STRINGSTRING
LRPAP1 LRPAP1 GSKIP GSKIP SOX17 SOX17 TCF7L1 TCF7L1 APC2 APC2 NLK NLK SCRIB SCRIB FOXN1 FOXN1 KREMEN1 KREMEN1 WNT5B WNT5B ATCAY ATCAY WIF1 WIF1 LRP6 LRP6 RYK RYK FZD6 FZD6 LRP12 LRP12 WNT2B WNT2B LRP2 LRP2 PRICKLE4 PRICKLE4 WNT3 WNT3 WNT9B WNT9B G1QYG1_NOMLE G1QYG1_NOMLE CERT1 CERT1 SOST SOST CTNNB1 CTNNB1 ZNF649 ZNF649 SFRP2 SFRP2 LRP5 LRP5 WNT5A WNT5A ARHGEF19 ARHGEF19 PRICKLE3 PRICKLE3 WNT4 WNT4 VLDLR VLDLR LRP1B LRP1B WNT6 WNT6 WNT10A WNT10A RELN RELN WLS WLS CTNNBIP1 CTNNBIP1 KREMEN2 KREMEN2 OGFR OGFR UCKL1 UCKL1 LOC100596171 LOC100596171 GSK3A GSK3A NKD2 NKD2 APC APC WNT2 WNT2 WNT16 WNT16 DKK1 DKK1 SFRP1 SFRP1 UCK1 UCK1 DKK4 DKK4 CSNK1G2 CSNK1G2 DACT1 DACT1 DAAM1 DAAM1 VANGL2 VANGL2 WNT7B WNT7B WNT9A WNT9A G1RVW8_NOMLE G1RVW8_NOMLE PCSK9 PCSK9 DAB1 DAB1 WNT8B WNT8B AXIN2 AXIN2 ROR1 ROR1 TCF7L2 TCF7L2 G1S229_NOMLE G1S229_NOMLE BARX1 BARX1 FZD3 FZD3 WNT11 WNT11 DKK3 DKK3 WNT1 WNT1 PRICKLE1 PRICKLE1 LRP8 LRP8 FZD9 FZD9 FZD10 FZD10 FRAT2 FRAT2 DVL3 DVL3 GSK3B GSK3B WNT3A WNT3A DAAM2 DAAM2 AMER1 AMER1 PORCN PORCN LRP5L LRP5L ENSNLEP00000029616 ENSNLEP00000029616 ENSNLEP00000030555 ENSNLEP00000030555 FZD7 FZD7 PTPRU PTPRU LDLRAP1 LDLRAP1 ANKRD42 ANKRD42 LEF1 LEF1 FZD4 FZD4 PRICKLE2 PRICKLE2 OGFRL1 OGFRL1 WNT8A WNT8A NKD1 NKD1 SNX20 SNX20 LRP1 LRP1 VANGL1 VANGL1 GOLPH3L GOLPH3L LDLR LDLR CSNK1G1 CSNK1G1 PTCHD3 PTCHD3 DKK2 DKK2 ANKRD6 ANKRD6 CSNK1G3 CSNK1G3 DVL1 DVL1 DVL2 DVL2 FZD2 FZD2 CSNK1A1 CSNK1A1 CER1 CER1 WNT10B WNT10B FZD5 FZD5 TCF7 TCF7 ENSNLEP00000047555 ENSNLEP00000047555 SFRP4 SFRP4 AXIN1 AXIN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRPAP1LDL receptor related protein associated protein 1. (350 aa)
GSKIPGSK3B interacting protein. (144 aa)
SOX17SRY-box transcription factor 17. (410 aa)
TCF7L1Transcription factor 7 like 1. (517 aa)
APC2APC regulator of WNT signaling pathway 2. (1906 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
SCRIBScribble planar cell polarity protein. (1449 aa)
FOXN1Forkhead box N1. (648 aa)
KREMEN1Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (492 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
ATCAYATCAY kinesin light chain interacting caytaxin. (333 aa)
WIF1WNT inhibitory factor 1. (379 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
RYKReceptor like tyrosine kinase. (525 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
LRP12LDL receptor related protein 12. (859 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
LRP2LDL receptor related protein 2. (4624 aa)
PRICKLE4Uncharacterized protein. (385 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
G1QYG1_NOMLEProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (323 aa)
CERT1Ceramide transporter 1. (747 aa)
SOSTSclerostin. (213 aa)
CTNNB1Catenin beta 1. (781 aa)
ZNF649Zinc finger protein 649. (475 aa)
SFRP2Secreted frizzled related protein 2. (280 aa)
LRP5LDL receptor related protein 5. (1510 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
ARHGEF19Rho guanine nucleotide exchange factor 19. (770 aa)
PRICKLE3Uncharacterized protein. (501 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (207 aa)
VLDLRVery low density lipoprotein receptor. (873 aa)
LRP1BLDL receptor related protein 1B. (4598 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
RELNReelin. (3460 aa)
WLSWnt ligand secretion mediator. (542 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
KREMEN2Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (462 aa)
OGFROGFr_N domain-containing protein. (455 aa)
UCKL1Uridine-cytidine kinase; Belongs to the uridine kinase family. (539 aa)
LOC100596171Uncharacterized protein. (143 aa)
