STRINGSTRING
A0A3Q0KPT7 A0A3Q0KPT7 A0A3Q0KB89 A0A3Q0KB89 A0A3Q0KB90 A0A3Q0KB90 A0A3Q0KB92 A0A3Q0KB92 A0A3Q0KD12 A0A3Q0KD12 A0A3Q0KD20 A0A3Q0KD20 A0A3Q0KDL7 A0A3Q0KDL7 MCM7 MCM7 A0A3Q0KE53 A0A3Q0KE53 A0A3Q0KEK7 A0A3Q0KEK7 A0A3Q0KEL0 A0A3Q0KEL0 A0A3Q0KEZ6 A0A3Q0KEZ6 A0A3Q0KEZ9 A0A3Q0KEZ9 A0A3Q0KF02 A0A3Q0KF02 A0A3Q0KFE4 A0A3Q0KFE4 A0A3Q0KFF1 A0A3Q0KFF1 A0A3Q0KFF6 A0A3Q0KFF6 A0A3Q0KFF7 A0A3Q0KFF7 A0A3Q0KG44 A0A3Q0KG44 A0A3Q0KGQ2 A0A3Q0KGQ2 A0A3Q0KH24 A0A3Q0KH24 A0A3Q0KH66 A0A3Q0KH66 A0A3Q0KH81 A0A3Q0KH81 A0A3Q0KHT5 A0A3Q0KHT5 A0A3Q0KI59 A0A3Q0KI59 A0A3Q0KIQ0 A0A3Q0KIQ0 A0A3Q0KJA1 A0A3Q0KJA1 A0A3Q0KJT4 A0A3Q0KJT4 A0A3Q0KKA3 A0A3Q0KKA3 A0A3Q0KKE1 A0A3Q0KKE1 A0A3Q0KKQ9 A0A3Q0KKQ9 A0A3Q0KKZ0 A0A3Q0KKZ0 A0A3Q0KL39 A0A3Q0KL39 A0A3Q0KM78 A0A3Q0KM78 A0A3Q0KMQ1 A0A3Q0KMQ1 A0A3Q0KN76 A0A3Q0KN76 A0A3Q0KP41 A0A3Q0KP41 A0A3Q0KPC0 A0A3Q0KPC0 A0A3Q0KPR6 A0A3Q0KPR6 A0A3Q0KPX8 A0A3Q0KPX8 A0A3Q0KQ30 A0A3Q0KQ30 A0A3Q0KQH2 A0A3Q0KQH2 A0A3Q0KR94 A0A3Q0KR94 A0A3Q0KS76 A0A3Q0KS76 A0A3Q0KT28 A0A3Q0KT28 A0A3Q0KT73 A0A3Q0KT73 A0A3Q0KTJ7 A0A3Q0KTJ7 A0A3Q0KTX5 A0A3Q0KTX5 A0A3Q0KUC0 A0A3Q0KUC0 A0A3Q0KUF6 A0A3Q0KUF6 A0A3Q0KUH5 A0A3Q0KUH5 A0A3Q0KV11 A0A3Q0KV11 A0A3Q0KVA6 A0A3Q0KVA6 A0A3Q0KVK3 A0A3Q0KVK3 A0A3Q0KVK7 A0A3Q0KVK7 A0A5K4E9T2 A0A5K4E9T2 A0A5K4E9Z6 A0A5K4E9Z6 A0A5K4EAG2 A0A5K4EAG2 A0A5K4EAI9 A0A5K4EAI9 A0A5K4EC46 A0A5K4EC46 A0A5K4ECP8 A0A5K4ECP8 A0A5K4EDH5 A0A5K4EDH5 A0A5K4EDX8 A0A5K4EDX8 A0A5K4EKF4 A0A5K4EKF4 A0A5K4EKM7 A0A5K4EKM7 A0A5K4EKN5 A0A5K4EKN5 A0A5K4EL72 A0A5K4EL72 A0A5K4ELI1 A0A5K4ELI1 A0A5K4ELP7 A0A5K4ELP7 A0A5K4ENB7 A0A5K4ENB7 A0A5K4ERM7 A0A5K4ERM7 A0A5K4ESG5 A0A5K4ESG5 A0A5K4EYZ8 A0A5K4EYZ8 A0A5K4EZH3 A0A5K4EZH3 A0A5K4EZW4 A0A5K4EZW4 A0A5K4F079 A0A5K4F079 A0A5K4F0I6 A0A5K4F0I6 A0A5K4F0M9 A0A5K4F0M9 A0A5K4F0P7 A0A5K4F0P7 A0A5K4F145 A0A5K4F145 A0A5K4F1C0 A0A5K4F1C0 A0A5K4F230 A0A5K4F230 A0A5K4F2D0 A0A5K4F2D0 A0A5K4F2T7 A0A5K4F2T7 A0A5K4F300 A0A5K4F300 A0A5K4F814 A0A5K4F814 A0A5K4F861 A0A5K4F861 A0A5K4F8X3 A0A5K4F8X3 A0A5K4F9B0 A0A5K4F9B0 A0A5K4F9I1 A0A5K4F9I1 A0A5K4F9K2 A0A5K4F9K2 A0A5K4FB35 A0A5K4FB35 A0A5K4FBL9 A0A5K4FBL9 A0A5K4FCG6 A0A5K4FCG6 A0A5K4FCI3 A0A5K4FCI3 A0A5K4FGR5 A0A5K4FGR5 RPT4 RPT4 PA28-gamma PA28-gamma Smp_108390 Smp_108390 Smp_053300 Smp_053300 Smp_079050.1 Smp_079050.1 Smp_089430 Smp_089430 Smp_178810 Smp_178810 Smp_182600 Smp_182600 Smp_121430.2 Smp_121430.2 Smp_085310.1 Smp_085310.1 Smp_028430 Smp_028430 Smp_026630 Smp_026630 Smp_058650 Smp_058650 c8190_g2_i1 c8190_g2_i1 Smp_096360 Smp_096360 Smp_056500 Smp_056500 Smp_076230 Smp_076230 Smp_042270.2 Smp_042270.2 Smp_070930 Smp_070930 Smp_047740 Smp_047740 Smp_036220 Smp_036220 Smp_076660 Smp_076660 Smp_079560 Smp_079560 Smp_034490 Smp_034490 Smp_012470 Smp_012470 Smp_072340 Smp_072340 Smp_025800 Smp_025800 Smp_047610 Smp_047610 Smp_143490 Smp_143490 Smp_007000 Smp_007000 Smp_052390 Smp_052390 Smp_052870 Smp_052870 Smp_052910 Smp_052910 Smp_066340.1 Smp_066340.1 Smp_151480 Smp_151480 Smp_038080.1 Smp_038080.1 Smp_052460 Smp_052460 Smp_092280 Smp_092280 Smp_050820 Smp_050820 Smp_042210 Smp_042210 Smp_064320.1 Smp_064320.1 Smp_051010 Smp_051010 Smp_077790 Smp_077790 Smp_073410 Smp_073410 Smp_017070 Smp_017070 SmPOH SmPOH PSMD4_SCHMA PSMD4_SCHMA Smp_017280 Smp_017280
