(15 nodes) Alanine, aspartate and glutamate metabolism network (Schistosoma haematobium)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MS3_00663	Aspartate aminotransferase, cytoplasmic. (230 aa)
	MS3_00805	Alanine aminotransferase 2. (493 aa)
	MS3_02538	Alanine aminotransferase 2. (495 aa)
	MS3_02399	Glutaminase kidney isoform, mitochondrial. (354 aa)
	MS3_04063	Adenylosuccinate lyase. (376 aa)
	MS3_04225	Aspartate aminotransferase. (419 aa)
	MS3_07403	Glutamine synthetase. (413 aa)
	MS3_09488	CAD protein. (1292 aa)
	MS3_01289	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (481 aa)
	MS3_03986	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1. (638 aa)
	MS3_04646	Omega-amidase NIT2. (537 aa)
	MS3_05283	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (405 aa)
	MS3_09350	Succinate-semialdehyde dehydrogenase, mitochondrial; Belongs to the aldehyde dehydrogenase family. (541 aa)
	MS3_10816	Glutamate dehydrogenase, mitochondrial; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (556 aa)
	MS3_07055	D-aspartate oxidase. (332 aa)

Your Current Organism:

Schistosoma haematobium

NCBI taxonomy Id: 6185
Other names: S. haematobium

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MS3_00663	MS3_00805	A0A094ZDU3	A0A094ZFU7	Aspartate aminotransferase, cytoplasmic.	Alanine aminotransferase 2.	0.979
MS3_00663	MS3_01289	A0A094ZDU3	A0A095AGW3	Aspartate aminotransferase, cytoplasmic.	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.948
MS3_00663	MS3_02538	A0A094ZDU3	A0A094ZIG9	Aspartate aminotransferase, cytoplasmic.	Alanine aminotransferase 2.	0.979
MS3_00663	MS3_04225	A0A094ZDU3	A0A094ZS98	Aspartate aminotransferase, cytoplasmic.	Aspartate aminotransferase.	0.972
MS3_00663	MS3_04646	A0A094ZDU3	A0A095APY8	Aspartate aminotransferase, cytoplasmic.	Omega-amidase NIT2.	0.906
MS3_00663	MS3_05283	A0A094ZDU3	A0A095ARH4	Aspartate aminotransferase, cytoplasmic.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.929
MS3_00663	MS3_07055	A0A094ZDU3	A0A095C8U5	Aspartate aminotransferase, cytoplasmic.	D-aspartate oxidase.	0.933
MS3_00663	MS3_07403	A0A094ZDU3	A0A094ZXA3	Aspartate aminotransferase, cytoplasmic.	Glutamine synthetase.	0.442
MS3_00663	MS3_09350	A0A094ZDU3	A0A095B183	Aspartate aminotransferase, cytoplasmic.	Succinate-semialdehyde dehydrogenase, mitochondrial; Belongs to the aldehyde dehydrogenase family.	0.431
MS3_00663	MS3_09488	A0A094ZDU3	A0A095A149	Aspartate aminotransferase, cytoplasmic.	CAD protein.	0.909
MS3_00663	MS3_10816	A0A094ZDU3	A0A095BRR6	Aspartate aminotransferase, cytoplasmic.	Glutamate dehydrogenase, mitochondrial; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.961
MS3_00805	MS3_00663	A0A094ZFU7	A0A094ZDU3	Alanine aminotransferase 2.	Aspartate aminotransferase, cytoplasmic.	0.979
MS3_00805	MS3_02538	A0A094ZFU7	A0A094ZIG9	Alanine aminotransferase 2.	Alanine aminotransferase 2.	0.902
MS3_00805	MS3_04225	A0A094ZFU7	A0A094ZS98	Alanine aminotransferase 2.	Aspartate aminotransferase.	0.981
MS3_00805	MS3_04646	A0A094ZFU7	A0A095APY8	Alanine aminotransferase 2.	Omega-amidase NIT2.	0.715
MS3_00805	MS3_07403	A0A094ZFU7	A0A094ZXA3	Alanine aminotransferase 2.	Glutamine synthetase.	0.454
MS3_00805	MS3_09488	A0A094ZFU7	A0A095A149	Alanine aminotransferase 2.	CAD protein.	0.527
MS3_00805	MS3_10816	A0A094ZFU7	A0A095BRR6	Alanine aminotransferase 2.	Glutamate dehydrogenase, mitochondrial; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.964
MS3_01289	MS3_00663	A0A095AGW3	A0A094ZDU3	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Aspartate aminotransferase, cytoplasmic.	0.948
MS3_01289	MS3_02399	A0A095AGW3	A0A094ZJR5	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Glutaminase kidney isoform, mitochondrial.	0.921