STRINGSTRING
FGF2 FGF2 PECAM1 PECAM1 ICAM1 ICAM1 VCAM1 VCAM1 NOS3 NOS3 CDH5 CDH5 TNF TNF KDR KDR SELE SELE AKT1 AKT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (287 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (721 aa)
ICAM1Intercellular adhesion molecule 1. (531 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1128 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (687 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1367 aa)
SELESelectin E. (612 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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