45 items (Schistosoma mansoni) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A3Q0KB95	Filamin. (2483 aa)
	DLC	Dynein light chain; Acts as a non-catalytic accessory component of a dynein complex; Belongs to the dynein light chain family. (89 aa)
	DYL2_SCHMA	Probable dynein light chain; Acts as a non-catalytic accessory component of a dynein complex; Belongs to the dynein light chain family. (89 aa)
	CALR_SCHMA	Calreticulin; Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity). (393 aa)
	Smp_043150	Putative smirv1 protein; Putative smirv1 protein; SmIrV1 protein; SmIrV1 protein. (582 aa)
	Smp_142300	Putative polypyrimidine tract binding protein. (584 aa)
	Smp_086590	Putative actin-depolymerizing factor; Belongs to the actin-binding proteins ADF family. (140 aa)
	Smp_040680	Dynein light chain. (90 aa)
	Smp_095500	Dynein light chain. (90 aa)
	Smp_174510	Dynein light chain. (104 aa)
	Smp_095480	Dynein light chain. (92 aa)
	Smp_195080	Cofilin; Belongs to the actin-binding proteins ADF family. (140 aa)
	Smp_125020	Dynein light chain. (89 aa)
	Smp_051400	Dynein light chain. (89 aa)
	Smp_120700.1	Cofilin, actophorin, putative; Belongs to the actin-binding proteins ADF family. (135 aa)
	Smp_187140	Subfamily C1A non-peptidase homologue (C01 family); Belongs to the peptidase C1 family. (342 aa)
	Smp_019310	Dynein light chain. (103 aa)
	A0A5K4FDB3	Uncharacterized protein. (90 aa)
	A0A5K4FAR3	Dynein light chain. (92 aa)
	A0A5K4F6N5	Filamin-related. (2722 aa)
	A0A5K4F5C0	Splicing factor Prp8, putative. (2306 aa)
	A0A5K4F492	Filamin-related. (2325 aa)
	A0A5K4F407	Purine nucleoside phosphorylase. (287 aa)
	A0A5K4F2Q5	Uncharacterized protein. (432 aa)
	A0A5K4EY11	Purine nucleoside phosphorylase. (260 aa)
	A0A5K4EWZ0	Purine nucleoside phosphorylase. (320 aa)
	A0A5K4EWY8	Purine nucleoside phosphorylase. (67 aa)
	A0A5K4E8T7	Filamin. (2617 aa)
	A0A5K4E873	Filamin. (2611 aa)
	A0A5K4E821	Filamin. (2577 aa)
	A0A5K4E7M6	Filamin. (1596 aa)
	A0A3Q0KU65	Purine nucleoside phosphorylase. (214 aa)
	A0A3Q0KTP8	Dynein light chain. (89 aa)
	A0A3Q0KNV9	Spectrin beta chain; Belongs to the spectrin family. (2038 aa)
	A0A3Q0KMW9	Polypyrimidine tract binding protein, putative. (603 aa)
	A0A3Q0KLC4	Putative spectrin beta chain. (2662 aa)
	A0A3Q0KJZ9	WD-repeat protein, putative. (382 aa)
	A0A3Q0KJA1	DNA helicase; Belongs to the MCM family. (806 aa)
	A0A3Q0KFF1	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (238 aa)
	A0A3Q0KFE4	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	A0A3Q0KEH4	Putative polypyrimidine tract binding protein. (620 aa)
	A0A3Q0KEH2	Putative adenosine deaminase. (348 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (771 aa)
	A0A3Q0KDW8	Calreticulin. (393 aa)
	A0A3Q0KBV3	Dynein light chain. (83 aa)

Your Current Organism:

Schistosoma mansoni

NCBI taxonomy Id: 6183
Other names: S. mansoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A3Q0KDW8	Smp_043150	A0A3Q0KDW8	Q04702	Calreticulin.	Putative smirv1 protein; Putative smirv1 protein; SmIrV1 protein; SmIrV1 protein.	0.952
A0A3Q0KEH2	A0A3Q0KU65	A0A3Q0KEH2	A0A3Q0KU65	Putative adenosine deaminase.	Purine nucleoside phosphorylase.	0.691
A0A3Q0KEH2	A0A5K4EWY8	A0A3Q0KEH2	A0A5K4EWY8	Putative adenosine deaminase.	Purine nucleoside phosphorylase.	0.691
A0A3Q0KEH2	A0A5K4EWZ0	A0A3Q0KEH2	A0A5K4EWZ0	Putative adenosine deaminase.	Purine nucleoside phosphorylase.	0.975
A0A3Q0KEH2	A0A5K4EY11	A0A3Q0KEH2	A0A5K4EY11	Putative adenosine deaminase.	Purine nucleoside phosphorylase.	0.691
A0A3Q0KEH2	A0A5K4F407	A0A3Q0KEH2	A0A5K4F407	Putative adenosine deaminase.	Purine nucleoside phosphorylase.	0.975
A0A3Q0KEH4	A0A3Q0KJZ9	A0A3Q0KEH4	A0A3Q0KJZ9	Putative polypyrimidine tract binding protein.	WD-repeat protein, putative.	0.521
A0A3Q0KEH4	A0A5K4F2Q5	A0A3Q0KEH4	A0A5K4F2Q5	Putative polypyrimidine tract binding protein.	Uncharacterized protein.	0.520
A0A3Q0KEH4	A0A5K4F5C0	A0A3Q0KEH4	A0A5K4F5C0	Putative polypyrimidine tract binding protein.	Splicing factor Prp8, putative.	0.599
A0A3Q0KFE4	A0A3Q0KJA1	A0A3Q0KFE4	A0A3Q0KJA1	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA helicase; Belongs to the MCM family.	0.802
A0A3Q0KFE4	MCM7	A0A3Q0KFE4	A0A3Q0KE52	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.824
A0A3Q0KFF1	A0A3Q0KJA1	A0A3Q0KFF1	A0A3Q0KJA1	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA helicase; Belongs to the MCM family.	0.802
A0A3Q0KFF1	MCM7	A0A3Q0KFF1	A0A3Q0KE52	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.824
A0A3Q0KJA1	A0A3Q0KFE4	A0A3Q0KJA1	A0A3Q0KFE4	DNA helicase; Belongs to the MCM family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.802
A0A3Q0KJA1	A0A3Q0KFF1	A0A3Q0KJA1	A0A3Q0KFF1	DNA helicase; Belongs to the MCM family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.802
A0A3Q0KJA1	MCM7	A0A3Q0KJA1	A0A3Q0KE52	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.998
A0A3Q0KJZ9	A0A3Q0KEH4	A0A3Q0KJZ9	A0A3Q0KEH4	WD-repeat protein, putative.	Putative polypyrimidine tract binding protein.	0.521
A0A3Q0KJZ9	A0A3Q0KMW9	A0A3Q0KJZ9	A0A3Q0KMW9	WD-repeat protein, putative.	Polypyrimidine tract binding protein, putative.	0.521
A0A3Q0KJZ9	A0A5K4F2Q5	A0A3Q0KJZ9	A0A5K4F2Q5	WD-repeat protein, putative.	Uncharacterized protein.	0.576
A0A3Q0KJZ9	A0A5K4F5C0	A0A3Q0KJZ9	A0A5K4F5C0	WD-repeat protein, putative.	Splicing factor Prp8, putative.	0.993