GSK3AGlycogen synthase kinase 3 alpha. (439 aa)
NKD2EF-hand domain-containing protein. (388 aa)
APCAPC regulator of WNT signaling pathway. (2844 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
DKK1Dickkopf-like protein 1. (266 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
UCK1Uridine-cytidine kinase 1. (281 aa)
DKK4Dickkopf WNT signaling pathway inhibitor 4. (224 aa)
CSNK1G2Protein kinase domain-containing protein. (379 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (837 aa)
DAAM1Dishevelled associated activator of morphogenesis 1. (1036 aa)
VANGL2Uncharacterized protein. (435 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
G1RVW8_NOMLEUncharacterized protein. (281 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9. (693 aa)
DAB1DAB adaptor protein 1. (588 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
AXIN2DIX domain-containing protein. (294 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa)
TCF7L2HMG box domain-containing protein. (534 aa)
G1S229_NOMLEUncharacterized protein. (279 aa)
BARX1BARX homeobox 1. (288 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
DKK3Dickkopf WNT signaling pathway inhibitor 3. (321 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
PRICKLE1Prickle planar cell polarity protein 1. (831 aa)
LRP8LDL receptor related protein 8. (924 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
FZD10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
FRAT2FRAT regulator of WNT signaling pathway 2. (232 aa)
DVL3Dishevelled segment polarity protein 3. (673 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
DAAM2Dishevelled associated activator of morphogenesis 2. (1012 aa)
AMER1Uncharacterized protein. (805 aa)
PORCNPorcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (461 aa)
LRP5LUncharacterized protein. (150 aa)
ENSNLEP00000029616RGS domain-containing protein. (169 aa)
ENSNLEP00000030555Protein kinase domain-containing protein. (200 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
PTPRUProtein tyrosine phosphatase receptor type U. (1326 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (299 aa)
ANKRD42Ankyrin repeat domain 42. (527 aa)
LEF1Lymphoid enhancer binding factor 1. (386 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (540 aa)
PRICKLE2Prickle planar cell polarity protein 2. (886 aa)
OGFRL1Opioid growth factor receptor like 1. (434 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
NKD1NKD inhibitor of WNT signaling pathway 1. (470 aa)
SNX20Sorting nexin 20. (316 aa)
LRP1LDL receptor related protein 1. (4219 aa)
VANGL1Vang-like protein. (524 aa)
GOLPH3LGolgi phosphoprotein 3 like. (285 aa)
LDLRUncharacterized protein. (839 aa)
CSNK1G1Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. (475 aa)
PTCHD3Patched domain containing 3. (769 aa)
DKK2Dickkopf WNT signaling pathway inhibitor 2. (259 aa)
ANKRD6Ankyrin repeat domain 6. (727 aa)
CSNK1G3Casein kinase 1 gamma 3; Belongs to the protein kinase superfamily. (455 aa)
DVL1Dishevelled segment polarity protein 1. (667 aa)
DVL2Dishevelled segment polarity protein 2. (713 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (543 aa)
CSNK1A1Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (365 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (335 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
TCF7HMG box domain-containing protein. (486 aa)
ENSNLEP00000047555Protein kinase domain-containing protein. (341 aa)
SFRP4Secreted frizzled related protein 4. (369 aa)
AXIN1Axin 1. (837 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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