STRINGSTRING
COL16A1 COL16A1 DMD DMD TLN1 TLN1 PTK2 PTK2 CCN4 CCN4 ICAM3 ICAM3 FERMT2 FERMT2 ITGAV ITGAV P4HB P4HB ITGA6 ITGA6 FGF2 FGF2 ACTN3 ACTN3 CXCL12 CXCL12 ITGA10 ITGA10 CD81 CD81 FRMD5 FRMD5 ENSNLEP00000040637 ENSNLEP00000040637 PLPP3 PLPP3 FBLN1 FBLN1 THY1 THY1 ENSNLEP00000041273 ENSNLEP00000041273 FBLN5 FBLN5 LAMA5 LAMA5 ENSNLEP00000042160 ENSNLEP00000042160 EMP2 EMP2 ITGA2 ITGA2 GFRA1 GFRA1 THBS1 THBS1 ENSNLEP00000044084 ENSNLEP00000044084 KDR KDR ENSNLEP00000044243 ENSNLEP00000044243 PTPN2 PTPN2 CD40LG CD40LG IL1B IL1B IGF1 IGF1 DST DST NRG1 NRG1 ITGB5 ITGB5 ENSNLEP00000046123 ENSNLEP00000046123 ITGA9 ITGA9 FBN1 FBN1 ACTN1 ACTN1 COL4A3 COL4A3 ITGB1BP1 ITGB1BP1 MUC2 MUC2 CIB2 CIB2 SRC SRC CDH17 CDH17 LCP1 LCP1 ITGA2B ITGA2B PRKCA PRKCA CASR CASR SYK SYK MADCAM1 MADCAM1 ESM1 ESM1 LOC100584814 LOC100584814 LYN LYN ITGB1BP2 ITGB1BP2 ITGB4 ITGB4 JAM2 JAM2 ITGB2 ITGB2 EMILIN1 EMILIN1 ADAMTS5 ADAMTS5 CX3CL1 CX3CL1 LGALS8 LGALS8 NF2 NF2 VWF VWF CD9 CD9 ACTN2 ACTN2 PPIA PPIA TSPAN8 TSPAN8 LGALS12 LGALS12 FERMT3 FERMT3 CCN3 CCN3 ADAM11 ADAM11 SFRP2 SFRP2 COMP COMP ITGA4 ITGA4 COL3A1 COL3A1 CCN5 CCN5 LAMA3 LAMA3 FN1 FN1 JAML JAML ADAMTS8 ADAMTS8 ICAM5 ICAM5 ITGBL1 ITGBL1 HSPG2 HSPG2 TGFBI TGFBI LAMB1 LAMB1 CD151 CD151 S1PR3 S1PR3 TSPAN4 TSPAN4 ITGA3 ITGA3 CD226 CD226 EGFL6 EGFL6 DMP1 DMP1 IBSP IBSP SPP1 SPP1 FGF1 FGF1 CCN1 CCN1 ITGA1 ITGA1 MFGE8 MFGE8 VCAM1 VCAM1 PTPRZ1 PTPRZ1 ICAM1 ICAM1 ITGA8 ITGA8 ADAM2 ADAM2 THBS4 THBS4 CALR CALR ADAMTS13 ADAMTS13 ITGA11 ITGA11 ADAM17 ADAM17 LTBP4 LTBP4 SEMA7A SEMA7A MYH9 MYH9 CCN2 CCN2 GPNMB GPNMB ANGPTL3 ANGPTL3 ADAM22 ADAM22 ICAM2 ICAM2 UTRN UTRN TNN TNN ITGAL ITGAL ITGAM ITGAM ITGAX ITGAX ITGAD ITGAD ECM2 ECM2 ANXA7 ANXA7 ITGB8 ITGB8 ITGAE ITGAE ITGA7 ITGA7 ITGA5 ITGA5 ITGB7 ITGB7 F11R F11R LOC100588496 LOC100588496 TSPAN9 TSPAN9 ENSNLEP00000025390 ENSNLEP00000025390 ENSNLEP00000025749 ENSNLEP00000025749 ADAM10 ADAM10 ITGB6 ITGB6 PTN PTN CD177 CD177 ADAM9 ADAM9 ENSNLEP00000029941 ENSNLEP00000029941 IGF2 IGF2 ICAM4 ICAM4 ADAM23 ADAM23 ADAM15 ADAM15 JAM3 JAM3 ITGB3 ITGB3 NISCH NISCH FAP FAP ENSNLEP00000032876 ENSNLEP00000032876
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
COL16A1LAM_G_DOMAIN domain-containing protein. (1472 aa)
DMDDystrophin. (3685 aa)
TLN1Talin 1. (2542 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1099 aa)
CCN4Cellular communication network factor 4. (318 aa)
ICAM3Uncharacterized protein. (446 aa)
FERMT2Fermitin family member 2. (693 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1008 aa)
P4HBProtein disulfide-isomerase. (518 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (287 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (922 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1167 aa)
CD81Tetraspanin. (274 aa)
FRMD5FERM domain containing 5. (568 aa)
ENSNLEP00000040637Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
PLPP3acidPPc domain-containing protein. (289 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (716 aa)
THY1Ig-like domain-containing protein. (216 aa)
ENSNLEP00000041273Uncharacterized protein. (190 aa)
FBLN5Fibulin 5. (470 aa)
LAMA5Laminin subunit alpha 5. (3418 aa)
