STRINGSTRING
CDK5 CDK5 SLC6A2 SLC6A2 DRD3 DRD3 ADORA2A ADORA2A RASD2 RASD2 SNCA SNCA CRHBP CRHBP DRD2 DRD2 CRH CRH ENSNLEP00000034296 ENSNLEP00000034296 ENSNLEP00000036861 ENSNLEP00000036861 DRD1 DRD1 PARK7 PARK7 TH TH PRKN PRKN SLC6A3 SLC6A3 DRD4 DRD4 ENSNLEP00000029188 ENSNLEP00000029188
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa)
SLC6A2Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (628 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (400 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
RASD2RASD family member 2. (266 aa)
SNCAAlpha-synuclein; Belongs to the synuclein family. (140 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (445 aa)
CRHCorticotropin releasing hormone. (196 aa)
ENSNLEP00000034296DJ-1_PfpI domain-containing protein. (133 aa)
ENSNLEP00000036861Uncharacterized protein. (119 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
THTyrosine hydroxylase. (507 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (437 aa)
SLC6A3Solute carrier family 6 member 3. (552 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (386 aa)
ENSNLEP00000029188Uncharacterized protein. (60 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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