41 items (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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gene fusions

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protein homology

Your Input:
	C1GALT1	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Glycosyltransferase that generates the core 1 O-glycan Gal- beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins; Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily. (363 aa)
	NKX3-2	NK3 homeobox 2. (341 aa)
	GDF11	TGF_BETA_2 domain-containing protein. (377 aa)
	BHLHA15	Basic helix-loop-helix family member a15. (189 aa)
	CDK6	Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
	ENSNLEP00000026885	Uncharacterized protein. (333 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (737 aa)
	YAP1	Uncharacterized protein. (418 aa)
	ENSNLEP00000032543	Uncharacterized protein. (168 aa)
	LOC100593010	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (459 aa)
	TIGAR	TP53 induced glycolysis regulatory phosphatase. (270 aa)
	RFX3	Regulatory factor X3. (760 aa)
	PAX6	Uncharacterized protein. (456 aa)
	SIDT2	SID1 transmembrane family member 2. (808 aa)
	FZD5	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
	YIPF6	Protein YIPF. (236 aa)
	RARG	Retinoic acid receptor gamma. (441 aa)
	SRC	Tyrosine-protein kinase. (537 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (850 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	LOC100596750	Carrier domain-containing protein. (2303 aa)
	RARA	Retinoic acid receptor alpha. (458 aa)
	IL6ST	Interleukin 6 signal transducer. (918 aa)
	BMP5	Bone morphogenetic protein 5. (454 aa)
	RARB	Retinoic acid receptor beta. (448 aa)
	HNF4A	Hepatocyte nuclear factor 4 alpha. (473 aa)
	TYMS	Thymidylat_synt domain-containing protein. (173 aa)
	PGR	Uncharacterized protein. (339 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	SPDEF	SAM pointed domain containing ETS transcription factor. (335 aa)
	NKX6-1	NK6 homeobox 1. (368 aa)
	LOC100592336	PH_3 domain-containing protein. (247 aa)
	NKX2-2	NK2 homeobox 2. (273 aa)
	BMP6	TGF_BETA_2 domain-containing protein. (125 aa)
	SMO	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (683 aa)
	PRDM1	PR/SET domain 1. (825 aa)
	ROS1	Tyrosine-protein kinase receptor. (2347 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	FASN	Carrier domain-containing protein. (2417 aa)
	GATA2	GATA binding protein 2. (480 aa)
	SLC9A4	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (798 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	BMP5	ENSNLEP00000015368	ENSNLEP00000003942	Bone morphogenetic protein 4.	Bone morphogenetic protein 5.	0.688
BMP4	BMP6	ENSNLEP00000015368	ENSNLEP00000014208	Bone morphogenetic protein 4.	TGF_BETA_2 domain-containing protein.	0.968
BMP4	GATA2	ENSNLEP00000015368	ENSNLEP00000017404	Bone morphogenetic protein 4.	GATA binding protein 2.	0.404
BMP4	PAX6	ENSNLEP00000015368	ENSNLEP00000044058	Bone morphogenetic protein 4.	Uncharacterized protein.	0.459
BMP4	WNT5A	ENSNLEP00000015368	ENSNLEP00000008828	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.486
BMP5	BMP4	ENSNLEP00000003942	ENSNLEP00000015368	Bone morphogenetic protein 5.	Bone morphogenetic protein 4.	0.688
BMP6	BMP4	ENSNLEP00000014208	ENSNLEP00000015368	TGF_BETA_2 domain-containing protein.	Bone morphogenetic protein 4.	0.968
CDK6	GATA2	ENSNLEP00000024323	ENSNLEP00000017404	Cyclin dependent kinase 6; Belongs to the protein kinase superfamily.	GATA binding protein 2.	0.442
ENSNLEP00000032543	SRC	ENSNLEP00000032543	ENSNLEP00000048569	Uncharacterized protein.	Tyrosine-protein kinase.	0.772
FZD5	ROS1	ENSNLEP00000047338	ENSNLEP00000016224	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family.	Tyrosine-protein kinase receptor.	0.444
FZD5	WNT5A	ENSNLEP00000047338	ENSNLEP00000008828	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.995
GATA2	BMP4	ENSNLEP00000017404	ENSNLEP00000015368	GATA binding protein 2.	Bone morphogenetic protein 4.	0.404
GATA2	CDK6	ENSNLEP00000017404	ENSNLEP00000024323	GATA binding protein 2.	Cyclin dependent kinase 6; Belongs to the protein kinase superfamily.	0.442
GATA2	HIF1A	ENSNLEP00000017404	ENSNLEP00000048714	GATA binding protein 2.	Hypoxia inducible factor 1 subunit alpha.	0.470
GATA2	PGR	ENSNLEP00000017404	ENSNLEP00000008712	GATA binding protein 2.	Uncharacterized protein.	0.560
GATA2	RARA	ENSNLEP00000017404	ENSNLEP00000002184	GATA binding protein 2.	Retinoic acid receptor alpha.	0.521
HIF1A	GATA2	ENSNLEP00000048714	ENSNLEP00000017404	Hypoxia inducible factor 1 subunit alpha.	GATA binding protein 2.	0.470
HIF1A	HNF4A	ENSNLEP00000048714	ENSNLEP00000008037	Hypoxia inducible factor 1 subunit alpha.	Hepatocyte nuclear factor 4 alpha.	0.624
HIF1A	PGR	ENSNLEP00000048714	ENSNLEP00000008712	Hypoxia inducible factor 1 subunit alpha.	Uncharacterized protein.	0.532
HIF1A	PRDM1	ENSNLEP00000048714	ENSNLEP00000016062	Hypoxia inducible factor 1 subunit alpha.	PR/SET domain 1.	0.451

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