26 items (Schistosoma mansoni) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	A0A5K4EM38	Putative glutamate synthase. (184 aa)
	A0A5K4EL52	Putative glutamate synthase. (2159 aa)
	A0A5K4EI03	Uncharacterized protein. (250 aa)
	A0A3Q0KVK7	DNA polymerase. (2582 aa)
	A0A3Q0KL96	Putative glutamate synthase. (1909 aa)
	Smp_006550.1	Putative glutaredoxin, grx. (216 aa)
	NTH1	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (260 aa)
	Smp_092490.1	Putative nadh-plastoquinone oxidoreductase; Belongs to the complex I 20 kDa subunit family. (207 aa)
	A0A3Q0KKV0	Adrenodoxin, putative. (93 aa)
	A0A3Q0KJ01	Putative molybdopterin cofactor synthesis protein A. (244 aa)
	A0A3Q0KIQ0	DNA polymerase. (1259 aa)
	A0A3Q0KGR3	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (777 aa)
	A0A3Q0KCS8	Uncharacterized protein. (112 aa)
	A0A3Q0KC95	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (475 aa)
	A0A3Q0KC81	Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (410 aa)
	Smp_069770	Putative nadh-ubiquinone oxidoreductase 24 kD subunit. (248 aa)
	A0A5K4EM75	Putative glutamate synthase. (1892 aa)
	A0A5K4EYZ8	DNA polymerase. (2282 aa)
	A0A5K4EZW4	DNA polymerase. (336 aa)
	A0A5K4F123	Uncharacterized protein. (183 aa)
	A0A5K4F2D0	DNA polymerase. (1644 aa)
	Smp_207000	Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...] (272 aa)
	Smp_010100	Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family. (410 aa)
	Smp_079050.1	DNA primase large subunit, putative. (515 aa)
	Smp_124940	Adrenodoxin, putative. (158 aa)
	Smp_085500	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (563 aa)

Your Current Organism:

Schistosoma mansoni

NCBI taxonomy Id: 6183
Other names: S. mansoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A3Q0KC81	A0A3Q0KGR3	A0A3Q0KC81	A0A3Q0KGR3	Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	0.655
A0A3Q0KC81	A0A5K4F123	A0A3Q0KC81	A0A5K4F123	Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	Uncharacterized protein.	0.427
A0A3Q0KC81	Smp_006550.1	A0A3Q0KC81	G4V9X6	Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	Putative glutaredoxin, grx.	0.412
A0A3Q0KC81	Smp_207000	A0A3Q0KC81	C4PYP8	Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...]	0.608
A0A3Q0KC95	A0A3Q0KCS8	A0A3Q0KC95	A0A3Q0KCS8	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.	Uncharacterized protein.	0.728
A0A3Q0KC95	A0A3Q0KGR3	A0A3Q0KC95	A0A3Q0KGR3	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	0.980
A0A3Q0KC95	A0A3Q0KKV0	A0A3Q0KC95	A0A3Q0KKV0	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.	Adrenodoxin, putative.	0.728
A0A3Q0KC95	A0A5K4EI03	A0A3Q0KC95	A0A5K4EI03	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.	Uncharacterized protein.	0.999
A0A3Q0KC95	Smp_069770	A0A3Q0KC95	G4VK53	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.	Putative nadh-ubiquinone oxidoreductase 24 kD subunit.	0.999
A0A3Q0KC95	Smp_092490.1	A0A3Q0KC95	G4V5Q1	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.	Putative nadh-plastoquinone oxidoreductase; Belongs to the complex I 20 kDa subunit family.	0.999
A0A3Q0KC95	Smp_124940	A0A3Q0KC95	G4LZ25	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.	Adrenodoxin, putative.	0.728
A0A3Q0KCS8	A0A3Q0KC95	A0A3Q0KCS8	A0A3Q0KC95	Uncharacterized protein.	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.	0.728
A0A3Q0KCS8	A0A3Q0KGR3	A0A3Q0KCS8	A0A3Q0KGR3	Uncharacterized protein.	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	0.408
A0A3Q0KCS8	A0A3Q0KL96	A0A3Q0KCS8	A0A3Q0KL96	Uncharacterized protein.	Putative glutamate synthase.	0.467
A0A3Q0KCS8	A0A5K4EL52	A0A3Q0KCS8	A0A5K4EL52	Uncharacterized protein.	Putative glutamate synthase.	0.467
A0A3Q0KCS8	A0A5K4EM38	A0A3Q0KCS8	A0A5K4EM38	Uncharacterized protein.	Putative glutamate synthase.	0.467
A0A3Q0KCS8	A0A5K4EM75	A0A3Q0KCS8	A0A5K4EM75	Uncharacterized protein.	Putative glutamate synthase.	0.467
A0A3Q0KCS8	Smp_069770	A0A3Q0KCS8	G4VK53	Uncharacterized protein.	Putative nadh-ubiquinone oxidoreductase 24 kD subunit.	0.609
A0A3Q0KCS8	Smp_092490.1	A0A3Q0KCS8	G4V5Q1	Uncharacterized protein.	Putative nadh-plastoquinone oxidoreductase; Belongs to the complex I 20 kDa subunit family.	0.814
A0A3Q0KGR3	A0A3Q0KC81	A0A3Q0KGR3	A0A3Q0KC81	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	0.655