21 items (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Your Input:
	FURIN	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (785 aa)
	SYK	Tyrosine-protein kinase. (532 aa)
	NOD2	Nucleotide binding oligomerization domain containing 2. (1040 aa)
	NLRP6	Pyrin domain-containing protein. (633 aa)
	GPR17	G protein-coupled receptor 17; Belongs to the G-protein coupled receptor 1 family. (366 aa)
	HCK	Tyrosine-protein kinase. (525 aa)
	PSMB4	Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
	MKRN2	Makorin ring finger protein 2. (417 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	FCGR2B	Uncharacterized protein. (310 aa)
	IL10	Interleukin 10. (178 aa)
	FGR	Tyrosine-protein kinase. (476 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	RHBDF2	Rhomboid 5 homolog 2. (751 aa)
	IL20RB	Interleukin 20 receptor subunit beta. (311 aa)
	IL12B	Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa)
	TREM2	Ig-like domain-containing protein. (222 aa)
	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1182 aa)
	YES1	Tyrosine-protein kinase. (519 aa)
	SRC	Tyrosine-protein kinase. (537 aa)
	SELENOS	Uncharacterized protein. (218 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FCGR2B	IL10	ENSNLEP00000040045	ENSNLEP00000033936	Uncharacterized protein.	Interleukin 10.	0.485
FCGR2B	LYN	ENSNLEP00000040045	ENSNLEP00000001435	Uncharacterized protein.	Tyrosine-protein kinase.	0.802
FCGR2B	SYK	ENSNLEP00000040045	ENSNLEP00000000530	Uncharacterized protein.	Tyrosine-protein kinase.	0.679
FGR	HCK	ENSNLEP00000033816	ENSNLEP00000011876	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.706
FGR	LYN	ENSNLEP00000033816	ENSNLEP00000001435	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.775
FGR	PLCG1	ENSNLEP00000033816	ENSNLEP00000007890	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.438
FGR	SRC	ENSNLEP00000033816	ENSNLEP00000048569	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.556
FGR	SYK	ENSNLEP00000033816	ENSNLEP00000000530	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.701
FGR	YES1	ENSNLEP00000033816	ENSNLEP00000008358	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.689
FURIN	IL10	ENSNLEP00000014749	ENSNLEP00000033936	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	Interleukin 10.	0.459
FYN	HCK	ENSNLEP00000041056	ENSNLEP00000011876	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.695
FYN	LYN	ENSNLEP00000041056	ENSNLEP00000001435	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.997
FYN	PLCG1	ENSNLEP00000041056	ENSNLEP00000007890	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.708
FYN	SRC	ENSNLEP00000041056	ENSNLEP00000048569	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.996
FYN	SYK	ENSNLEP00000041056	ENSNLEP00000000530	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.864
FYN	YES1	ENSNLEP00000041056	ENSNLEP00000008358	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.989
HCK	FGR	ENSNLEP00000011876	ENSNLEP00000033816	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.706
HCK	FYN	ENSNLEP00000011876	ENSNLEP00000041056	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.695
HCK	LYN	ENSNLEP00000011876	ENSNLEP00000001435	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.978
HCK	PLCG1	ENSNLEP00000011876	ENSNLEP00000007890	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.543

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