STRINGSTRING
NKX2-5 NKX2-5 TBX2 TBX2 TBX20 TBX20 ZFPM2 ZFPM2 TGFBR2 TGFBR2 LRP2 LRP2 GATA6 GATA6 ISL1 ISL1 SMAD4 SMAD4 BMP4 BMP4 TGFB2 TGFB2 SEMA3C SEMA3C FGF8 FGF8 FGFR2 FGFR2 PARVA PARVA NRP1 NRP1 ENG ENG BMPR1A BMPR1A ROBO2 ROBO2 ENSNLEP00000034753 ENSNLEP00000034753 ROBO1 ROBO1 BMPR2 BMPR2 NRP2 NRP2 SMAD6 SMAD6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NKX2-5NK2 homeobox 5. (317 aa)
TBX2T-box transcription factor 2. (647 aa)
TBX20T-box transcription factor 20. (447 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
LRP2LDL receptor related protein 2. (4624 aa)
GATA6Uncharacterized protein. (452 aa)
ISL1ISL LIM homeobox 1. (349 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (751 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (221 aa)
FGFR2Fibroblast growth factor receptor. (820 aa)
PARVAParvin alpha. (345 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (901 aa)
ENGEndoglin. (658 aa)
BMPR1ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
ROBO2Roundabout guidance receptor 2. (1199 aa)
ENSNLEP00000034753Uncharacterized protein. (428 aa)
ROBO1Roundabout guidance receptor 1. (1651 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (930 aa)
SMAD6Mothers against decapentaplegic homolog. (465 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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