ENSNLEP00000042160Tyrosine-protein phosphatase non-receptor type. (386 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1181 aa)
GFRA1GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. (467 aa)
THBS1Thrombospondin 1. (1173 aa)
ENSNLEP00000044084Fibrillar collagen NC1 domain-containing protein. (1527 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1367 aa)
ENSNLEP00000044243IGv domain-containing protein. (199 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (415 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
IGF1IlGF domain-containing protein. (196 aa)
DSTUncharacterized protein. (7409 aa)
NRG1Neuregulin 1. (713 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (859 aa)
ENSNLEP00000046123Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (136 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1035 aa)
FBN1Fibrillin 1. (2873 aa)
ACTN1Actinin alpha 1. (921 aa)
COL4A3Collagen type IV alpha 3 chain. (1600 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
MUC2Uncharacterized protein. (1539 aa)
CIB2Calcium and integrin binding family member 2. (187 aa)
SRCTyrosine-protein kinase. (537 aa)
CDH17Cadherin 17. (832 aa)
LCP1Lymphocyte cytosolic protein 1. (630 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1040 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
CASRCalcium sensing receptor. (1088 aa)
SYKTyrosine-protein kinase. (532 aa)
MADCAM1Mucosal vascular addressin cell adhesion molecule 1. (398 aa)
ESM1Endothelial cell specific molecule 1. (184 aa)
LOC100584814C-type lectin domain-containing protein. (190 aa)
LYNTyrosine-protein kinase. (512 aa)
ITGB1BP2Integrin subunit beta 1 binding protein 2. (349 aa)
ITGB4Integrin beta. (1746 aa)
JAM2Junctional adhesion molecule 2. (312 aa)
ITGB2Integrin beta. (762 aa)
EMILIN1Elastin microfibril interfacer 1. (1016 aa)
ADAMTS5ADAM metallopeptidase with thrombospondin type 1 motif 5. (932 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (397 aa)
LGALS8Galectin. (359 aa)
NF2Neurofibromin 2. (595 aa)
VWFVon Willebrand factor. (2790 aa)
CD9Tetraspanin. (228 aa)
ACTN2Actinin alpha 2. (854 aa)
PPIAPeptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (165 aa)
TSPAN8Tetraspanin. (237 aa)
LGALS12Galectin. (337 aa)
FERMT3B41 domain-containing protein. (449 aa)
CCN3Cellular communication network factor 3. (357 aa)
ADAM11ADAM metallopeptidase domain 11. (682 aa)
SFRP2Secreted frizzled related protein 2. (280 aa)
COMPTSP C-terminal domain-containing protein. (194 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
CCN5Cellular communication network factor 5. (250 aa)
LAMA3Laminin subunit alpha 3. (3316 aa)
FN1Fibronectin 1. (2477 aa)
JAMLJunction adhesion molecule like. (394 aa)
ADAMTS8Peptidase M12B domain-containing protein. (639 aa)
ICAM5Uncharacterized protein. (562 aa)
ITGBL1Integrin subunit beta like 1. (494 aa)
HSPG2Heparan sulfate proteoglycan 2. (4123 aa)
TGFBITransforming growth factor beta induced. (683 aa)
LAMB1Laminin subunit beta 1. (1810 aa)
CD151Tetraspanin. (249 aa)
S1PR3Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (378 aa)
