STRINGSTRING
POLR2E POLR2E GTF2F2 GTF2F2 POLR2C POLR2C LOC100582721 LOC100582721 GTF2E1 GTF2E1 GTF2H4 GTF2H4 POLR2L POLR2L POLR2B POLR2B POLR2A POLR2A GTF2B GTF2B POLR2I POLR2I GTF2E2 GTF2E2 MNAT1 MNAT1 ERCC3 ERCC3 GTF2F1 GTF2F1 MED28 MED28 GTF2H1 GTF2H1 G1SA94_NOMLE G1SA94_NOMLE POLR2D POLR2D ERCC2 ERCC2 ENSNLEP00000028300 ENSNLEP00000028300 POLR2H POLR2H GTF2H5 GTF2H5 ENSNLEP00000033138 ENSNLEP00000033138 POLR2G POLR2G GTF2A1 GTF2A1 CDK7 CDK7 ENSNLEP00000039234 ENSNLEP00000039234 POLR2K POLR2K GTF2H3 GTF2H3 CCNH CCNH POLR2J POLR2J ENSNLEP00000047803 ENSNLEP00000047803 POLR2F POLR2F
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLR2ERNA polymerase II subunit E. (211 aa)
GTF2F2General transcription factor IIF subunit 2. (239 aa)
POLR2CRNA polymerase II subunit C. (248 aa)
LOC100582721General transcription factor IIH subunit. (395 aa)
GTF2E1General transcription factor IIE subunit 1. (439 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1164 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1960 aa)
GTF2BGeneral transcription factor IIB. (316 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
GTF2E2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (291 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (737 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (511 aa)
MED28Uncharacterized protein. (223 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
G1SA94_NOMLEUncharacterized protein. (55 aa)
POLR2DRNA polymerase II subunit D. (154 aa)
ERCC2Helicase ATP-binding domain-containing protein. (625 aa)
ENSNLEP00000028300TFIIA_gamma_N domain-containing protein. (56 aa)
POLR2HRNA polymerase II subunit H. (174 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
ENSNLEP00000033138Protein kinase domain-containing protein. (310 aa)
POLR2GS1 domain-containing protein. (189 aa)
GTF2A1General transcription factor IIA subunit 1. (376 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (341 aa)
ENSNLEP00000039234Uncharacterized protein. (193 aa)
POLR2KUncharacterized protein. (77 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
POLR2JUncharacterized protein. (56 aa)
ENSNLEP00000047803BSD domain-containing protein. (524 aa)
POLR2FUncharacterized protein. (177 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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