21 items (Schistosoma mansoni) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	A0A3Q0KC36	Putative adenosine kinase. (341 aa)
	A0A3Q0KC34	Putative adenosine kinase. (341 aa)
	A0A3Q0KG30	Putative adenine phosphoribosyltransferase. (116 aa)
	A0A3Q0KJY0	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (231 aa)
	A0A3Q0KPJ1	Hypoxanthine-guanine phosphoribosyltransferase,putative. (227 aa)
	A0A3Q0KU65	Purine nucleoside phosphorylase. (214 aa)
	A0A5K4EK44	Hypoxanthine phosphoribosyltransferase. (225 aa)
	A0A5K4EWY8	Purine nucleoside phosphorylase. (67 aa)
	A0A5K4EWZ0	Purine nucleoside phosphorylase. (320 aa)
	A0A5K4EY01	S-methyl-5'-thioadenosine phosphorylase. (295 aa)
	A0A5K4EY11	Purine nucleoside phosphorylase. (260 aa)
	A0A5K4F3L4	Uncharacterized protein. (279 aa)
	A0A5K4F407	Purine nucleoside phosphorylase. (287 aa)
	A0A5K4F8A3	Uncharacterized protein. (226 aa)
	Smp_168500	Hypoxanthine-guanine phosphoribosyltransferase,putative. (228 aa)
	Smp_171620	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (299 aa)
	Smp_151260	Putative adenine phosphoribosyltransferase. (142 aa)
	Smp_054410	Putative adenine phosphoribosyltransferase. (196 aa)
	Smp_054360	Putative adenine phosphoribosyltransferase. (186 aa)
	I0B503_SCHMA	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (299 aa)
	HGPRT	Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). (284 aa)

Your Current Organism:

Schistosoma mansoni

NCBI taxonomy Id: 6183
Other names: S. mansoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A3Q0KC34	A0A3Q0KC36	A0A3Q0KC34	A0A3Q0KC36	Putative adenosine kinase.	Putative adenosine kinase.	0.903
A0A3Q0KC34	A0A3Q0KG30	A0A3Q0KC34	A0A3Q0KG30	Putative adenosine kinase.	Putative adenine phosphoribosyltransferase.	0.561
A0A3Q0KC34	A0A3Q0KU65	A0A3Q0KC34	A0A3Q0KU65	Putative adenosine kinase.	Purine nucleoside phosphorylase.	0.651
A0A3Q0KC34	A0A5K4EWY8	A0A3Q0KC34	A0A5K4EWY8	Putative adenosine kinase.	Purine nucleoside phosphorylase.	0.651
A0A3Q0KC34	A0A5K4EWZ0	A0A3Q0KC34	A0A5K4EWZ0	Putative adenosine kinase.	Purine nucleoside phosphorylase.	0.963
A0A3Q0KC34	A0A5K4EY01	A0A3Q0KC34	A0A5K4EY01	Putative adenosine kinase.	S-methyl-5'-thioadenosine phosphorylase.	0.485
A0A3Q0KC34	A0A5K4EY11	A0A3Q0KC34	A0A5K4EY11	Putative adenosine kinase.	Purine nucleoside phosphorylase.	0.651
A0A3Q0KC34	A0A5K4F3L4	A0A3Q0KC34	A0A5K4F3L4	Putative adenosine kinase.	Uncharacterized protein.	0.504
A0A3Q0KC34	A0A5K4F407	A0A3Q0KC34	A0A5K4F407	Putative adenosine kinase.	Purine nucleoside phosphorylase.	0.963
A0A3Q0KC34	I0B503_SCHMA	A0A3Q0KC34	I0B503	Putative adenosine kinase.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.741
A0A3Q0KC34	Smp_054360	A0A3Q0KC34	G4VQJ4	Putative adenosine kinase.	Putative adenine phosphoribosyltransferase.	0.975
A0A3Q0KC34	Smp_054410	A0A3Q0KC34	G4VQJ3	Putative adenosine kinase.	Putative adenine phosphoribosyltransferase.	0.975
A0A3Q0KC34	Smp_151260	A0A3Q0KC34	G4VQJ2	Putative adenosine kinase.	Putative adenine phosphoribosyltransferase.	0.975
A0A3Q0KC34	Smp_171620	A0A3Q0KC34	G4VP86	Putative adenosine kinase.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.727
A0A3Q0KC36	A0A3Q0KC34	A0A3Q0KC36	A0A3Q0KC34	Putative adenosine kinase.	Putative adenosine kinase.	0.903
A0A3Q0KC36	A0A3Q0KG30	A0A3Q0KC36	A0A3Q0KG30	Putative adenosine kinase.	Putative adenine phosphoribosyltransferase.	0.561
A0A3Q0KC36	A0A3Q0KU65	A0A3Q0KC36	A0A3Q0KU65	Putative adenosine kinase.	Purine nucleoside phosphorylase.	0.651
A0A3Q0KC36	A0A5K4EWY8	A0A3Q0KC36	A0A5K4EWY8	Putative adenosine kinase.	Purine nucleoside phosphorylase.	0.651
A0A3Q0KC36	A0A5K4EWZ0	A0A3Q0KC36	A0A5K4EWZ0	Putative adenosine kinase.	Purine nucleoside phosphorylase.	0.963
A0A3Q0KC36	A0A5K4EY01	A0A3Q0KC36	A0A5K4EY01	Putative adenosine kinase.	S-methyl-5'-thioadenosine phosphorylase.	0.485