TSPAN4Tetraspanin 4; Belongs to the tetraspanin (TM4SF) family. (213 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1050 aa)
CD226CD226 molecule. (335 aa)
EGFL6EGF like domain multiple 6. (554 aa)
DMP1Dentin matrix acidic phosphoprotein 1. (513 aa)
IBSPIntegrin binding sialoprotein. (317 aa)
SPP1Secreted phosphoprotein 1. (314 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
CCN1Cellular communication network factor 1. (317 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
MFGE8Milk fat globule-EGF factor 8 protein. (374 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
PTPRZ1Protein tyrosine phosphatase receptor type Z1. (2315 aa)
ICAM1Intercellular adhesion molecule 1. (531 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1048 aa)
ADAM2ADAM metallopeptidase domain 2. (735 aa)
THBS4Thrombospondin 4. (925 aa)
CALRCalreticulin. (417 aa)
ADAMTS13ADAM metallopeptidase with thrombospondin type 1 motif 13. (1359 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1188 aa)
ADAM17ADAM metallopeptidase domain 17. (824 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1574 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (664 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1975 aa)
CCN2Cellular communication network factor 2. (349 aa)
GPNMBGlycoprotein nmb. (575 aa)
ANGPTL3Angiopoietin like 3. (459 aa)
ADAM22ADAM metallopeptidase domain 22. (906 aa)
ICAM2Intercellular adhesion molecule 2. (275 aa)
UTRNUtrophin. (3434 aa)
TNNTenascin N. (1299 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1142 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (992 aa)
ITGAXIntegrin subunit alpha X; Belongs to the integrin alpha chain family. (1153 aa)
ITGADIntegrin subunit alpha D; Belongs to the integrin alpha chain family. (994 aa)
ECM2Extracellular matrix protein 2. (700 aa)
ANXA7Annexin. (488 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (725 aa)
ITGAEIntegrin subunit alpha E; Belongs to the integrin alpha chain family. (1164 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1023 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1038 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (799 aa)
F11RF11 receptor. (299 aa)
LOC100588496FERM domain-containing protein. (263 aa)
TSPAN9Tetraspanin. (330 aa)
ENSNLEP00000025390Tyrosine-protein phosphatase non-receptor type. (391 aa)
ENSNLEP00000025749Uncharacterized protein. (150 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
PTNPleiotrophin. (172 aa)
CD177Uncharacterized protein. (140 aa)
ADAM9ADAM metallopeptidase domain 9. (819 aa)
ENSNLEP00000029941Uncharacterized protein. (4038 aa)
IGF2IlGF domain-containing protein. (180 aa)
ICAM4ICAM_N domain-containing protein. (271 aa)
ADAM23ADAM metallopeptidase domain 23. (832 aa)
ADAM15Uncharacterized protein. (670 aa)
JAM3Junctional adhesion molecule 3. (275 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (806 aa)
NISCHNischarin. (1491 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa)
ENSNLEP00000032876Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (133 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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