32 items (Schistosoma haematobium) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	MS3_00804	Glutamate [NMDA] receptor subunit 1. (1129 aa)
	MS3_11568	Ncstrn_small domain-containing protein. (135 aa)
	MS3_00621	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (392 aa)
	MS3_02844	Serine/threonine-protein kinase PAK 3. (1134 aa)
	MS3_03658	Ephrin type-B receptor 1. (1006 aa)
	MS3_04629	Ephrin type-A receptor 3. (767 aa)
	MS3_04907	Actin-related protein 3; Belongs to the actin family. (326 aa)
	MS3_05062	Serine/threonine-protein kinase PAK 2. (111 aa)
	MS3_04303	Serine/threonine-protein kinase PAK 3. (580 aa)
	MS3_05537	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
	MS3_04627	Ephrin type-B receptor 1. (512 aa)
	MS3_06412	Serine/threonine-protein kinase PAK 3. (729 aa)
	MS3_07858	Fibronectin type III domain-containing protein 3B. (2026 aa)
	MS3_08476	Uncharacterized protein. (121 aa)
	MS3_08848	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (200 aa)
	MS3_07856	Actin-related protein 2/3 complex subunit 1A. (174 aa)
	MS3_09814	Actin-related protein 2/3 complex subunit 1A. (212 aa)
	MS3_00886	Syntenin-1. (325 aa)
	MS3_01170	Uncharacterized protein. (1066 aa)
	MS3_04306	Serine/threonine-protein kinase PAK 3. (441 aa)
	MS3_05026	Cofilin; Belongs to the actin-binding proteins ADF family. (149 aa)
	MS3_05776	Neural Wiskott-Aldrich syndrome protein. (264 aa)
	MS3_07475	Syntenin-2. (254 aa)
	MS3_07860	Fibronectin type-III domain-containing protein 3A. (671 aa)
	MS3_08797	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (403 aa)
	MS3_11096	Nicastrin. (207 aa)
	MS3_10527	Uncharacterized protein. (79 aa)
	MS3_10879	Gamma-secretase subunit Aph-1. (284 aa)
	MS3_00351	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (359 aa)
	MS3_00613	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (329 aa)
	MS3_06180	Syndecan. (479 aa)
	MS3_06863	Uncharacterized protein. (274 aa)

Your Current Organism:

Schistosoma haematobium

NCBI taxonomy Id: 6185
Other names: S. haematobium

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MS3_00351	MS3_00613	A0A095BTU9	A0A095BUC8	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.982
MS3_00351	MS3_00621	A0A095BTU9	A0A094ZFB3	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.982
MS3_00351	MS3_04907	A0A095BTU9	A0A094ZPG8	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Actin-related protein 3; Belongs to the actin family.	0.999
MS3_00351	MS3_05026	A0A095BTU9	A0A095AQX5	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Cofilin; Belongs to the actin-binding proteins ADF family.	0.817
MS3_00351	MS3_05537	A0A095BTU9	A0A094ZSN9	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.	0.999
MS3_00351	MS3_05776	A0A095BTU9	A0A095ASP5	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Neural Wiskott-Aldrich syndrome protein.	0.930
MS3_00351	MS3_07856	A0A095BTU9	A0A095A1R6	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Actin-related protein 2/3 complex subunit 1A.	0.976
MS3_00351	MS3_08848	A0A095BTU9	A0A094ZZH9	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.999
MS3_00351	MS3_09814	A0A095BTU9	A0A095A226	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Actin-related protein 2/3 complex subunit 1A.	0.976
MS3_00351	MS3_10527	A0A095BTU9	A0A095BR89	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	Uncharacterized protein.	0.930
MS3_00613	MS3_00351	A0A095BUC8	A0A095BTU9	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.982
MS3_00613	MS3_00621	A0A095BUC8	A0A094ZFB3	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.903
MS3_00613	MS3_04907	A0A095BUC8	A0A094ZPG8	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Actin-related protein 3; Belongs to the actin family.	0.987
MS3_00613	MS3_05026	A0A095BUC8	A0A095AQX5	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Cofilin; Belongs to the actin-binding proteins ADF family.	0.449
MS3_00613	MS3_05537	A0A095BUC8	A0A094ZSN9	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.	0.996
MS3_00613	MS3_05776	A0A095BUC8	A0A095ASP5	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Neural Wiskott-Aldrich syndrome protein.	0.821
MS3_00613	MS3_07856	A0A095BUC8	A0A095A1R6	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Actin-related protein 2/3 complex subunit 1A.	0.948
MS3_00613	MS3_08848	A0A095BUC8	A0A094ZZH9	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.997
MS3_00613	MS3_09814	A0A095BUC8	A0A095A226	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Actin-related protein 2/3 complex subunit 1A.	0.991
MS3_00613	MS3_10527	A0A095BUC8	A0A095BR89	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Uncharacterized protein.	0.821