STRINGSTRING
MS3_03062 MS3_03062 MS3_02843 MS3_02843 MS3_01509 MS3_01509 MS3_06719 MS3_06719 MS3_03022 MS3_03022 MS3_05532 MS3_05532 MS3_00187 MS3_00187 MS3_02908 MS3_02908 FEN1 FEN1 MS3_07592 MS3_07592 MS3_07763 MS3_07763 MS3_08432 MS3_08432 MS3_08370 MS3_08370 MS3_07105 MS3_07105 MS3_09994 MS3_09994 MS3_08338 MS3_08338 MS3_10803 MS3_10803 MS3_09516 MS3_09516 MS3_10892 MS3_10892 MS3_00415 MS3_00415 MS3_00555 MS3_00555 MS3_00801 MS3_00801 MS3_05283 MS3_05283 MS3_05685 MS3_05685 MS3_06854 MS3_06854 MS3_08937 MS3_08937 MS3_09408 MS3_09408 MS3_03358 MS3_03358 MS3_03679 MS3_03679 MS3_04148 MS3_04148 MS3_06841 MS3_06841 MS3_07839 MS3_07839 MS3_00046 MS3_00046
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MS3_03062Pyruvate kinase; Belongs to the pyruvate kinase family. (271 aa)
MS3_02843Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1265 aa)
MS3_01509S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (351 aa)
MS3_06719Phosphoglucomutase-2; Belongs to the phosphohexose mutase family. (518 aa)
MS3_03022Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (711 aa)
MS3_05532Protein phosphatase 1B. (378 aa)
MS3_00187Guanine nucleotide-binding protein G(O) subunit alpha. (355 aa)
MS3_02908Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (582 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (390 aa)
MS3_07592Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (695 aa)
MS3_07763Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (416 aa)
MS3_08432Protein phosphatase 1A. (407 aa)
MS3_083705-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (203 aa)
MS3_07105Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (351 aa)
MS3_09994Phosphoglucomutase-1; Belongs to the phosphohexose mutase family. (575 aa)
MS3_08338Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (597 aa)
MS3_10803Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (636 aa)
MS3_09516Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (557 aa)
MS3_10892PPM-type phosphatase domain-containing protein. (377 aa)
MS3_00415DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (297 aa)
MS3_00555Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (589 aa)
MS3_00801Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (776 aa)
MS3_05283Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (405 aa)
MS3_05685Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (611 aa)
MS3_06854Guanine nucleotide-binding protein G(I) subunit alpha. (369 aa)
MS3_08937Pyruvate kinase; Belongs to the pyruvate kinase family. (564 aa)
MS3_094085'-nucleotidase domain-containing protein 3. (471 aa)
MS3_03358Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (365 aa)
MS3_03679Integrin-linked kinase-associated serine/threonine phosphatase 2C. (774 aa)
MS3_04148DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (491 aa)
MS3_06841Protein phosphatase; Belongs to the PP2C family. (380 aa)
MS3_07839Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (191 aa)
MS3_00046Guanine nucleotide-binding protein G(I) subunit alpha. (273 aa)
Your Current Organism:
Schistosoma haematobium
NCBI taxonomy Id: 6185
Other names: S. haematobium
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