STRINGSTRING
LSS LSS CYP7B1 CYP7B1 SIGMAR1 SIGMAR1 TM7SF2 TM7SF2 SQLE SQLE NSDHL NSDHL DHCR24 DHCR24 HSD17B7 HSD17B7 FDFT1 FDFT1 ERG28 ERG28 FAXDC2 FAXDC2 CH25H CH25H DHCR7 DHCR7 MSMO1 MSMO1 HMGCS1 HMGCS1 CYP51A1 CYP51A1 SC5D SC5D HMGCR HMGCR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LSSTerpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (672 aa)
CYP7B1Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (506 aa)
SIGMAR1Sigma non-opioid intracellular receptor 1. (223 aa)
TM7SF2Transmembrane 7 superfamily member 2. (380 aa)
SQLESqualene epoxidase. (574 aa)
NSDHLNAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (373 aa)
DHCR2424-dehydrocholesterol reductase. (514 aa)
HSD17B7Hydroxysteroid 17-beta dehydrogenase 7. (366 aa)
FDFT1Farnesyl-diphosphate farnesyltransferase 1. (480 aa)
ERG28Ergosterol biosynthesis 28 homolog. (140 aa)
FAXDC2Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. (310 aa)
CH25HCholesterol 25-hydroxylase; Belongs to the sterol desaturase family. (272 aa)
DHCR77-dehydrocholesterol reductase. (475 aa)
MSMO1Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. (293 aa)
HMGCS13-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (520 aa)
CYP51A1Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family. (509 aa)
SC5DSterol-C5-desaturase; Belongs to the sterol desaturase family. (299 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (893 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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