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A3Q0KPT7Putative DNA replication licensing factor MCM1; Belongs to the MCM family. (909 aa)
A0A3Q0KB8926S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (995 aa)
A0A3Q0KB9026s proteasome regulatory particle subunit,putative. (245 aa)
A0A3Q0KB9226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (734 aa)
A0A3Q0KD12DNA ligase. (840 aa)
A0A3Q0KD20DNA ligase. (843 aa)
A0A3Q0KDL726S proteasome non-ATPase regulatory subunit 7 (M67 family). (349 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (771 aa)
A0A3Q0KE53Proteasome subunit alpha type. (254 aa)
A0A3Q0KEK7Putative cell division cycle. (802 aa)
A0A3Q0KEL0DNA helicase; Belongs to the MCM family. (820 aa)
A0A3Q0KEZ6DNA replication complex GINS protein SLD5. (163 aa)
A0A3Q0KEZ9DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (226 aa)
A0A3Q0KF0226S protease regulatory subunit 6a, putative; Belongs to the AAA ATPase family. (412 aa)
A0A3Q0KFE4Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
A0A3Q0KFF1Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (238 aa)
A0A3Q0KFF6Putative ubiquitin (Ribosomal protein L40). (609 aa)
A0A3Q0KFF7Histone-like transcription factor ccaat-related. (110 aa)
A0A3Q0KG44DNA helicase; Belongs to the MCM family. (894 aa)
A0A3Q0KGQ226S proteasome subunit S9, putative. (415 aa)
A0A3Q0KH24Putative replication factor C / DNA polymerase III gamma-tau subunit. (323 aa)
A0A3Q0KH66DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (675 aa)
A0A3Q0KH81Proteasome subunit alpha type. (235 aa)
A0A3Q0KHT5Proteasome subunit beta. (193 aa)
A0A3Q0KI59DBF4-type domain-containing protein. (566 aa)
A0A3Q0KIQ0DNA polymerase. (1259 aa)
A0A3Q0KJA1DNA helicase; Belongs to the MCM family. (806 aa)
A0A3Q0KJT4DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (198 aa)
A0A3Q0KKA3Putative 26s protease regulatory subunit; Belongs to the AAA ATPase family. (430 aa)
A0A3Q0KKE1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (590 aa)
A0A3Q0KKQ9DNA polymerase epsilon subunit 2. (343 aa)
A0A3Q0KKZ0Uncharacterized protein. (544 aa)
A0A3Q0KL39Uncharacterized protein. (2794 aa)
A0A3Q0KM78Putative cell division cycle. (1104 aa)
A0A3Q0KMQ1AAA domain-containing protein. (931 aa)
A0A3Q0KN76Putative replication factor C / DNA polymerase III gamma-tau subunit. (318 aa)
A0A3Q0KP41Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (524 aa)
A0A3Q0KPC0Mcm10 domain-containing protein. (974 aa)
A0A3Q0KPR6Putative cullin; Belongs to the cullin family. (863 aa)
A0A3Q0KPX8Meiotic checkpoint regulator cut4, putative. (2814 aa)
A0A3Q0KQ30Putative anaphase-promoting complex subunit; Belongs to the cullin family. (890 aa)
A0A3Q0KQH2Putative pold3 protein. (443 aa)
A0A3Q0KR94DNA primase; Belongs to the eukaryotic-type primase small subunit family. (448 aa)
A0A3Q0KS76Ris2 protein, putative. (577 aa)
A0A3Q0KT28DNA helicase; Belongs to the MCM family. (898 aa)
