STRINGSTRING
LZTR1 LZTR1 CRKL CRKL CACNG5 CACNG5 KSR2 KSR2 PEBP1 PEBP1 RASL11A RASL11A BRAP BRAP DOCK1 DOCK1 KALRN KALRN CRK CRK RALB RALB KSR1 KSR1 PAK2 PAK2 RASGEF1C RASGEF1C BRAF BRAF TCHP TCHP ELMO1 ELMO1 PAK6 PAK6 ARHGEF6 ARHGEF6 RALA RALA MAP2K2 MAP2K2 MCF2 MCF2 ARHGDIB ARHGDIB RAP1A RAP1A MRAS MRAS ELMO3 ELMO3 YWHAH YWHAH ARHGEF28 ARHGEF28 DOCK2 DOCK2 KRAS KRAS MYO9B MYO9B RAPGEF4 RAPGEF4 SIPA1 SIPA1 ARFIP1 ARFIP1 FHDC1 FHDC1 ARRDC2 ARRDC2 RIN1 RIN1 YWHAB YWHAB INKA1 INKA1 MTCL1 MTCL1 RALBP1 RALBP1 CASS4 CASS4 ARHGEF16 ARHGEF16 RASL11B RASL11B HRAS HRAS PSTPIP1 PSTPIP1 RASA4B RASA4B RASGRF1 RASGRF1 ARHGAP15 ARHGAP15 GTDC1 GTDC1 G1RDR4_NOMLE G1RDR4_NOMLE REM1 REM1 PLEK PLEK SYDE2 SYDE2 ARHGDIA ARHGDIA ARHGAP29 ARHGAP29 DOCK4 DOCK4 AKAP13 AKAP13 RASGRP1 RASGRP1 BNIP2 BNIP2 RND2 RND2 IQGAP1 IQGAP1 RIT1 RIT1 RGL3 RGL3 IQGAP2 IQGAP2 RASL12 RASL12 RAPGEF1 RAPGEF1 ARHGEF11 ARHGEF11 LPXN LPXN RALGDS RALGDS RASGRF2 RASGRF2 YWHAQ YWHAQ RASA1 RASA1 MARK1 MARK1 MYO9A MYO9A USP21 USP21 ARHGAP1 ARHGAP1 PAK5 PAK5 PAK4 PAK4 GNA13 GNA13 EFS EFS CBY1 CBY1 IPCEF1 IPCEF1 SHOC2 SHOC2 RAC1 RAC1 RASGEF1A RASGEF1A DIAPH3 DIAPH3 FGD1 FGD1 PTK2B PTK2B AKNA AKNA APBB1IP APBB1IP RASGRP4 RASGRP4 SPRED3 SPRED3 RALGPS1 RALGPS1 GP1BA GP1BA GARNL3 GARNL3 RRAS2 RRAS2 RGL1 RGL1 RABIF RABIF MOS MOS SFN SFN ERAS ERAS LOC100581805 LOC100581805 RASA2 RASA2 MDM4 MDM4 PREX1 PREX1 RAF1 RAF1 RHOQ RHOQ PKN1 PKN1 TRIO TRIO CNKSR3 CNKSR3 ENSNLEP00000026050 ENSNLEP00000026050 GP1BB GP1BB ENSNLEP00000026622 ENSNLEP00000026622 ABR ABR RASAL2 RASAL2 RAP1GAP2 RAP1GAP2 GNA12 GNA12 SPRED1 SPRED1 LOC100593129 LOC100593129 ENSNLEP00000027935 ENSNLEP00000027935 AKT1 AKT1 ARAF ARAF MARK4 MARK4 YWHAZ YWHAZ ARL9 ARL9 CNKSR1 CNKSR1 RAP1GAP RAP1GAP ENSNLEP00000029280 ENSNLEP00000029280 ENSNLEP00000029711 ENSNLEP00000029711 NCK2 NCK2 RHOU RHOU ARHGEF3 ARHGEF3 IQGAP3 IQGAP3 SSPO SSPO ELMO2 ELMO2 ENSNLEP00000034316 ENSNLEP00000034316 ENSNLEP00000034935 ENSNLEP00000034935 CDC25B CDC25B MAP2K1 MAP2K1 RHOG RHOG ENSNLEP00000036455 ENSNLEP00000036455 ENSNLEP00000036737 ENSNLEP00000036737 RASGRP2 RASGRP2 PAK3 PAK3 CIT CIT RAP2B RAP2B RIT2 RIT2 BAD BAD DOCK3 DOCK3 ARL1 ARL1 ENSNLEP00000038791 ENSNLEP00000038791 RTKN RTKN ARHGAP12 ARHGAP12 ENSNLEP00000039177 ENSNLEP00000039177 PAK1 PAK1 ENSNLEP00000039561 ENSNLEP00000039561 ENSNLEP00000039626 ENSNLEP00000039626 ARHGEF7 ARHGEF7 RGL2 RGL2 SPRED2 SPRED2 NF1 NF1 NRAS NRAS GIT2 GIT2 CDC42 CDC42 ENSNLEP00000040885 ENSNLEP00000040885 MARK3 MARK3 RHOB RHOB BCAR1 BCAR1 GIT1 GIT1 RAC2 RAC2 ARHGEF12 ARHGEF12 BEX3 BEX3 ENSNLEP00000042609 ENSNLEP00000042609 ENSNLEP00000042936 ENSNLEP00000042936 YWHAE YWHAE RAC3 RAC3 ARFIP2 ARFIP2 RHOF RHOF GMIP GMIP LOC100583245 LOC100583245 MLF1 MLF1 KIAA0930 KIAA0930 DIRAS2 DIRAS2 KHSRP KHSRP MUC2 MUC2 RHOC RHOC ENSNLEP00000047355 ENSNLEP00000047355 TRIM13 TRIM13 ENSNLEP00000048056 ENSNLEP00000048056 ENSNLEP00000048384 ENSNLEP00000048384 ENSNLEP00000048405 ENSNLEP00000048405 DIRAS3 DIRAS3 MARK2 MARK2 SRC SRC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LZTR1Leucine zipper like transcription regulator 1. (835 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (275 aa)
KSR2Kinase suppressor of ras 2. (950 aa)
PEBP1Phosphatidylethanolamine binding protein 1. (150 aa)
