STRINGSTRING
ENSNLEP00000047355 ENSNLEP00000047355 ZW10 ZW10 TOPORS TOPORS ENSNLEP00000048077 ENSNLEP00000048077 ENSNLEP00000048384 ENSNLEP00000048384 RASSF1 RASSF1 TUBGCP5 TUBGCP5 KATNB1 KATNB1 DCTN1 DCTN1 NEK6 NEK6 ENSNLEP00000049000 ENSNLEP00000049000 SBDS SBDS RMDN1 RMDN1 LATS2 LATS2 FBF1 FBF1 CDC6 CDC6 SMC6 SMC6 PLK5 PLK5 MISP MISP BCCIP BCCIP ABRAXAS2 ABRAXAS2 BOD1 BOD1 NPM1 NPM1 ALMS1 ALMS1 TACC3 TACC3 RGS14 RGS14 KIF11 KIF11 KIF20B KIF20B NIN NIN PLK1 PLK1 PPP2CB PPP2CB CDC14A CDC14A TUBG1 TUBG1 WDR62 WDR62 WDR73 WDR73 HAUS1 HAUS1 G1RJG4_NOMLE G1RJG4_NOMLE KATNBL1 KATNBL1 ANKRD53 ANKRD53 MAPRE1 MAPRE1 FAM161A FAM161A IK IK TMEM201 TMEM201 G1RDL6_NOMLE G1RDL6_NOMLE CEP85 CEP85 AUNIP AUNIP MAD2L1 MAD2L1 NUBP2 NUBP2 KLHL21 KLHL21 G1RB97_NOMLE G1RB97_NOMLE CTDP1 CTDP1 FAM110C FAM110C CEP104 CEP104 KLHL22 KLHL22 CEP89 CEP89 RAE1 RAE1 AURKA AURKA RALBP1 RALBP1 MTCL1 MTCL1 CEP44 CEP44 TBCCD1 TBCCD1 NEDD1 NEDD1 CTNNB1 CTNNB1 HAUS8 HAUS8 VPS4A VPS4A CCDC155 CCDC155 TUBGCP4 TUBGCP4 RAD21 RAD21 NUDCD2 NUDCD2 EFCAB3 EFCAB3 DYNC1LI1 DYNC1LI1 STAG1 STAG1 CCNB1 CCNB1 CEP63 CEP63 PLEKHG6 PLEKHG6 TOPBP1 TOPBP1 SGO1 SGO1 RMDN3 RMDN3 KIF2A KIF2A CALM3 CALM3 PSRC1 PSRC1 NEK2 NEK2 RSKR RSKR SPAG5 SPAG5 TTC28 TTC28 UNC119 UNC119 KNTC1 KNTC1 GPSM2 GPSM2 TUBGCP2 TUBGCP2 CDC20 CDC20 PLK3 PLK3 IKBKG IKBKG CENPF CENPF BRCC3 BRCC3 CEP95 CEP95 KATNA1 KATNA1 LATS1 LATS1 YPEL5 YPEL5 SPAST SPAST DYNC1I1 DYNC1I1 BOD1L1 BOD1L1 ALPK1 ALPK1 CEP128 CEP128 CDK5RAP2 CDK5RAP2 CNTRL CNTRL NUMA1 NUMA1 SPOUT1 SPOUT1 AAAS AAAS ASPM ASPM NEK7 NEK7 CEP19 CEP19 SMC3 SMC3 KATNAL1 KATNAL1 FRY FRY MAPK14 MAPK14 ENSNLEP00000025379 ENSNLEP00000025379 CETN1 CETN1 UXT UXT ENSNLEP00000026532 ENSNLEP00000026532 KATNAL2 KATNAL2 UMOD UMOD ENSNLEP00000027802 ENSNLEP00000027802 LOC100593129 LOC100593129 TUBGCP3 TUBGCP3 BOD1L2 BOD1L2 ENSNLEP00000028618 ENSNLEP00000028618 CKAP5 CKAP5 ENSNLEP00000029090 ENSNLEP00000029090 ODF2 ODF2 CALM1 CALM1 ENSNLEP00000030327 ENSNLEP00000030327 AURKC AURKC ENSNLEP00000031417 ENSNLEP00000031417 CDC14B CDC14B LOC101178681 LOC101178681 EFCAB13 EFCAB13 NDE1 NDE1 LRMP LRMP EFHC1 EFHC1 EML1 EML1 CDC25B CDC25B ENSNLEP00000035652 ENSNLEP00000035652 BIRC6 BIRC6 POC1B POC1B ENSNLEP00000036942 ENSNLEP00000036942 ENSNLEP00000036988 ENSNLEP00000036988 KAT5 KAT5 DDX11 DDX11 ENSNLEP00000037698 ENSNLEP00000037698 SPDL1 SPDL1 LOC100584516 LOC100584516 AURKB AURKB CSPP1 CSPP1 HSF1 HSF1 GOLGA2 GOLGA2 TNKS TNKS NEDD9 NEDD9 ARHGEF7 ARHGEF7 ENSNLEP00000039968 ENSNLEP00000039968 PRC1 PRC1 FAM83D FAM83D PPP2CA PPP2CA GIT1 GIT1 HNRNPU HNRNPU TPX2 TPX2 CALM2 CALM2 ENSNLEP00000042051 ENSNLEP00000042051 ENSNLEP00000042675 ENSNLEP00000042675 MAPKBP1 MAPKBP1 ENSNLEP00000043133 ENSNLEP00000043133 UBXN2B UBXN2B STAG2 STAG2 BEX4 BEX4 KNSTRN KNSTRN ENSNLEP00000045860 ENSNLEP00000045860 TUBGCP6 TUBGCP6 RMDN2 RMDN2 DLGAP5 DLGAP5 ENSNLEP00000046801 ENSNLEP00000046801 PKP4 PKP4 POC1A POC1A SMC1A SMC1A CUL3 CUL3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSNLEP00000047355Rho-GAP domain-containing protein. (519 aa)
ZW10Zw10 kinetochore protein. (699 aa)
TOPORSTOP1 binding arginine/serine rich protein. (1053 aa)
