51 items (Schistosoma mansoni) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A3Q0KC34	Putative adenosine kinase. (341 aa)
	A0A3Q0KC36	Putative adenosine kinase. (341 aa)
	A0A3Q0KEH2	Putative adenosine deaminase. (348 aa)
	A0A3Q0KFS8	Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. Belongs to the adenylate kinase family. AK6 subfamily. (174 aa)
	A0A3Q0KGQ7	Putative adenylate kinase 1; Belongs to the adenylate kinase family. (239 aa)
	A0A3Q0KGU1	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (189 aa)
	A0A3Q0KH21	Pyruvate kinase; Belongs to the pyruvate kinase family. (561 aa)
	A0A3Q0KID3	Adenosine diphosphatase, putative; Belongs to the GDA1/CD39 NTPase family. (563 aa)
	A0A3Q0KIP8	Putative phosphoglucomutase; Belongs to the phosphohexose mutase family. (600 aa)
	A0A3Q0KJ78	Nucleoside diphosphate kinase; Belongs to the NDK family. (143 aa)
	A0A3Q0KJK7	Soluble guanylyl cyclase beta-3, putative. (934 aa)
	A0A3Q0KJQ9	Adenylate cyclase type IX, putative; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (643 aa)
	A0A3Q0KKX9	Guanylate cyclase. (1254 aa)
	A0A3Q0KNG7	Phosphodiesterase. (1022 aa)
	A0A3Q0KPJ1	Hypoxanthine-guanine phosphoribosyltransferase,putative. (227 aa)
	A0A3Q0KRR6	Uncharacterized protein. (798 aa)
	A0A3Q0KUB8	Putative 2,3-cyclic-nucleotide 2-phosphodiesterase; Belongs to the 5'-nucleotidase family. (574 aa)
	A0A5K4EJM6	5'-nucleotidase. (332 aa)
	A0A5K4EMT8	Phosphodiesterase. (170 aa)
	A0A5K4ETS2	Nucleoside diphosphate kinase. (369 aa)
	A0A5K4EWZ0	Purine nucleoside phosphorylase. (320 aa)
	A0A5K4EZS1	Uncharacterized protein. (381 aa)
	A0A5K4EZZ9	Uncharacterized protein. (550 aa)
	A0A5K4F206	Uncharacterized protein. (650 aa)
	A0A5K4F243	Uncharacterized protein. (532 aa)
	A0A5K4F2X8	Putative high-affinity cgmp-specific 3,5-cyclic phosphodiesterase. (640 aa)
	A0A5K4F3M5	Uncharacterized protein. (994 aa)
	A0A5K4F407	Purine nucleoside phosphorylase. (287 aa)
	A0A5K4F5F9	Uncharacterized protein. (608 aa)
	A0A5K4F8A3	Uncharacterized protein. (226 aa)
	A0A5K4FA18	Uncharacterized protein. (805 aa)
	A0A5K4FBW1	Uncharacterized protein. (249 aa)
	Smp_055890	Ribonucleoside-diphosphate reductase small chain, putative. (365 aa)
	Smp_055990	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Belongs to the adenylosuccinate synthetase family. (426 aa)
	Smp_197230	Adenylate kinase, putative; Belongs to the adenylate kinase family. (395 aa)
	Smp_168500	Hypoxanthine-guanine phosphoribosyltransferase,putative. (228 aa)
	Smp_081790	Nucleoside diphosphate kinase; Belongs to the NDK family. (149 aa)
	Smp_151190	Retinal rod rhodopsin-sensitive cgmp 3',5'-cyclic phosphodiesterase, putative. (151 aa)
	Smp_153160	Adenylate kinase 3, putative; Belongs to the adenylate kinase family. (230 aa)
	Smp_063830	GMP synthetase (Glutamine-hydrolysing). (739 aa)
	Smp_012930	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (509 aa)
	Smp_071390	Adenylate kinase; Putative adenylate kinase; Belongs to the adenylate kinase family. (197 aa)
	Smp_022090	Putative ribose-phosphate pyrophosphokinase 1. (318 aa)
	Smp_009030	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (837 aa)
	Smp_154270	Putative adenylsulfate kinase. (613 aa)
	Smp_151260	Putative adenine phosphoribosyltransferase. (142 aa)
	Smp_054410	Putative adenine phosphoribosyltransferase. (196 aa)
	Smp_054360	Putative adenine phosphoribosyltransferase. (186 aa)
	Smp_038030	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (480 aa)
	HGPRT	Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). (284 aa)
	ATPDase1	Putative atp-diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (544 aa)

