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GJA8 GJA8 MIF MIF ALDH1A1 ALDH1A1 FBN3 FBN3 KCNS3 KCNS3 BFSP2 BFSP2 TXNIP TXNIP LIM2 LIM2 CRYGS CRYGS CLCN3 CLCN3 KCNS1 KCNS1 EYA2 EYA2 KCNB1 KCNB1 CRYGB CRYGB CRYGC CRYGC CRYGA CRYGA CRYBB3 CRYBB3 CRYBB2 CRYBB2 CLCN4 CLCN4 BFSP1 BFSP1 DNASE2B DNASE2B TMEM114 TMEM114 NPR3 NPR3 GLRX GLRX EYA4 EYA4 CRYAA CRYAA STX4 STX4 VSX2 VSX2 HDAC9 HDAC9 CLNS1A CLNS1A MIP MIP PSIP1 PSIP1 KCNC1 KCNC1 OPTC OPTC HRH1 HRH1 CHRM5 CHRM5 CRYBB1 CRYBB1 ENSNLEP00000027899 ENSNLEP00000027899 LGSN LGSN ENSNLEP00000029526 ENSNLEP00000029526 KCNMA1 KCNMA1 TXN2 TXN2 LOC100593245 LOC100593245 KCNAB2 KCNAB2 LOC100595437 LOC100595437 ENSNLEP00000037515 ENSNLEP00000037515 CLCN7 CLCN7 FBN2 FBN2 CLCN2 CLCN2 ENSNLEP00000046431 ENSNLEP00000046431 TXN TXN CRYGD CRYGD BTBD6 BTBD6 GJA3 GJA3 ENSNLEP00000049027 ENSNLEP00000049027
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GJA8Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (433 aa)
MIFMacrophage migration inhibitory factor. (115 aa)
ALDH1A1Aldehyde dehydrogenase 1 family member A1; Belongs to the aldehyde dehydrogenase family. (501 aa)
FBN3Fibrillin 3. (2684 aa)
KCNS3Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family. (491 aa)
BFSP2Beaded filament structural protein 2; Belongs to the intermediate filament family. (415 aa)
TXNIPThioredoxin interacting protein. (391 aa)
LIM2Lens intrinsic membrane protein 2. (191 aa)
CRYGSCrystallin gamma S; Belongs to the beta/gamma-crystallin family. (178 aa)
CLCN3Chloride channel protein. (866 aa)
KCNS1Potassium voltage-gated channel modifier subfamily S member 1; Belongs to the potassium channel family. (529 aa)
EYA2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (512 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
CRYGBCrystallin gamma B; Belongs to the beta/gamma-crystallin family. (175 aa)
CRYGCCrystallin gamma C; Belongs to the beta/gamma-crystallin family. (174 aa)
CRYGACrystallin gamma A; Belongs to the beta/gamma-crystallin family. (174 aa)
CRYBB3Crystallin beta B3; Belongs to the beta/gamma-crystallin family. (211 aa)
CRYBB2Crystallin beta B2; Belongs to the beta/gamma-crystallin family. (205 aa)
CLCN4Chloride channel protein. (760 aa)
BFSP1Beaded filament structural protein 1; Belongs to the intermediate filament family. (653 aa)
DNASE2BDeoxyribonuclease 2 beta. (361 aa)
TMEM114Uncharacterized protein. (122 aa)
NPR3Natriuretic peptide receptor 3. (537 aa)
GLRXGlutaredoxin. (106 aa)
EYA4Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (645 aa)
CRYAASHSP domain-containing protein; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (173 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (297 aa)
VSX2Visual system homeobox 2. (361 aa)
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1066 aa)
CLNS1AChloride nucleotide-sensitive channel 1A. (237 aa)
MIPMajor intrinsic protein of lens fiber; Belongs to the MIP/aquaporin (TC 1.A.8) family. (256 aa)
PSIP1PC4 and SFRS1 interacting protein 1. (530 aa)
KCNC1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (585 aa)
OPTCOpticin. (332 aa)
HRH1Histamine receptor H1; Belongs to the G-protein coupled receptor 1 family. (487 aa)
CHRM5Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (532 aa)
CRYBB1Crystallin beta B1; Belongs to the beta/gamma-crystallin family. (252 aa)
ENSNLEP00000027899Uncharacterized protein. (172 aa)
LGSNLengsin, lens protein with glutamine synthetase domain; Belongs to the glutamine synthetase family. (514 aa)
ENSNLEP00000029526Uncharacterized protein. (173 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1289 aa)
TXN2Thioredoxin domain-containing protein. (186 aa)
LOC100593245Uncharacterized protein; Belongs to the beta/gamma-crystallin family. (176 aa)
KCNAB2Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (409 aa)
LOC100595437Thioredoxin domain-containing protein. (105 aa)
ENSNLEP00000037515Thioredoxin; Belongs to the thioredoxin family. (105 aa)
CLCN7CBS domain-containing protein. (909 aa)
FBN2Fibrillin 2. (2858 aa)
CLCN2Chloride channel protein. (898 aa)
ENSNLEP00000046431Thioredoxin; Belongs to the thioredoxin family. (101 aa)
TXNThioredoxin domain-containing protein. (97 aa)
CRYGDUncharacterized protein; Belongs to the beta/gamma-crystallin family. (174 aa)
BTBD6BTB domain containing 6. (410 aa)
GJA3Gap junction protein alpha 3. (419 aa)
ENSNLEP00000049027Thioredoxin domain-containing protein. (90 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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