ENSNLEP00000048077Uncharacterized protein. (458 aa)
ENSNLEP00000048384Rho-GAP domain-containing protein. (552 aa)
RASSF1Ras association domain family member 1. (304 aa)
TUBGCP5Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (1026 aa)
KATNB1Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...] (654 aa)
DCTN1CAP-Gly domain-containing protein. (1280 aa)
NEK6NIMA related kinase 6; Belongs to the protein kinase superfamily. (347 aa)
ENSNLEP00000049000Uncharacterized protein. (110 aa)
SBDSSBDS ribosome maturation factor. (250 aa)
RMDN1Regulator of microtubule dynamics 1. (314 aa)
LATS2Non-specific serine/threonine protein kinase. (1084 aa)
FBF1Uncharacterized protein. (936 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (560 aa)
SMC6Structural maintenance of chromosomes 6. (1091 aa)
PLK5Polo like kinase 5. (324 aa)
MISPMitotic spindle positioning. (673 aa)
BCCIPBRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family. (325 aa)
ABRAXAS2Abraxas 2, BRISC complex subunit. (414 aa)
BOD1Biorientation of chromosomes in cell division 1. (185 aa)
NPM1Nucleophosmin 1. (294 aa)
ALMS1ALMS1 centrosome and basal body associated protein. (4052 aa)
TACC3Transforming acidic coiled-coil containing protein 3. (807 aa)
RGS14Regulator of G protein signaling 14. (565 aa)
KIF11Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1056 aa)
KIF20BKinesin family member 20B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1822 aa)
NINNinein. (2133 aa)
PLK1Serine/threonine-protein kinase PLK. (568 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
CDC14ACell division cycle 14A. (594 aa)
TUBG1Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (464 aa)
WDR62WD repeat domain 62. (1345 aa)
WDR73WD repeat domain 73. (372 aa)
HAUS1HAUS augmin like complex subunit 1. (278 aa)
G1RJG4_NOMLEDynein assembly factor 1, axonemal. (655 aa)
KATNBL1Katanin regulatory subunit B1 like 1. (304 aa)
ANKRD53Ankyrin repeat domain 53. (529 aa)
MAPRE1Microtubule associated protein RP/EB family member 1. (268 aa)
FAM161AFAM161 centrosomal protein A. (716 aa)
IKIK cytokine. (537 aa)
TMEM201Transmembrane protein 201. (637 aa)
G1RDL6_NOMLEUncharacterized protein. (279 aa)
CEP85Centrosomal protein 85. (761 aa)
AUNIPAurora kinase A and ninein interacting protein. (358 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (205 aa)
NUBP2Cytosolic Fe-S cluster assembly factor NUBP2; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (271 aa)
KLHL21Kelch like family member 21. (587 aa)
G1RB97_NOMLEUncharacterized protein. (503 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (951 aa)
FAM110CFamily with sequence similarity 110 member C. (321 aa)
CEP104Centrosomal protein 104. (887 aa)
KLHL22Kelch like family member 22. (558 aa)
CEP89Centrosomal protein 89. (719 aa)
RAE1Ribonucleic acid export 1. (303 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (403 aa)
RALBP1RalA binding protein 1. (655 aa)
MTCL1Microtubule crosslinking factor 1. (1675 aa)
CEP44Centrosomal protein 44. (399 aa)
TBCCD1TBCC domain containing 1. (557 aa)
NEDD1NEDD1 gamma-tubulin ring complex targeting factor. (660 aa)
CTNNB1Catenin beta 1. (781 aa)
