STRINGSTRING
CD8A CD8A LOC101178428 LOC101178428 NFKBIZ NFKBIZ BTN1A1 BTN1A1 SHB SHB CBLB CBLB ITK ITK MYO1G MYO1G TNFRSF21 TNFRSF21 PTPN22 PTPN22 STOML2 STOML2 BAX BAX COLEC10 COLEC10 PTPN6 PTPN6 PIK3CA PIK3CA FPR3 FPR3 G1R2B4_NOMLE G1R2B4_NOMLE KLHL6 KLHL6 EIF2B5 EIF2B5 SLA2 SLA2 NCR3 NCR3 BAG6 BAG6 PLCG1 PLCG1 BTNL2 BTNL2 CMKLR1 CMKLR1 HLA-DPB1 HLA-DPB1 YES1 YES1 CD28 CD28 CTLA4 CTLA4 PRKCD PRKCD CD3D CD3D CD3G CD3G BTK BTK FOXP3 FOXP3 INPP5D INPP5D HRAS HRAS SH2B2 SH2B2 MALT1 MALT1 FCN2 FCN2 LAT2 LAT2 ZNF683 ZNF683 PIK3CD PIK3CD BMX BMX RBCK1 RBCK1 MASP2 MASP2 FCN3 FCN3 G1REZ4_NOMLE G1REZ4_NOMLE HCK HCK CREBBP CREBBP LOC100593082 LOC100593082 PLCG2 PLCG2 CD19 CD19 ZC3H12A ZC3H12A GATA3 GATA3 MBL2 MBL2 ERMAP ERMAP ABL1 ABL1 IKBKB IKBKB MNDA MNDA BLNK BLNK CD79A CD79A EIF2B3 EIF2B3 IKBKG IKBKG CD276 CD276 CSK CSK FYB2 FYB2 PTPRJ PTPRJ CD247 CD247 CD79B CD79B RNF31 RNF31 RC3H1 RC3H1 BTNL8 BTNL8 NFAM1 NFAM1 SPPL3 SPPL3 EIF2B2 EIF2B2 PRKCE PRKCE PLEKHA1 PLEKHA1 NR4A3 NR4A3 MORN5 MORN5 RC3H2 RC3H2 TXK TXK TEC TEC PLD2 PLD2 CACNB3 CACNB3 TRAF6 TRAF6 DENND1B DENND1B PTPRC PTPRC C5AR1 C5AR1 M3Z9E6_NOMLE M3Z9E6_NOMLE BLK BLK FYB1 FYB1 FCER1G FCER1G VAV1 VAV1 ENSNLEP00000027244 ENSNLEP00000027244 MAPK1 MAPK1 TMEM269 TMEM269 ENSNLEP00000027432 ENSNLEP00000027432 CD38 CD38 PDE4B PDE4B PDE4D PDE4D CACNB4 CACNB4 LIME1 LIME1 ENSNLEP00000030682 ENSNLEP00000030682 PSEN1 PSEN1 MS4A1 MS4A1 ADA ADA MASP1 MASP1 ENSNLEP00000033188 ENSNLEP00000033188 FGR FGR VTCN1 VTCN1 NCKAP1L NCKAP1L MEF2C MEF2C PTK2 PTK2 FCHO1 FCHO1 CLEC7A CLEC7A NFATC2 NFATC2 LIMK1 LIMK1 EP300 EP300 BCL2 BCL2 PLA2G6 PLA2G6 LAX1 LAX1 FCN1 FCN1 ENSNLEP00000037391 ENSNLEP00000037391 HHLA2 HHLA2 PAK1 PAK1 EIF2B4 EIF2B4 ENSNLEP00000039713 ENSNLEP00000039713 FCGR2B FCGR2B THEMIS THEMIS BTN2A2 BTN2A2 PLPP4 PLPP4 BCL10 BCL10 TYROBP TYROBP ENSNLEP00000040897 ENSNLEP00000040897 FYN FYN THY1 THY1 BCAR1 BCAR1 FFAR2 FFAR2 CD3E CD3E ICOSLG ICOSLG ENSNLEP00000043131 ENSNLEP00000043131 PRKCB PRKCB HLA-DQB1 HLA-DQB1 WNK1 WNK1 GPLD1 GPLD1 ENSNLEP00000045542 ENSNLEP00000045542 RFTN1 RFTN1 SPG21 SPG21 LCP2 LCP2 VAV2 VAV2 SRC SRC EIF2B1 EIF2B1 CRKL CRKL SYK SYK CR2 CR2 LYN LYN STK11 STK11 VAV3 VAV3 ZAP70 ZAP70 PAK2 PAK2 C3AR1 C3AR1 PRAM1 PRAM1 RIPK2 RIPK2 KHDRBS1 KHDRBS1 BRAF BRAF LCK LCK BTNL3 BTNL3 SKAP1 SKAP1 BTNL9 BTNL9 PRKD2 PRKD2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CD8ACD8a molecule. (235 aa)
LOC101178428Uncharacterized protein. (156 aa)
NFKBIZNFKB inhibitor zeta. (718 aa)
BTN1A1Butyrophilin subfamily 1 member A1. (526 aa)
SHBSH2 domain-containing protein. (355 aa)
CBLBUncharacterized protein. (817 aa)
ITKTyrosine-protein kinase. (621 aa)
MYO1GMyosin IG; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1013 aa)
TNFRSF21TNF receptor superfamily member 21. (654 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (807 aa)
STOML2Stomatin like 2. (361 aa)
BAXUncharacterized protein. (194 aa)
COLEC10Collectin subfamily member 10. (277 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (627 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
FPR3Formyl peptide receptor 3. (319 aa)
G1R2B4_NOMLEIg-like domain-containing protein; Belongs to the MHC class I family. (370 aa)
KLHL6BTB domain-containing protein. (614 aa)
EIF2B5Eukaryotic translation initiation factor 2B subunit epsilon. (721 aa)
SLA2Src like adaptor 2. (261 aa)
NCR3Natural cytotoxicity triggering receptor 3. (190 aa)
BAG6BCL2 associated athanogene 6. (1119 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1182 aa)
BTNL2Butyrophilin like 2. (481 aa)
CMKLR1Chemerin chemokine-like receptor 1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
