STRINGSTRING
MCM7 MCM7 A0A3Q0KEL0 A0A3Q0KEL0 A0A3Q0KG44 A0A3Q0KG44 A0A3Q0KI59 A0A3Q0KI59 A0A3Q0KJA1 A0A3Q0KJA1 A0A3Q0KP41 A0A3Q0KP41 A0A3Q0KPC0 A0A3Q0KPC0 A0A3Q0KS76 A0A3Q0KS76 A0A3Q0KT28 A0A3Q0KT28 A0A3Q0KTJ7 A0A3Q0KTJ7 A0A3Q0KUC0 A0A3Q0KUC0 A0A5K4EC46 A0A5K4EC46 A0A5K4ECP8 A0A5K4ECP8 A0A5K4F145 A0A5K4F145 A0A5K4F300 A0A5K4F300 Smp_079560 Smp_079560 Smp_143490 Smp_143490 Smp_052390 Smp_052390 Smp_042210 Smp_042210
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (771 aa)
A0A3Q0KEL0DNA helicase; Belongs to the MCM family. (820 aa)
A0A3Q0KG44DNA helicase; Belongs to the MCM family. (894 aa)
A0A3Q0KI59DBF4-type domain-containing protein. (566 aa)
A0A3Q0KJA1DNA helicase; Belongs to the MCM family. (806 aa)
A0A3Q0KP41Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (524 aa)
A0A3Q0KPC0Mcm10 domain-containing protein. (974 aa)
A0A3Q0KS76Ris2 protein, putative. (577 aa)
A0A3Q0KT28DNA helicase; Belongs to the MCM family. (898 aa)
A0A3Q0KTJ7Serine/threonine kinase. (526 aa)
A0A3Q0KUC0Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (569 aa)
A0A5K4EC46DNA replication licensing factor MCM7. (746 aa)
A0A5K4ECP8DNA helicase. (802 aa)
A0A5K4F145Uncharacterized protein. (421 aa)
A0A5K4F300Uncharacterized protein. (912 aa)
Smp_079560Putative DNA replication licensing factor MCM2. (503 aa)
Smp_143490DNA helicase; Belongs to the MCM family. (750 aa)
Smp_052390Putative origin recognition complex subunit. (485 aa)
Smp_042210Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (488 aa)
Your Current Organism:
Schistosoma mansoni
NCBI taxonomy Id: 6183
Other names: S. mansoni
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