HAUS8HAUS augmin like complex subunit 8. (409 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (506 aa)
CCDC155Coiled-coil domain containing 155. (564 aa)
TUBGCP4Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (667 aa)
RAD21RAD21 cohesin complex component. (631 aa)
NUDCD2CS domain-containing protein. (129 aa)
EFCAB3EF-hand calcium binding domain 3. (449 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (523 aa)
STAG1Stromal antigen 1. (1258 aa)
CCNB1Cyclin B1; Belongs to the cyclin family. (429 aa)
CEP63Centrosomal protein 63. (703 aa)
PLEKHG6Pleckstrin homology and RhoGEF domain containing G6. (790 aa)
TOPBP1DNA topoisomerase II binding protein 1. (1527 aa)
SGO1Shugoshin 1. (559 aa)
RMDN3Regulator of microtubule dynamics 3. (470 aa)
KIF2AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (732 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (147 aa)
PSRC1Proline and serine rich coiled-coil 1. (348 aa)
NEK2NIMA related kinase 2. (445 aa)
RSKRRibosomal protein S6 kinase related. (410 aa)
SPAG5Sperm associated antigen 5. (1200 aa)
TTC28Tetratricopeptide repeat domain 28. (2295 aa)
UNC119Unc-119 lipid binding chaperone. (240 aa)
KNTC1Kinetochore associated 1. (2189 aa)
GPSM2G protein signaling modulator 2. (684 aa)
TUBGCP2Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (830 aa)
CDC20Cell division cycle 20. (498 aa)
PLK3Polo like kinase 3. (641 aa)
IKBKGNEMO domain-containing protein. (173 aa)
CENPFCentromere protein F. (3113 aa)
BRCC3BRCA1/BRCA2-containing complex subunit 3. (317 aa)
CEP95Centrosomal protein 95. (820 aa)
KATNA1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (491 aa)
LATS1Large tumor suppressor kinase 1. (1130 aa)
YPEL5Protein yippee-like; Belongs to the yippee family. (121 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (616 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (645 aa)
BOD1L1Biorientation of chromosomes in cell division 1 like 1. (3048 aa)
ALPK1Alpha kinase 1. (1241 aa)
CEP128Centrosomal protein 128. (1094 aa)
CDK5RAP2CDK5 regulatory subunit associated protein 2. (1920 aa)
CNTRLCentriolin. (2325 aa)
NUMA1Uncharacterized protein. (947 aa)
SPOUT1SPOUT domain containing methyltransferase 1. (376 aa)
AAASAladin WD repeat nucleoporin. (546 aa)
ASPMAbnormal spindle microtubule assembly. (3388 aa)
NEK7NIMA related kinase 7; Belongs to the protein kinase superfamily. (302 aa)
CEP19Centrosomal protein 19. (167 aa)
SMC3Structural maintenance of chromosomes protein. (1191 aa)
KATNAL1Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...] (490 aa)
FRYFRY microtubule binding protein. (3016 aa)
MAPK14Mitogen-activated protein kinase. (321 aa)
ENSNLEP00000025379Uncharacterized protein. (95 aa)
CETN1Uncharacterized protein. (157 aa)
UXTUncharacterized protein. (169 aa)
ENSNLEP00000026532Uncharacterized protein. (390 aa)
KATNAL2Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (538 aa)
UMODUromodulin. (676 aa)
ENSNLEP00000027802Uncharacterized protein. (223 aa)
LOC100593129Rhodanese domain-containing protein. (501 aa)
TUBGCP3Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (909 aa)
