(53 nodes) Mixed, incl. Transmembrane receptor protein serine/threonine kinase signaling pathway, and Hippo signaling network (Schistosoma haematobium)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MS3_10031	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (637 aa)
	MS3_11274	Uncharacterized protein. (251 aa)
	MS3_00366	Uncharacterized protein. (427 aa)
	MS3_00221	Protein scalloped. (248 aa)
	MS3_00960	Mothers against decapentaplegic homolog. (654 aa)
	MS3_01247	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (677 aa)
	MS3_00346	Uncharacterized protein. (200 aa)
	MS3_00374	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1039 aa)
	MS3_01490	NEDD4-like E3 ubiquitin-protein ligase WWP1. (239 aa)
	MS3_01768	Uncharacterized protein. (272 aa)
	MS3_02873	RING-type domain-containing protein. (839 aa)
	MS3_03093	Arrestin_N domain-containing protein. (804 aa)
	MS3_01500	E3 ubiquitin-protein ligase Itchy. (72 aa)
	MS3_01770	Tensin-1. (401 aa)
	MS3_02468	Uncharacterized protein. (461 aa)
	MS3_02713	TBC1 domain family member 30. (1070 aa)
	MS3_03118	Dual specificity protein phosphatase 15. (515 aa)
	MS3_04564	Growth hormone-regulated TBC protein 1-A. (285 aa)
	MS3_04594	Mothers against decapentaplegic homolog. (901 aa)
	MS3_05523	Dual specificity protein phosphatase CDC14A. (189 aa)
	MS3_06407	Putative ubiquitin carboxyl-terminal hydrolase FAF-X; Belongs to the peptidase C19 family. (3574 aa)
	MS3_05434	MOB kinase activator 1B. (239 aa)
	MS3_06718	Scaffold protein salvador. (1366 aa)
	MS3_06831	Uncharacterized protein. (37 aa)
	MS3_05737	Uncharacterized protein. (575 aa)
	MS3_06593	Serine/threonine-protein kinase LATS1. (1163 aa)
	MS3_06797	Serine/threonine-protein kinase 3. (628 aa)
	MS3_08095	Protein DDI1 2. (398 aa)
	MS3_09529	WW domain-containing protein. (325 aa)
	MS3_08837	MOB kinase activator 2. (329 aa)
	MS3_10988	Uncharacterized protein. (219 aa)
	MS3_10165	Mothers against decapentaplegic homolog. (699 aa)
	MS3_03495	Transcriptional enhancer factor TEF-3. (406 aa)
	MS3_07548	Small G protein signaling modulator 3-like protein. (567 aa)
	MS3_10532	TBC1 domain family member 30. (269 aa)
	MS3_11210	Zinc finger FYVE domain-containing protein 16. (311 aa)
	MS3_11453	TGF_BETA_2 domain-containing protein. (54 aa)
	MS3_00225	Transcriptional enhancer factor TEF-1. (846 aa)
	MS3_01030	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (643 aa)
	MS3_01479	Mothers against decapentaplegic 5. (273 aa)
	MS3_01495	NEDD4-like E3 ubiquitin-protein ligase WWP2. (109 aa)
	MS3_01763	Uncharacterized protein. (731 aa)
	MS3_02022	TBC1 domain family member 2B. (1199 aa)
	MS3_02059	Ski oncogene. (1389 aa)
	MS3_04078	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (652 aa)
	MS3_05590	Protein DVR-1. (745 aa)
	MS3_06363	Mothers against decapentaplegic 1. (330 aa)
	MS3_06729	Dual specificity protein phosphatase 23. (150 aa)
	MS3_06827	Uncharacterized protein. (151 aa)
	MS3_07153	Dual specificity protein phosphatase 10. (523 aa)
	MS3_09654	E3 ubiquitin-protein ligase NEDD4-like. (424 aa)
	MS3_09767	Uncharacterized protein. (273 aa)
	MS3_09852	DUF3480 domain-containing protein. (643 aa)

Your Current Organism:

Schistosoma haematobium

NCBI taxonomy Id: 6185
Other names: S. haematobium

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MS3_00221	MS3_00346	A0A094ZEB2	A0A094ZHC0	Protein scalloped.	Uncharacterized protein.	0.814
MS3_00221	MS3_00366	A0A094ZEB2	A0A094ZD93	Protein scalloped.	Uncharacterized protein.	0.814
MS3_00221	MS3_01490	A0A094ZEB2	A0A094ZHI0	Protein scalloped.	NEDD4-like E3 ubiquitin-protein ligase WWP1.	0.533
MS3_00221	MS3_01495	A0A094ZEB2	A0A095BWE7	Protein scalloped.	NEDD4-like E3 ubiquitin-protein ligase WWP2.	0.533
MS3_00221	MS3_01500	A0A094ZEB2	A0A094ZKD6	Protein scalloped.	E3 ubiquitin-protein ligase Itchy.	0.533
MS3_00221	MS3_09529	A0A094ZEB2	A0A095A2F8	Protein scalloped.	WW domain-containing protein.	0.533
MS3_00221	MS3_09654	A0A094ZEB2	A0A095CEE9	Protein scalloped.	E3 ubiquitin-protein ligase NEDD4-like.	0.533
MS3_00225	MS3_00346	A0A095BTE6	A0A094ZHC0	Transcriptional enhancer factor TEF-1.	Uncharacterized protein.	0.814
MS3_00225	MS3_00366	A0A095BTE6	A0A094ZD93	Transcriptional enhancer factor TEF-1.	Uncharacterized protein.	0.814
MS3_00225	MS3_01490	A0A095BTE6	A0A094ZHI0	Transcriptional enhancer factor TEF-1.	NEDD4-like E3 ubiquitin-protein ligase WWP1.	0.533
MS3_00225	MS3_01495	A0A095BTE6	A0A095BWE7	Transcriptional enhancer factor TEF-1.	NEDD4-like E3 ubiquitin-protein ligase WWP2.	0.533
MS3_00225	MS3_01500	A0A095BTE6	A0A094ZKD6	Transcriptional enhancer factor TEF-1.	E3 ubiquitin-protein ligase Itchy.	0.533
MS3_00225	MS3_09529	A0A095BTE6	A0A095A2F8	Transcriptional enhancer factor TEF-1.	WW domain-containing protein.	0.533
MS3_00225	MS3_09654	A0A095BTE6	A0A095CEE9	Transcriptional enhancer factor TEF-1.	E3 ubiquitin-protein ligase NEDD4-like.	0.533
MS3_00346	MS3_00221	A0A094ZHC0	A0A094ZEB2	Uncharacterized protein.	Protein scalloped.	0.814
MS3_00346	MS3_00225	A0A094ZHC0	A0A095BTE6	Uncharacterized protein.	Transcriptional enhancer factor TEF-1.	0.814
MS3_00346	MS3_00960	A0A094ZHC0	A0A094ZEM0	Uncharacterized protein.	Mothers against decapentaplegic homolog.	0.579
MS3_00346	MS3_01030	A0A094ZHC0	A0A095BVA8	Uncharacterized protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.420
MS3_00346	MS3_01247	A0A094ZHC0	A0A094ZF70	Uncharacterized protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.426
MS3_00346	MS3_01479	A0A094ZHC0	A0A095BWC9	Uncharacterized protein.	Mothers against decapentaplegic 5.	0.464