A0A3Q0KT7326S protease regulatory subunit, putative; Belongs to the AAA ATPase family. (433 aa)
A0A3Q0KTJ7Serine/threonine kinase. (526 aa)
A0A3Q0KTX5Ubiquitin-conjugating enzyme e2S, putative; Belongs to the ubiquitin-conjugating enzyme family. (219 aa)
A0A3Q0KUC0Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (569 aa)
A0A3Q0KUF6Putative dna replication helicase dna2. (1489 aa)
A0A3Q0KUH5DNA replication licensing factor MCM8, putative; Belongs to the MCM family. (1088 aa)
A0A3Q0KV11TATA-binding protein-associated phosphoprotein,putative. (229 aa)
A0A3Q0KVA6Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (248 aa)
A0A3Q0KVK3Histone H2A; Belongs to the histone H2A family. (131 aa)
A0A3Q0KVK7DNA polymerase. (2582 aa)
A0A5K4E9T2S-adenosylmethionine-dependent methyltransferase related. (349 aa)
A0A5K4E9Z6S-adenosylmethionine-dependent methyltransferase related. (352 aa)
A0A5K4EAG2Putative 26s protease regulatory subunit S10b. (84 aa)
A0A5K4EAI9Putative 26s protease regulatory subunit S10b. (288 aa)
A0A5K4EC46DNA replication licensing factor MCM7. (746 aa)
A0A5K4ECP8DNA helicase. (802 aa)
A0A5K4EDH5Putative ubiquitin (Ribosomal protein L40). (160 aa)
A0A5K4EDX8Putative ubiquitin (Ribosomal protein L40). (533 aa)
A0A5K4EKF4DNA polymerase epsilon subunit 2. (622 aa)
A0A5K4EKM7Uncharacterized protein. (1396 aa)
A0A5K4EKN5Replication protein A subunit. (555 aa)
A0A5K4EL72DNA polymerase epsilon subunit 2. (626 aa)
A0A5K4ELI1Uncharacterized protein. (300 aa)
A0A5K4ELP7Uncharacterized protein. (1378 aa)
A0A5K4ENB7Uncharacterized protein. (936 aa)
A0A5K4ERM7Uncharacterized protein. (958 aa)
A0A5K4ESG5Meiotic checkpoint regulator cut4, putative. (2816 aa)
A0A5K4EYZ8DNA polymerase. (2282 aa)
A0A5K4EZH3Uncharacterized protein. (476 aa)
A0A5K4EZW4DNA polymerase. (336 aa)
A0A5K4F079Uncharacterized protein. (264 aa)
A0A5K4F0I6Uncharacterized protein. (1012 aa)
A0A5K4F0M9Uncharacterized protein. (263 aa)
A0A5K4F0P7Uncharacterized protein. (232 aa)
A0A5K4F145Uncharacterized protein. (421 aa)
A0A5K4F1C0Uncharacterized protein. (888 aa)
A0A5K4F230Uncharacterized protein. (136 aa)
A0A5K4F2D0DNA polymerase. (1644 aa)
A0A5K4F2T7Uncharacterized protein. (881 aa)
A0A5K4F300Uncharacterized protein. (912 aa)
A0A5K4F814Uncharacterized protein. (333 aa)
A0A5K4F861Uncharacterized protein. (885 aa)
A0A5K4F8X3Putative cell division cycle. (643 aa)
A0A5K4F9B0Uncharacterized protein. (621 aa)
A0A5K4F9I1Uncharacterized protein. (228 aa)
A0A5K4F9K2Uncharacterized protein. (388 aa)
A0A5K4FB35Putative cell division cycle. (484 aa)
A0A5K4FBL9Uncharacterized protein. (82 aa)
A0A5K4FCG6Uncharacterized protein. (185 aa)
A0A5K4FCI3Uncharacterized protein. (1240 aa)
A0A5K4FGR5Uncharacterized protein. (219 aa)
RPT426S proteasome subunit ATPase 4; Belongs to the AAA ATPase family. (407 aa)
PA28-gammaProteasome activator PA28-gamma. (250 aa)
Smp_108390Histone H2B; Belongs to the histone H2B family. (122 aa)
Smp_053300Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
Smp_079050.1DNA primase large subunit, putative. (515 aa)