RASL11ARAS like family 11 member A. (242 aa)
BRAPBRCA1 associated protein. (521 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1886 aa)
KALRNUncharacterized protein. (2931 aa)
CRKUncharacterized protein. (252 aa)
RALBRAS like proto-oncogene B. (212 aa)
KSR1Kinase suppressor of ras 1. (831 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
RASGEF1CRasGEF domain family member 1C. (449 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (764 aa)
TCHPTrichoplein keratin filament binding. (498 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (776 aa)
RALARAS like proto-oncogene A. (206 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (383 aa)
MCF2MCF.2 cell line derived transforming sequence. (1001 aa)
ARHGDIBRho GDP dissociation inhibitor beta. (201 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
MRASMuscle RAS oncogene homolog. (208 aa)
ELMO3Engulfment and cell motility 3. (694 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa)
ARHGEF28Rho guanine nucleotide exchange factor 28. (1731 aa)
DOCK2Dedicator of cytokinesis 2; Belongs to the DOCK family. (1830 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2151 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (925 aa)
SIPA1Signal-induced proliferation-associated 1. (1022 aa)
ARFIP1ADP ribosylation factor interacting protein 1. (373 aa)
FHDC1FH2 domain containing 1. (1122 aa)
ARRDC2Arrestin domain containing 2. (414 aa)
RIN1Ras and Rab interactor 1. (782 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
INKA1Inka box actin regulator 1. (287 aa)
MTCL1Microtubule crosslinking factor 1. (1675 aa)
RALBP1RalA binding protein 1. (655 aa)
CASS4Cas scaffold protein family member 4. (786 aa)
ARHGEF16Uncharacterized protein. (509 aa)
RASL11BRAS like family 11 member B. (248 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PSTPIP1Proline-serine-threonine phosphatase interacting protein 1. (407 aa)
RASA4BRas-GAP domain-containing protein. (727 aa)
RASGRF1Ras protein specific guanine nucleotide releasing factor 1. (1243 aa)
ARHGAP15Rho GTPase activating protein 15. (475 aa)
GTDC1Glycosyltransferase like domain containing 1. (444 aa)
G1RDR4_NOMLEJ domain-containing protein. (287 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
PLEKPleckstrin. (350 aa)
SYDE2Synapse defective Rho GTPase homolog 2. (1194 aa)
ARHGDIAUncharacterized protein. (162 aa)
ARHGAP29Rho GTPase activating protein 29. (1265 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (2019 aa)
AKAP13A-kinase anchoring protein 13. (2761 aa)
RASGRP1RAS guanyl releasing protein 1. (785 aa)
BNIP2BCL2 interacting protein 2. (435 aa)
RND2Rho family GTPase 2. (227 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1657 aa)
RIT1Ras like without CAAX 1. (236 aa)
RGL3Ral guanine nucleotide dissociation stimulator like 3. (610 aa)
IQGAP2IQ motif containing GTPase activating protein 2. (1575 aa)
RASL12Uncharacterized protein. (227 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1110 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1557 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (387 aa)
RALGDSUncharacterized protein. (916 aa)
RASGRF2Ras protein specific guanine nucleotide releasing factor 2. (1232 aa)
