STRINGSTRING
TNIP2 TNIP2 IKBKE IKBKE SQSTM1 SQSTM1 RELB RELB TANK TANK TRAF5 TRAF5 IRAK3 IRAK3 NFKBIE NFKBIE NFKBIA NFKBIA CD180 CD180 AZI2 AZI2 TRADD TRADD IRAK2 IRAK2 MYD88 MYD88 PELI3 PELI3 UNC93B1 UNC93B1 ZBP1 ZBP1 G1R620_NOMLE G1R620_NOMLE BIRC3 BIRC3 PRKCD PRKCD MLKL MLKL CARD9 CARD9 G1R9T9_NOMLE G1R9T9_NOMLE MALT1 MALT1 TRAF2 TRAF2 TLR7 TLR7 TLR8 TLR8 PELI1 PELI1 CARD11 CARD11 TNIP1 TNIP1 RIPK1 RIPK1 TLR3 TLR3 LY86 LY86 TICAM2 TICAM2 PRKCQ PRKCQ IKBKB IKBKB PELI2 PELI2 TICAM1 TICAM1 NFKB1 NFKB1 MAP3K7 MAP3K7 IKBKG IKBKG G1RWX7_NOMLE G1RWX7_NOMLE CARD10 CARD10 TNFAIP3 TNFAIP3 NFKB2 NFKB2 TAB1 TAB1 TAB2 TAB2 RIPK3 RIPK3 TRAF3 TRAF3 ALPK1 ALPK1 PRKCE PRKCE TBK1 TBK1 TLR10 TLR10 TLR1 TLR1 TRAF1 TRAF1 MAP3K8 MAP3K8 IRAK4 IRAK4 TRAF6 TRAF6 TLR2 TLR2 IL1R1 IL1R1 TAX1BP1 TAX1BP1 TLR4 TLR4 CHUK CHUK REL REL ENSNLEP00000027432 ENSNLEP00000027432 RNF11 RNF11 TNFRSF1A TNFRSF1A LY96 LY96 MAP3K14 MAP3K14 CYLD CYLD TIFA TIFA TLR6 TLR6 RELA RELA BIRC2 BIRC2 ENSNLEP00000039390 ENSNLEP00000039390 BCL3 BCL3 BCL10 BCL10 TIRAP TIRAP TAB3 TAB3 MARCKS MARCKS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TNIP2CCHC NOA-type domain-containing protein. (322 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (676 aa)
SQSTM1UBA_5 domain-containing protein. (197 aa)
RELBRELB proto-oncogene, NF-kB subunit. (586 aa)
TANKTRAF family member associated NFKB activator. (425 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (596 aa)
NFKBIENFKB inhibitor epsilon. (487 aa)
NFKBIANFKB inhibitor alpha. (305 aa)
CD180CD180 molecule. (661 aa)
AZI25-azacytidine induced 2. (392 aa)
TRADDTNFRSF1A associated via death domain. (311 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (568 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (317 aa)
PELI3E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (469 aa)
UNC93B1Unc-93 homolog B1, TLR signaling regulator. (597 aa)
ZBP1Z-DNA binding protein 1. (429 aa)
G1R620_NOMLETIR domain-containing protein. (1031 aa)
BIRC3Baculoviral IAP repeat containing 3. (603 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
MLKLMixed lineage kinase domain like pseudokinase. (454 aa)
CARD9Caspase recruitment domain family member 9. (536 aa)
G1R9T9_NOMLEUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (784 aa)
MALT1MALT1 paracaspase. (824 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
TLR7Toll like receptor 7; Belongs to the Toll-like receptor family. (1049 aa)
TLR8Toll like receptor 8; Belongs to the Toll-like receptor family. (1041 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
CARD11Caspase recruitment domain family member 11. (1154 aa)
TNIP1TNFAIP3 interacting protein 1. (619 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (671 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa)
LY86Lymphocyte antigen 86. (162 aa)
TICAM2Toll like receptor adaptor molecule 2. (234 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (745 aa)
PELI2Pellino E3 ubiquitin protein ligase family member 2. (394 aa)
TICAM1TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (691 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
IKBKGNEMO domain-containing protein. (173 aa)
G1RWX7_NOMLEANK_REP_REGION domain-containing protein. (182 aa)
CARD10Caspase recruitment domain family member 10. (898 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
NFKB2Nuclear factor kappa B subunit 2. (900 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (506 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
ALPK1Alpha kinase 1. (1241 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
TBK1TANK binding kinase 1. (729 aa)
TLR10Toll like receptor 10; Belongs to the Toll-like receptor family. (811 aa)
TLR1Toll like receptor 1; Belongs to the Toll-like receptor family. (786 aa)
TRAF1TNF receptor-associated factor. (416 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (467 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (460 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
TLR2Toll-like receptor. (784 aa)
IL1R1Interleukin 1 receptor type 1. (569 aa)
TAX1BP1Tax1 binding protein 1. (813 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (832 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (743 aa)
RELREL proto-oncogene, NF-kB subunit. (619 aa)
ENSNLEP00000027432TNF receptor-associated factor. (488 aa)
RNF11RING-type domain-containing protein. (131 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
LY96Lymphocyte antigen 96. (160 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (939 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa)
TIFATRAF interacting protein with forkhead associated domain. (185 aa)
TLR6TIR domain-containing protein. (472 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
BIRC2Baculoviral IAP repeat containing 2. (615 aa)
ENSNLEP00000039390Protein kinase domain-containing protein. (673 aa)
BCL3BCL3 transcription coactivator. (453 aa)
BCL10CARD domain-containing protein. (319 aa)
TIRAPTIR domain containing adaptor protein. (221 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa)
MARCKSMyristoylated alanine rich protein kinase C substrate. (328 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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