Smp_089430Ubiquitin (Ribosomal protein L40), putative. (128 aa)
Smp_178810PCI domain-containing protein. (388 aa)
Smp_182600Uncharacterized protein. (74 aa)
Smp_121430.2Proteasome subunit beta. (205 aa)
Smp_085310.126S proteasome regulatory subunit S3, putative. (396 aa)
Smp_028430Anaphase promoting complex subunit 11 homolog. (102 aa)
Smp_02663026S proteasome non-ATPase regulatory subunit 7 (M67 family). (360 aa)
Smp_058650Proteasome regulatory subunit-related. (445 aa)
c8190_g2_i1Uncharacterized protein. (92 aa)
Smp_096360Replication factor C / DNA polymerase III gamma-tau subunit, putative. (362 aa)
Smp_056500Proteasome subunit beta; Belongs to the peptidase T1B family. (247 aa)
Smp_076230Proteasome subunit alpha type. (264 aa)
Smp_042270.226S protease regulatory subunit 6a, putative; Belongs to the AAA ATPase family. (428 aa)
Smp_070930Proteasome subunit alpha type. (247 aa)
Smp_04774026S proteasome non-ATPase regulatory subunit,putative. (265 aa)
Smp_036220Histone H2B; Belongs to the histone H2B family. (122 aa)
Smp_076660Putative DNA polymerase delta small subunit. (537 aa)
Smp_079560Putative DNA replication licensing factor MCM2. (503 aa)
Smp_034490Proteasome catalytic subunit 1 (T01 family); Proteasome subunit beta type. (225 aa)
Smp_012470Putative 26s protease regulatory subunit; Belongs to the AAA ATPase family. (433 aa)
Smp_072340Putative 26s protease regulatory subunit 6b; Belongs to the AAA ATPase family. (415 aa)
Smp_025800Proteasome subunit beta. (212 aa)
Smp_047610Cell division control protein 45-related. (566 aa)
Smp_143490DNA helicase; Belongs to the MCM family. (750 aa)
Smp_007000Putative partner of sld5. (212 aa)
Smp_052390Putative origin recognition complex subunit. (485 aa)
Smp_052870Putative 26s proteasome non-ATPase regulatory subunit. (391 aa)
Smp_052910Skp1-related; Belongs to the SKP1 family. (163 aa)
Smp_066340.1Putative proteasome inhibitor. (316 aa)
Smp_151480Uncharacterized protein. (490 aa)
Smp_038080.1Putative importin beta-1. (926 aa)
Smp_052460Putative cullin; Belongs to the cullin family. (126 aa)
Smp_092280Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (254 aa)
Smp_050820Putative replication factor C / DNA polymerase III gamma-tau subunit. (357 aa)
Smp_042210Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (488 aa)
Smp_064320.126S proteasome subunit P28-related. (240 aa)
Smp_051010Putative ubiquitin-conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
Smp_077790Putative histone H2B; Belongs to the histone H2B family. (82 aa)
Smp_073410Proteasome subunit beta. (281 aa)
Smp_017070Putative 26s protease regulatory subunit S10b; Belongs to the AAA ATPase family. (395 aa)
SmPOHPad1 homolog. (313 aa)
PSMD4_SCHMA26S proteasome non-ATPase regulatory subunit 4; Binds and presumably selects ubiquitin-conjugates for destruction; Belongs to the proteasome subunit S5A family. (420 aa)
Smp_017280Ubiquitin and ribosomal protein S27-like protein. (153 aa)
Your Current Organism:
Schistosoma mansoni
NCBI taxonomy Id: 6183
Other names: S. mansoni
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