STRINGSTRING
TH TH NR4A2 NR4A2 EDN1 EDN1 PPP1R1B PPP1R1B HPRT1 HPRT1 RGS7 RGS7 EDNRA EDNRA OXT OXT DRD4 DRD4 TRDMT1 TRDMT1 DBH DBH ADORA2A ADORA2A SLC18A2 SLC18A2 PDE1B PDE1B NR4A1 NR4A1 RGS2 RGS2 DRD2 DRD2 CALM1 CALM1 PPP3CA PPP3CA PPP1R9B PPP1R9B HDAC2 HDAC2 DRD1 DRD1 ASIC1 ASIC1 GRIN2A GRIN2A SLC1A1 SLC1A1 OXTR OXTR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
THTyrosine hydroxylase. (507 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (598 aa)
EDN1Endothelin 1. (211 aa)
PPP1R1BProtein phosphatase 1 regulatory inhibitor subunit 1B. (204 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
RGS7Regulator of G protein signaling 7. (487 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (124 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (386 aa)
TRDMT1tRNA aspartic acid methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (393 aa)
DBHDopamine beta-hydroxylase. (611 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
SLC18A2Solute carrier family 18 member A2. (514 aa)
PDE1BPhosphodiesterase. (536 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (589 aa)
RGS2Regulator of G protein signaling 2. (211 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (445 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (150 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
PPP1R9BProtein phosphatase 1 regulatory subunit 9B. (813 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (533 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
ASIC1Acid sensing ion channel subunit 1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (479 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
SLC1A1Amino acid transporter. (457 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (389 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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