrier family 22 member 1. (554 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PDGFDPlatelet derived growth factor D. (364 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1233 aa)
SLC22A3Solute carrier family 22 member 3. (560 aa)
SLC22A5Solute carrier family 22 member 5. (581 aa)
ENSRROP00000024190Protein kinase domain-containing protein. (137 aa)
MAPK1Mitogen-activated protein kinase. (330 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1303 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
LYPLA1Lysophospholipase 1. (230 aa)
PLA2G4EPhospholipase A2. (869 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
PLA2G4BPhospholipase A2. (798 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
SLC22A2Solute carrier family 22 member 2. (555 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
ENSRROP00000029532Abhydrolase_2 domain-containing protein. (145 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
CHPT1Choline phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (406 aa)
RALGDSUncharacterized protein. (919 aa)
DGKKDiacylglycerol kinase kappa. (887 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
PLPP1Phospholipid phosphatase 1. (285 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
TSC1TSC complex subunit 1. (1163 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
WASWASP actin nucleation promoting factor. (500 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
RGL4Ral guanine nucleotide dissociation stimulator like 4. (471 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
RHEBRas homolog, mTORC1 binding. (184 aa)
RAF1Uncharacterized protein. (668 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
PLA2G4CPhospholipase A2 group IVC. (551 aa)
PLD2Phospholipase. (933 aa)
SLC44A1Solute carrier family 44 member 1; Belongs to the CTL (choline transporter-like) family. (658 aa)
RAC2Rac family small GTPase 2. (192 aa)
PLPP3acidPPc domain-containing protein. (326 aa)
CHKBCholine kinase beta. (395 aa)
DGKDDiacylglycerol kinase. (1175 aa)
TSC2TSC complex subunit 2. (1807 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
SLC44A5Solute carrier family 44 member 5; Belongs to the CTL (choline transporter-like) family. (685 aa)
SLC44A3Solute carrier family 44 member 3; Belongs to the CTL (choline transporter-like) family. (653 aa)
DGKBDiacylglycerol kinase beta. (429 aa)
DGKZDiacylglycerol kinase. (1152 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (485 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (118 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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