HLA-DPB1Major histocompatibility complex, class II, DP beta 1. (258 aa)
YES1Tyrosine-protein kinase. (519 aa)
CD28CD28 molecule. (220 aa)
CTLA4Cytotoxic T-lymphocyte associated protein 4. (223 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
CD3DCD3d molecule. (153 aa)
CD3GCD3g molecule. (182 aa)
BTKTyrosine-protein kinase. (659 aa)
FOXP3Forkhead box P3. (455 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1209 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
SH2B2Uncharacterized protein. (579 aa)
MALT1MALT1 paracaspase. (824 aa)
FCN2Ficolin 2. (313 aa)
LAT2Linker for activation of T cells family member 2. (244 aa)
ZNF683Zinc finger protein 683. (514 aa)
PIK3CDPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1077 aa)
BMXTyrosine-protein kinase. (675 aa)
RBCK1RANBP2-type and C3HC4-type zinc finger containing 1. (509 aa)
MASP2Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family. (685 aa)
FCN3Ficolin 3. (299 aa)
G1REZ4_NOMLECABIT domain-containing protein. (475 aa)
HCKTyrosine-protein kinase. (525 aa)
CREBBPCREB binding protein. (2442 aa)
LOC100593082Leukocyte immunoglobulin like receptor A2. (483 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1218 aa)
CD19CD19 molecule. (558 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (560 aa)
GATA3GATA binding protein 3. (444 aa)
MBL2Mannose binding lectin 2. (247 aa)
ERMAPErythroblast membrane associated protein (Scianna blood group). (475 aa)
ABL1Tyrosine-protein kinase. (1006 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (745 aa)
MNDAMyeloid cell nuclear differentiation antigen. (407 aa)
BLNKB cell linker. (403 aa)
CD79ACD79a molecule. (230 aa)
EIF2B3Eukaryotic translation initiation factor 2B subunit gamma. (435 aa)
IKBKGNEMO domain-containing protein. (173 aa)
CD276Uncharacterized protein. (299 aa)
CSKTyrosine-protein kinase. (274 aa)
FYB2FYN binding protein 2. (729 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1282 aa)
CD247CD247 molecule. (163 aa)
CD79BCD79b molecule. (229 aa)
RNF31Uncharacterized protein. (1072 aa)
RC3H1Ring finger and CCCH-type domains 1. (1133 aa)
BTNL8Butyrophilin like 8. (491 aa)
NFAM1NFAT activating protein with ITAM motif 1. (270 aa)
SPPL3Signal peptide peptidase like 3. (384 aa)
EIF2B2Eukaryotic translation initiation factor 2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (351 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
PLEKHA1Pleckstrin homology domain containing A1. (404 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (636 aa)
MORN5MORN repeat containing 5. (161 aa)
RC3H2Ring finger and CCCH-type domains 2. (1180 aa)
TXKTyrosine-protein kinase. (527 aa)
TECTyrosine-protein kinase. (631 aa)
PLD2Phospholipase. (933 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (444 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
DENND1BDENN domain containing 1B. (775 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1304 aa)
C5AR1Complement C5a receptor 1; Belongs to the G-protein coupled receptor 1 family. (350 aa)
M3Z9E6_NOMLEIg-like domain-containing protein. (148 aa)
BLKTyrosine-protein kinase. (505 aa)
FYB1FYN binding protein 1. (839 aa)
FCER1GUncharacterized protein. (112 aa)
VAV1Uncharacterized protein. (739 aa)
ENSNLEP00000027244Ig-like domain-containing protein; Belongs to the MHC class I family. (424 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
TMEM269Transmembrane protein 269. (203 aa)
ENSNLEP00000027432TNF receptor-associated factor. (488 aa)
CD38CD38 molecule. (300 aa)
PDE4BPhosphodiesterase. (736 aa)
PDE4DPhosphodiesterase. (748 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (502 aa)
