STRINGSTRING
A0A5K4ERX3 A0A5K4ERX3 A0A5K4EYZ8 A0A5K4EYZ8 A0A5K4EZW4 A0A5K4EZW4 A0A5K4F2D0 A0A5K4F2D0 A0A5K4F9K2 A0A5K4F9K2 A0A5K4FAI1 A0A5K4FAI1 A0A5K4FGR5 A0A5K4FGR5 Smp_079050.1 Smp_079050.1 A0A3Q0KEL0 A0A3Q0KEL0 MCM7 MCM7 A0A3Q0KD20 A0A3Q0KD20 A0A3Q0KD12 A0A3Q0KD12 Smp_079560 Smp_079560 Smp_143490 Smp_143490 Smp_007000 Smp_007000 Smp_009030 Smp_009030 Smp_042210 Smp_042210 A0A3Q0KEZ9 A0A3Q0KEZ9 A0A3Q0KFE4 A0A3Q0KFE4 A0A3Q0KFF1 A0A3Q0KFF1 A0A3Q0KG44 A0A3Q0KG44 A0A3Q0KH66 A0A3Q0KH66 A0A3Q0KIQ0 A0A3Q0KIQ0 A0A3Q0KJA1 A0A3Q0KJA1 A0A3Q0KJT4 A0A3Q0KJT4 A0A3Q0KKE1 A0A3Q0KKE1 A0A3Q0KKQ9 A0A3Q0KKQ9 A0A3Q0KPH9 A0A3Q0KPH9 A0A3Q0KPJ4 A0A3Q0KPJ4 A0A3Q0KR94 A0A3Q0KR94 A0A3Q0KT28 A0A3Q0KT28 A0A3Q0KUC0 A0A3Q0KUC0 A0A3Q0KVK7 A0A3Q0KVK7 A0A5K4EC46 A0A5K4EC46 A0A5K4ECP8 A0A5K4ECP8 A0A5K4EKF4 A0A5K4EKF4 A0A3Q0KEZ6 A0A3Q0KEZ6 A0A5K4EKN5 A0A5K4EKN5 A0A5K4EL72 A0A5K4EL72 A0A5K4EQS9 A0A5K4EQS9 A0A5K4ER62 A0A5K4ER62
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A5K4ERX3DNA ligase. (534 aa)
A0A5K4EYZ8DNA polymerase. (2282 aa)
A0A5K4EZW4DNA polymerase. (336 aa)
A0A5K4F2D0DNA polymerase. (1644 aa)
A0A5K4F9K2Uncharacterized protein. (388 aa)
A0A5K4FAI1Uncharacterized protein. (2165 aa)
A0A5K4FGR5Uncharacterized protein. (219 aa)
Smp_079050.1DNA primase large subunit, putative. (515 aa)
A0A3Q0KEL0DNA helicase; Belongs to the MCM family. (820 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (771 aa)
A0A3Q0KD20DNA ligase. (843 aa)
A0A3Q0KD12DNA ligase. (840 aa)
Smp_079560Putative DNA replication licensing factor MCM2. (503 aa)
Smp_143490DNA helicase; Belongs to the MCM family. (750 aa)
Smp_007000Putative partner of sld5. (212 aa)
Smp_009030Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (837 aa)
Smp_042210Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (488 aa)
A0A3Q0KEZ9DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (226 aa)
A0A3Q0KFE4Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
A0A3Q0KFF1Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (238 aa)
A0A3Q0KG44DNA helicase; Belongs to the MCM family. (894 aa)
A0A3Q0KH66DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (675 aa)
A0A3Q0KIQ0DNA polymerase. (1259 aa)
A0A3Q0KJA1DNA helicase; Belongs to the MCM family. (806 aa)
A0A3Q0KJT4DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (198 aa)
A0A3Q0KKE1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (590 aa)
A0A3Q0KKQ9DNA polymerase epsilon subunit 2. (343 aa)
A0A3Q0KPH9DNA ligase. (606 aa)
A0A3Q0KPJ4FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (685 aa)
A0A3Q0KR94DNA primase; Belongs to the eukaryotic-type primase small subunit family. (448 aa)
A0A3Q0KT28DNA helicase; Belongs to the MCM family. (898 aa)
A0A3Q0KUC0Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (569 aa)
A0A3Q0KVK7DNA polymerase. (2582 aa)
A0A5K4EC46DNA replication licensing factor MCM7. (746 aa)
A0A5K4ECP8DNA helicase. (802 aa)
A0A5K4EKF4DNA polymerase epsilon subunit 2. (622 aa)
A0A3Q0KEZ6DNA replication complex GINS protein SLD5. (163 aa)
A0A5K4EKN5Replication protein A subunit. (555 aa)
A0A5K4EL72DNA polymerase epsilon subunit 2. (626 aa)
A0A5K4EQS9DNA ligase. (1098 aa)
A0A5K4ER62DNA ligase. (371 aa)
Your Current Organism:
Schistosoma mansoni
NCBI taxonomy Id: 6183
Other names: S. mansoni
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