60 items (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PLEKHA2	Pleckstrin homology domain containing A2. (425 aa)
	MAP4K4	Mitogen-activated protein kinase kinase kinase kinase 4. (1346 aa)
	THY1	Ig-like domain-containing protein. (216 aa)
	ENSNLEP00000041273	Uncharacterized protein. (190 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	CD3E	CD3e molecule. (198 aa)
	EMP2	Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
	ENSNLEP00000042609	Uncharacterized protein. (168 aa)
	CDK6	Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
	NRP1	Neuropilin; Belongs to the neuropilin family. (901 aa)
	GSK3B	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa)
	ENSNLEP00000027935	Uncharacterized protein. (181 aa)
	MYOC	Myocilin. (526 aa)
	UTRN	Utrophin. (3434 aa)
	PTPRJ	Protein tyrosine phosphatase receptor type J. (1282 aa)
	FERMT1	Fermitin family member 1. (587 aa)
	S100A10	S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa)
	TSC1	TSC complex subunit 1. (1164 aa)
	SFRP1	Secreted frizzled related protein 1. (314 aa)
	ABL1	Tyrosine-protein kinase. (1006 aa)
	CIB1	Uncharacterized protein. (187 aa)
	JUP	Junction plakoglobin. (730 aa)
	CCL28	C-C motif chemokine. (127 aa)
	RIN2	Ras and Rab interactor 2. (930 aa)
	HPSE	Heparanase. (543 aa)
	DAG1	Dystroglycan 1. (895 aa)
	SDC4	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (198 aa)
	HRG	Histidine rich glycoprotein. (530 aa)
	RRAS	RAS related. (217 aa)
	CCL25	SCY domain-containing protein. (131 aa)
	CCL21	C-C motif chemokine ligand 21. (134 aa)
	CSF1	Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (554 aa)
	EPHA1	EPH receptor A1. (975 aa)
	CX3CL1	C-X3-C motif chemokine ligand 1. (397 aa)
	SKAP1	Src kinase associated phosphoprotein 1. (359 aa)
	DISC1	Uncharacterized protein. (202 aa)
	TSTA3	Tissue specific transplantation antigen P35B. (320 aa)
	EPB41L5	Erythrocyte membrane protein band 4.1 like 5. (732 aa)
	PRKCZ	Protein kinase C zeta. (507 aa)
	CEACAM6	Carcinoembryonic antigen related cell adhesion molecule 6. (310 aa)
	LIMS1	LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (397 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (806 aa)
	VEGFA	Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (393 aa)
	G1SAU3_NOMLE	L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (338 aa)
	NINJ1	Ninjurin 1. (152 aa)
	TEK	TEK receptor tyrosine kinase. (1124 aa)
	PTK2B	Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (871 aa)
	RAC1	Rac family small GTPase 1. (187 aa)
	PPM1F	Protein phosphatase, Mg2+/Mn2+ dependent 1F. (454 aa)
	POLDIP2	DNA polymerase delta interacting protein 2. (368 aa)
	ROCK1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1359 aa)
	KDR	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1367 aa)
	CCR7	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
	CD36	CD36 molecule; Belongs to the CD36 family. (433 aa)
	ITGB1BP1	Integrin subunit beta 1 binding protein 1. (200 aa)
	EFEMP2	EGF containing fibulin extracellular matrix protein 2. (456 aa)
	COL16A1	LAM_G_DOMAIN domain-containing protein. (1472 aa)
	DMD	Dystrophin. (3685 aa)
	FMN1	Formin 1. (1424 aa)
	FERMT2	Fermitin family member 2. (693 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	CDK6	ENSNLEP00000015256	ENSNLEP00000024323	Tyrosine-protein kinase.	Cyclin dependent kinase 6; Belongs to the protein kinase superfamily.	0.443
ABL1	ENSNLEP00000027935	ENSNLEP00000015256	ENSNLEP00000027935	Tyrosine-protein kinase.	Uncharacterized protein.	0.450
ABL1	ENSNLEP00000042609	ENSNLEP00000015256	ENSNLEP00000042609	Tyrosine-protein kinase.	Uncharacterized protein.	0.450
ABL1	JUP	ENSNLEP00000015256	ENSNLEP00000013440	Tyrosine-protein kinase.	Junction plakoglobin.	0.586
ABL1	RAC1	ENSNLEP00000015256	ENSNLEP00000019034	Tyrosine-protein kinase.	Rac family small GTPase 1.	0.450
CCL21	CCL25	ENSNLEP00000005795	ENSNLEP00000028433	C-C motif chemokine ligand 21.	SCY domain-containing protein.	0.802
CCL21	CCL28	ENSNLEP00000005795	ENSNLEP00000012681	C-C motif chemokine ligand 21.	C-C motif chemokine.	0.987
CCL21	CCR7	ENSNLEP00000005795	ENSNLEP00000044671	C-C motif chemokine ligand 21.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.998
CCL21	CX3CL1	ENSNLEP00000005795	ENSNLEP00000003473	C-C motif chemokine ligand 21.	C-X3-C motif chemokine ligand 1.	0.779
CCL25	CCL21	ENSNLEP00000028433	ENSNLEP00000005795	SCY domain-containing protein.	C-C motif chemokine ligand 21.	0.802
CCL25	CCL28	ENSNLEP00000028433	ENSNLEP00000012681	SCY domain-containing protein.	C-C motif chemokine.	0.491
CCL25	CCR7	ENSNLEP00000028433	ENSNLEP00000044671	SCY domain-containing protein.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.960
CCL25	CX3CL1	ENSNLEP00000028433	ENSNLEP00000003473	SCY domain-containing protein.	C-X3-C motif chemokine ligand 1.	0.576
CCL28	CCL21	ENSNLEP00000012681	ENSNLEP00000005795	C-C motif chemokine.	C-C motif chemokine ligand 21.	0.987
CCL28	CCL25	ENSNLEP00000012681	ENSNLEP00000028433	C-C motif chemokine.	SCY domain-containing protein.	0.491
CCL28	CCR7	ENSNLEP00000012681	ENSNLEP00000044671	C-C motif chemokine.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.759
CCR7	CCL21	ENSNLEP00000044671	ENSNLEP00000005795	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine ligand 21.	0.998
CCR7	CCL25	ENSNLEP00000044671	ENSNLEP00000028433	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	SCY domain-containing protein.	0.960
CCR7	CCL28	ENSNLEP00000044671	ENSNLEP00000012681	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine.	0.759
CCR7	CD3E	ENSNLEP00000044671	ENSNLEP00000042028	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	CD3e molecule.	0.588

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