11 items (Schistosoma mansoni) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Smp_082430	Putative uridine phosphorylase. (296 aa)
	A0A3Q0KU65	Purine nucleoside phosphorylase. (214 aa)
	A0A5K4EWY8	Purine nucleoside phosphorylase. (67 aa)
	A0A5K4EWZ0	Purine nucleoside phosphorylase. (320 aa)
	A0A5K4EY01	S-methyl-5'-thioadenosine phosphorylase. (295 aa)
	A0A5K4EY11	Purine nucleoside phosphorylase. (260 aa)
	A0A5K4F6A1	Putative uridine phosphorylase. (286 aa)
	A0A5K4F3L4	Uncharacterized protein. (279 aa)
	A0A5K4F407	Purine nucleoside phosphorylase. (287 aa)
	Smp_171620	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (299 aa)
	I0B503_SCHMA	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (299 aa)

Your Current Organism:

Schistosoma mansoni

NCBI taxonomy Id: 6183
Other names: S. mansoni

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A3Q0KU65	A0A5K4F6A1	A0A3Q0KU65	A0A5K4F6A1	Purine nucleoside phosphorylase.	Putative uridine phosphorylase.	0.556
A0A3Q0KU65	I0B503_SCHMA	A0A3Q0KU65	I0B503	Purine nucleoside phosphorylase.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.439
A0A3Q0KU65	Smp_082430	A0A3Q0KU65	G4VGI0	Purine nucleoside phosphorylase.	Putative uridine phosphorylase.	0.553
A0A3Q0KU65	Smp_171620	A0A3Q0KU65	G4VP86	Purine nucleoside phosphorylase.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.440
A0A5K4EWY8	A0A5K4F6A1	A0A5K4EWY8	A0A5K4F6A1	Purine nucleoside phosphorylase.	Putative uridine phosphorylase.	0.556
A0A5K4EWY8	I0B503_SCHMA	A0A5K4EWY8	I0B503	Purine nucleoside phosphorylase.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.439
A0A5K4EWY8	Smp_082430	A0A5K4EWY8	G4VGI0	Purine nucleoside phosphorylase.	Putative uridine phosphorylase.	0.553
A0A5K4EWY8	Smp_171620	A0A5K4EWY8	G4VP86	Purine nucleoside phosphorylase.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.440
A0A5K4EWZ0	A0A5K4F407	A0A5K4EWZ0	A0A5K4F407	Purine nucleoside phosphorylase.	Purine nucleoside phosphorylase.	0.901
A0A5K4EWZ0	A0A5K4F6A1	A0A5K4EWZ0	A0A5K4F6A1	Purine nucleoside phosphorylase.	Putative uridine phosphorylase.	0.963
A0A5K4EWZ0	Smp_082430	A0A5K4EWZ0	G4VGI0	Purine nucleoside phosphorylase.	Putative uridine phosphorylase.	0.972
A0A5K4EY01	A0A5K4F6A1	A0A5K4EY01	A0A5K4F6A1	S-methyl-5'-thioadenosine phosphorylase.	Putative uridine phosphorylase.	0.533
A0A5K4EY01	Smp_082430	A0A5K4EY01	G4VGI0	S-methyl-5'-thioadenosine phosphorylase.	Putative uridine phosphorylase.	0.533
A0A5K4EY11	A0A5K4F6A1	A0A5K4EY11	A0A5K4F6A1	Purine nucleoside phosphorylase.	Putative uridine phosphorylase.	0.556
A0A5K4EY11	I0B503_SCHMA	A0A5K4EY11	I0B503	Purine nucleoside phosphorylase.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.439
A0A5K4EY11	Smp_082430	A0A5K4EY11	G4VGI0	Purine nucleoside phosphorylase.	Putative uridine phosphorylase.	0.553
A0A5K4EY11	Smp_171620	A0A5K4EY11	G4VP86	Purine nucleoside phosphorylase.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.440
A0A5K4F3L4	A0A5K4F6A1	A0A5K4F3L4	A0A5K4F6A1	Uncharacterized protein.	Putative uridine phosphorylase.	0.503
A0A5K4F3L4	Smp_082430	A0A5K4F3L4	G4VGI0	Uncharacterized protein.	Putative uridine phosphorylase.	0.503
A0A5K4F407	A0A5K4EWZ0	A0A5K4F407	A0A5K4EWZ0	Purine nucleoside phosphorylase.	Purine nucleoside phosphorylase.	0.901