STRINGSTRING
GLRX3 GLRX3 NOS1 NOS1 MYL2 MYL2 NOS3 NOS3 MYL4 MYL4 GRK2 GRK2 MYL10 MYL10 SLC9A1 SLC9A1 EDN2 EDN2 PLN PLN SLC8A1 SLC8A1 CAV1 CAV1 ATP1A1 ATP1A1 ENSNLEP00000035899 ENSNLEP00000035899 CAMK2D CAMK2D ADRA1A ADRA1A RYR2 RYR2 ATP2A2 ATP2A2 ATP1A2 ATP1A2 MYL3 MYL3 ADRB1 ADRB1 ATP2B4 ATP2B4 CSRP3 CSRP3 ADM ADM CHGA CHGA GAA GAA MYH7 MYH7 MYH6 MYH6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GLRX3Uncharacterized protein. (335 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1425 aa)
MYL2Myosin light chain 2. (166 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1128 aa)
MYL4Myosin light chain 4. (195 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (589 aa)
MYL10Myosin light chain 10. (226 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (809 aa)
EDN2Endothelin 2. (177 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (972 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
ENSNLEP00000035899Uncharacterized protein. (321 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
ADRA1AAdrenoceptor alpha 1A. (470 aa)
RYR2Ryanodine receptor 2. (4825 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
MYL3EF-hand domain-containing protein. (161 aa)
ADRB1Adrenoceptor beta 1. (476 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1241 aa)
CSRP3Cysteine and glycine rich protein 3. (194 aa)
ADMAdrenomedullin. (184 aa)
CHGAChromogranin A. (460 aa)
GAAGlucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family. (932 aa)
MYH7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1899 aa)
MYH6Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1823 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.