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NIFK NIFK RRP1B RRP1B PES1 PES1 FTSJ3 FTSJ3 WDR74 WDR74 NOP2 NOP2 NIP7 NIP7 WDR12 WDR12 GNL3 GNL3 RPF1 RPF1 RSL1D1 RSL1D1 GNL2 GNL2 NOC3L NOC3L EBNA1BP2 EBNA1BP2 GNL3L GNL3L LOC100587940 LOC100587940 MAK16 MAK16 BRIX1 BRIX1 GTPBP4 GTPBP4 RRS1 RRS1 ENSNLEP00000043918 ENSNLEP00000043918 RPF2 RPF2 MRTO4 MRTO4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NIFKNucleolar protein interacting with the FHA domain of MKI67. (293 aa)
RRP1BRibosomal RNA processing 1B. (729 aa)
PES1Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. (577 aa)
FTSJ3pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (840 aa)
WDR74WD repeat domain 74. (385 aa)
NOP2SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (813 aa)
NIP760S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (180 aa)
WDR12Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (423 aa)
GNL3G protein nucleolar 3. (548 aa)
RPF1Ribosome production factor 1 homolog. (316 aa)
RSL1D1Uncharacterized protein. (490 aa)
GNL2Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (730 aa)
NOC3LNucleolar complex protein 3 homolog. (789 aa)
EBNA1BP2Uncharacterized protein. (262 aa)
GNL3LG protein nucleolar 3 like. (582 aa)
LOC100587940Uncharacterized protein. (704 aa)
MAK16Protein MAK16 homolog; Belongs to the MAK16 family. (300 aa)
BRIX1Biogenesis of ribosomes BRX1. (339 aa)
GTPBP4Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (634 aa)
RRS1Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (328 aa)
ENSNLEP00000043918Uncharacterized protein. (381 aa)
RPF2Ribosome production factor 2 homolog. (306 aa)
MRTO4Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (222 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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