BOD1L2Biorientation of chromosomes in cell division 1 like 2. (171 aa)
ENSNLEP00000028618WD_REPEATS_REGION domain-containing protein. (470 aa)
CKAP5Cytoskeleton associated protein 5. (2040 aa)
ENSNLEP00000029090Uncharacterized protein. (278 aa)
ODF2Outer dense fiber of sperm tails 2. (829 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (150 aa)
ENSNLEP00000030327HORMA domain-containing protein. (98 aa)
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (309 aa)
ENSNLEP00000031417Nsp1_C domain-containing protein. (440 aa)
CDC14BCell division cycle 14B. (462 aa)
LOC101178681Uncharacterized protein. (661 aa)
EFCAB13EF-hand calcium binding domain 13. (855 aa)
NDE1NudE neurodevelopment protein 1. (349 aa)
LRMPUncharacterized protein. (1435 aa)
EFHC1EF-hand domain containing 1. (641 aa)
EML1EMAP like 1. (817 aa)
CDC25BRhodanese domain-containing protein. (485 aa)
ENSNLEP00000035652Uncharacterized protein; Belongs to the calmodulin family. (123 aa)
BIRC6Baculoviral IAP repeat containing 6. (4924 aa)
POC1BPOC1 centriolar protein B. (478 aa)
ENSNLEP00000036942Uncharacterized protein; Belongs to the calmodulin family. (123 aa)
ENSNLEP00000036988Nucleoplasmin domain-containing protein. (224 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (535 aa)
DDX11DEAD/H-box helicase 11. (965 aa)
ENSNLEP00000037698Uncharacterized protein. (134 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (595 aa)
LOC100584516Uncharacterized protein. (306 aa)
AURKBUncharacterized protein. (123 aa)
CSPP1Centrosome and spindle pole associated protein 1. (1111 aa)
HSF1HSF_DOMAIN domain-containing protein. (272 aa)
GOLGA2Golgin A2. (1005 aa)
TNKSPoly [ADP-ribose] polymerase. (1312 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (838 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (747 aa)
ENSNLEP00000039968Nucleoplasmin domain-containing protein. (274 aa)
PRC1Protein regulator of cytokinesis 1. (620 aa)
FAM83DFamily with sequence similarity 83 member D. (613 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
GIT1GIT ArfGAP 1. (772 aa)
HNRNPUB30.2/SPRY domain-containing protein. (725 aa)
TPX2TPX2 microtubule nucleation factor. (783 aa)
CALM2Uncharacterized protein; Belongs to the calmodulin family. (196 aa)
ENSNLEP00000042051Uncharacterized protein. (448 aa)
ENSNLEP00000042675Uncharacterized protein. (89 aa)
MAPKBP1Mitogen-activated protein kinase binding protein 1. (1514 aa)
ENSNLEP00000043133Uncharacterized protein. (256 aa)
UBXN2BUBX domain protein 2B. (331 aa)
STAG2Stromal antigen 2. (1268 aa)
BEX4Brain expressed X-linked 4. (120 aa)
KNSTRNUncharacterized protein. (238 aa)
ENSNLEP00000045860Uncharacterized protein. (64 aa)
TUBGCP6Uncharacterized protein. (1442 aa)
RMDN2Regulator of microtubule dynamics 2. (573 aa)
DLGAP5DLG associated protein 5. (815 aa)
ENSNLEP00000046801Protein kinase domain-containing protein. (214 aa)
PKP4Plakophilin 4. (1202 aa)
POC1APOC1 centriolar protein A. (369 aa)
SMC1AStructural maintenance of chromosomes protein. (1230 aa)
CUL3Cullin 3; Belongs to the cullin family. (744 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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