STRINGSTRING
HLA-DOA HLA-DOA IL6 IL6 CD80 CD80 IL1A IL1A KIR3DL3 KIR3DL3 TNF TNF LOC104681114 LOC104681114 CD86 CD86 IL2 IL2 KLRD1 KLRD1 LOC104676775 LOC104676775 IFNG IFNG HLA-DPB1 HLA-DPB1 LOC104676771 LOC104676771 FAS FAS HLA-DOB HLA-DOB HLA-DPA1 HLA-DPA1 PRF1 PRF1 LOC104675306 LOC104675306 LOC104666622 LOC104666622 HLA-DRA HLA-DRA IL1B IL1B FASLG FASLG KLRC1 KLRC1 HLA-E HLA-E GZMB GZMB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa)
IL6Interleukin 6. (214 aa)
CD80CD80 molecule. (288 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (271 aa)
KIR3DL3Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3. (428 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
LOC104681114Uncharacterized protein. (189 aa)
CD86CD86 molecule. (329 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
KLRD1Killer cell lectin like receptor D1. (179 aa)
LOC104676775Ig-like domain-containing protein; Belongs to the MHC class I family. (391 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa)
HLA-DPB1Major histocompatibility complex, class II, DP beta 1. (258 aa)
LOC104676771Major histocompatibility complex, class I, F; Belongs to the MHC class I family. (369 aa)
FASFas cell surface death receptor. (331 aa)
HLA-DOBMajor histocompatibility complex, class II, DO beta. (273 aa)
HLA-DPA1Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (305 aa)
PRF1Perforin 1. (555 aa)
LOC104675306Ig-like domain-containing protein. (347 aa)
LOC104666622Ig-like domain-containing protein. (276 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (280 aa)
KLRC1Killer cell lectin like receptor C1. (233 aa)
HLA-EMajor histocompatibility complex, class I, E; Belongs to the MHC class I family. (364 aa)
GZMBGranzyme B; Belongs to the peptidase S1 family. (281 aa)
Your Current Organism:
Rhinopithecus roxellana
NCBI taxonomy Id: 61622
Other names: Pygathrix roxellana, R. roxellana, golden snub-nosed monkey
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