LIME1Uncharacterized protein. (210 aa)
ENSNLEP00000030682Ig-like domain-containing protein. (159 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
MS4A1Membrane spanning 4-domains A1. (297 aa)
ADAAdenosine deaminase. (405 aa)
MASP1Mannan binding lectin serine peptidase 1; Belongs to the peptidase S1 family. (728 aa)
ENSNLEP00000033188Uncharacterized protein. (304 aa)
FGRTyrosine-protein kinase. (476 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (285 aa)
NCKAP1LNCK associated protein 1 like. (1109 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1099 aa)
FCHO1MHD domain-containing protein. (1076 aa)
CLEC7AC-type lectin domain containing 7A. (247 aa)
NFATC2Nuclear factor of activated T cells 2. (905 aa)
LIMK1Uncharacterized protein. (614 aa)
EP300E1A binding protein p300. (2306 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
PLA2G6Phospholipase A2 group VI. (805 aa)
LAX1Lymphocyte transmembrane adaptor 1. (368 aa)
FCN1Ficolin 1. (326 aa)
ENSNLEP00000037391Uncharacterized protein. (52 aa)
HHLA2HERV-H LTR-associating 2. (415 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
EIF2B4Eukaryotic translation initiation factor 2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (521 aa)
ENSNLEP00000039713Ig-like domain-containing protein. (361 aa)
FCGR2BUncharacterized protein. (310 aa)
THEMISThymocyte selection associated. (680 aa)
BTN2A2Butyrophilin subfamily 2 member A2. (523 aa)
PLPP4Phospholipid phosphatase 4. (279 aa)
BCL10CARD domain-containing protein. (319 aa)
TYROBPUncharacterized protein. (144 aa)
ENSNLEP00000040897Uncharacterized protein. (331 aa)
FYNTyrosine-protein kinase. (537 aa)
THY1Ig-like domain-containing protein. (216 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (827 aa)
FFAR2Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (330 aa)
CD3ECD3e molecule. (198 aa)
ICOSLGUncharacterized protein. (411 aa)
ENSNLEP00000043131Ig-like domain-containing protein. (186 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
HLA-DQB1Major histocompatibility complex, class II, DQ beta 1. (269 aa)
WNK1WNK lysine deficient protein kinase 1. (2833 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (840 aa)
ENSNLEP00000045542Ig-like domain-containing protein. (115 aa)
RFTN1Raftlin, lipid raft linker 1. (479 aa)
SPG21SPG21 abhydrolase domain containing, maspardin. (308 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
VAV2Vav guanine nucleotide exchange factor 2. (788 aa)
SRCTyrosine-protein kinase. (537 aa)
EIF2B1Eukaryotic translation initiation factor 2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family. (305 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
SYKTyrosine-protein kinase. (532 aa)
CR2Complement C3d receptor 2. (1092 aa)
LYNTyrosine-protein kinase. (512 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (423 aa)
VAV3Vav guanine nucleotide exchange factor 3. (799 aa)
ZAP70Tyrosine-protein kinase. (704 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
C3AR1Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family. (482 aa)
PRAM1SH3 domain-containing protein. (564 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
KHDRBS1KH domain-containing protein. (390 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (764 aa)
LCKLCK proto-oncogene, Src family tyrosine kinase. (448 aa)
BTNL3Butyrophilin like 3. (465 aa)
SKAP1Src kinase associated phosphoprotein 1. (359 aa)
BTNL9Butyrophilin like 9. (519 aa)
PRKD2Uncharacterized protein. (716 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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