YWHAQ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (253 aa)
RASA1RAS p21 protein activator 1. (1047 aa)
MARK1Non-specific serine/threonine protein kinase. (770 aa)
MYO9AMyosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2548 aa)
USP21Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (566 aa)
ARHGAP1Rho GTPase activating protein 1. (439 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
PAK4Non-specific serine/threonine protein kinase. (595 aa)
GNA13G protein subunit alpha 13. (373 aa)
EFSEmbryonal Fyn-associated substrate. (561 aa)
CBY1Chibby family member 1, beta catenin antagonist. (161 aa)
IPCEF1Interaction protein for cytohesin exchange factors 1. (438 aa)
SHOC2SHOC2 leucine rich repeat scaffold protein. (582 aa)
RAC1Rac family small GTPase 1. (187 aa)
RASGEF1ARasGEF domain family member 1A. (449 aa)
DIAPH3Diaphanous related formin 3. (1147 aa)
FGD1FYVE, RhoGEF and PH domain containing 1. (962 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (871 aa)
AKNAAT-hook transcription factor. (1395 aa)
APBB1IPAmyloid beta precursor protein binding family B member 1 interacting protein. (667 aa)
RASGRP4RAS guanyl releasing protein 4. (673 aa)
SPRED3Uncharacterized protein. (438 aa)
RALGPS1Ral GEF with PH domain and SH3 binding motif 1. (557 aa)
GP1BAGlycoprotein Ib platelet subunit alpha. (679 aa)
GARNL3GTPase activating Rap/RanGAP domain like 3. (1004 aa)
RRAS2RAS related 2. (204 aa)
RGL1Ral guanine nucleotide dissociation stimulator like 1. (770 aa)
RABIFRAB interacting factor. (123 aa)
MOSMOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (346 aa)
SFNStratifin; Belongs to the 14-3-3 family. (248 aa)
ERASES cell expressed Ras. (233 aa)
LOC100581805Uncharacterized protein. (1144 aa)
RASA2RAS p21 protein activator 2. (849 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (490 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1537 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
RHOQUncharacterized protein. (190 aa)
PKN1Protein kinase domain-containing protein. (839 aa)
TRIOTrio Rho guanine nucleotide exchange factor. (3026 aa)
CNKSR3CNKSR family member 3. (555 aa)
ENSNLEP0000002605014_3_3 domain-containing protein; Belongs to the 14-3-3 family. (241 aa)
GP1BBGlycoprotein Ib platelet subunit beta. (206 aa)
ENSNLEP0000002662214_3_3 domain-containing protein; Belongs to the 14-3-3 family. (230 aa)
ABRABR activator of RhoGEF and GTPase. (847 aa)
RASAL2RAS protein activator like 2. (1280 aa)
RAP1GAP2RAP1 GTPase activating protein 2. (774 aa)
GNA12G protein subunit alpha 12. (381 aa)
SPRED1Sprouty related EVH1 domain containing 1. (444 aa)
LOC100593129Rhodanese domain-containing protein. (501 aa)
ENSNLEP00000027935Uncharacterized protein. (181 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
ARAFUncharacterized protein. (664 aa)
MARK4Non-specific serine/threonine protein kinase. (638 aa)
YWHAZ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa)
ARL9Uncharacterized protein. (184 aa)
CNKSR1PH domain-containing protein. (621 aa)
RAP1GAPRAP1 GTPase activating protein. (696 aa)
ENSNLEP0000002928014_3_3 domain-containing protein; Belongs to the 14-3-3 family. (230 aa)
ENSNLEP00000029711Uncharacterized protein. (230 aa)
NCK2Cytoplasmic protein. (380 aa)
RHOURas homolog family member U. (258 aa)