Your Current Organism:

Schistosoma mansoni

NCBI taxonomy Id: 6183
Other names: S. mansoni

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A3Q0KC34	A0A3Q0KC36	A0A3Q0KC34	A0A3Q0KC36	Putative adenosine kinase.	Putative adenosine kinase.	0.903
A0A3Q0KC34	A0A3Q0KEH2	A0A3Q0KC34	A0A3Q0KEH2	Putative adenosine kinase.	Putative adenosine deaminase.	0.986
A0A3Q0KC34	A0A3Q0KFS8	A0A3Q0KC34	A0A3Q0KFS8	Putative adenosine kinase.	Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. Belongs to the adenylate kinase family. AK6 subfamily.	0.909
A0A3Q0KC34	A0A3Q0KGQ7	A0A3Q0KC34	A0A3Q0KGQ7	Putative adenosine kinase.	Putative adenylate kinase 1; Belongs to the adenylate kinase family.	0.969
A0A3Q0KC34	A0A3Q0KH21	A0A3Q0KC34	A0A3Q0KH21	Putative adenosine kinase.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.462
A0A3Q0KC34	A0A3Q0KIP8	A0A3Q0KC34	A0A3Q0KIP8	Putative adenosine kinase.	Putative phosphoglucomutase; Belongs to the phosphohexose mutase family.	0.546
A0A3Q0KC34	A0A3Q0KNG7	A0A3Q0KC34	A0A3Q0KNG7	Putative adenosine kinase.	Phosphodiesterase.	0.910
A0A3Q0KC34	A0A3Q0KRR6	A0A3Q0KC34	A0A3Q0KRR6	Putative adenosine kinase.	Uncharacterized protein.	0.936
A0A3Q0KC34	A0A3Q0KUB8	A0A3Q0KC34	A0A3Q0KUB8	Putative adenosine kinase.	Putative 2,3-cyclic-nucleotide 2-phosphodiesterase; Belongs to the 5'-nucleotidase family.	0.944
A0A3Q0KC34	A0A5K4EJM6	A0A3Q0KC34	A0A5K4EJM6	Putative adenosine kinase.	5'-nucleotidase.	0.903
A0A3Q0KC34	A0A5K4EMT8	A0A3Q0KC34	A0A5K4EMT8	Putative adenosine kinase.	Phosphodiesterase.	0.910
A0A3Q0KC34	A0A5K4EWZ0	A0A3Q0KC34	A0A5K4EWZ0	Putative adenosine kinase.	Purine nucleoside phosphorylase.	0.963
A0A3Q0KC34	A0A5K4EZZ9	A0A3Q0KC34	A0A5K4EZZ9	Putative adenosine kinase.	Uncharacterized protein.	0.462
A0A3Q0KC34	A0A5K4F206	A0A3Q0KC34	A0A5K4F206	Putative adenosine kinase.	Uncharacterized protein.	0.907
A0A3Q0KC34	A0A5K4F3M5	A0A3Q0KC34	A0A5K4F3M5	Putative adenosine kinase.	Uncharacterized protein.	0.976
A0A3Q0KC34	A0A5K4F407	A0A3Q0KC34	A0A5K4F407	Putative adenosine kinase.	Purine nucleoside phosphorylase.	0.963
A0A3Q0KC34	A0A5K4F5F9	A0A3Q0KC34	A0A5K4F5F9	Putative adenosine kinase.	Uncharacterized protein.	0.916
A0A3Q0KC34	A0A5K4FBW1	A0A3Q0KC34	A0A5K4FBW1	Putative adenosine kinase.	Uncharacterized protein.	0.903
A0A3Q0KC34	ATPDase1	A0A3Q0KC34	Q7YTA4	Putative adenosine kinase.	Putative atp-diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family.	0.909
A0A3Q0KC34	Smp_012930	A0A3Q0KC34	G4V9I5	Putative adenosine kinase.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.479