ARHGEF3Rho guanine nucleotide exchange factor 3. (537 aa)
IQGAP3Uncharacterized protein. (2344 aa)
SSPOSCO-spondin. (4903 aa)
ELMO2Engulfment and cell motility 2. (720 aa)
ENSNLEP00000034316Uncharacterized protein. (188 aa)
ENSNLEP00000034935Uncharacterized protein. (310 aa)
CDC25BRhodanese domain-containing protein. (485 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
RHOGRas homolog family member G. (191 aa)
ENSNLEP00000036455Uncharacterized protein. (127 aa)
ENSNLEP00000036737Uncharacterized protein. (160 aa)
RASGRP2RAS guanyl releasing protein 2. (610 aa)
PAK3P21 (RAC1) activated kinase 3. (580 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2048 aa)
RAP2BRAP2B, member of RAS oncogene family. (183 aa)
RIT2Ras like without CAAX 2. (217 aa)
BADUncharacterized protein. (82 aa)
DOCK3Dedicator of cytokinesis 3; Belongs to the DOCK family. (1987 aa)
ARL1ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family. (164 aa)
ENSNLEP00000038791Uncharacterized protein. (63 aa)
RTKNRhotekin. (563 aa)
ARHGAP12Rho GTPase activating protein 12. (846 aa)
ENSNLEP0000003917714_3_3 domain-containing protein; Belongs to the 14-3-3 family. (207 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
ENSNLEP0000003956114_3_3 domain-containing protein; Belongs to the 14-3-3 family. (247 aa)
ENSNLEP00000039626Uncharacterized protein. (116 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (747 aa)
RGL2Ral guanine nucleotide dissociation stimulator like 2. (766 aa)
SPRED2Sprouty related EVH1 domain containing 2. (418 aa)
NF1Neurofibromin 1. (2839 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
GIT2GIT ArfGAP 2. (760 aa)
CDC42Cell division cycle 42. (191 aa)
ENSNLEP00000040885Uncharacterized protein. (113 aa)
MARK3Non-specific serine/threonine protein kinase. (784 aa)
RHOBRas homolog family member B. (196 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (827 aa)
GIT1GIT ArfGAP 1. (772 aa)
RAC2Rac family small GTPase 2. (192 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1544 aa)
BEX3Brain expressed X-linked 3. (121 aa)
ENSNLEP00000042609Uncharacterized protein. (168 aa)
ENSNLEP00000042936Protein kinase domain-containing protein. (201 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
RAC3Rac family small GTPase 3. (205 aa)
ARFIP2ADP ribosylation factor interacting protein 2. (374 aa)
RHOFRas homolog family member F, filopodia associated. (211 aa)
GMIPUncharacterized protein. (867 aa)
LOC10058324514_3_3 domain-containing protein; Belongs to the 14-3-3 family. (224 aa)
MLF1Myeloid leukemia factor 1. (298 aa)
KIAA0930KIAA0930. (343 aa)
DIRAS2DIRAS family GTPase 2. (199 aa)
KHSRPKH-type splicing regulatory protein. (651 aa)
MUC2Uncharacterized protein. (1539 aa)
RHOCRas homolog family member C. (209 aa)
ENSNLEP00000047355Rho-GAP domain-containing protein. (519 aa)
TRIM13Tripartite motif containing 13. (410 aa)
ENSNLEP00000048056Uncharacterized protein. (115 aa)
ENSNLEP00000048384Rho-GAP domain-containing protein. (552 aa)
ENSNLEP00000048405Uncharacterized protein. (167 aa)
DIRAS3DIRAS family GTPase 3. (229 aa)
MARK2Non-specific serine/threonine protein kinase. (788 aa)
SRCTyrosine-protein kinase. (537 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (18%) [HD]