STRINGSTRING
LOC100582356 LOC100582356 SPX SPX ENSNLEP00000035372 ENSNLEP00000035372 METRN METRN C1QTNF12 C1QTNF12 STC2 STC2 ADM2 ADM2 EDN1 EDN1 KL KL RETN RETN POMC POMC PENK PENK CALCA CALCA PRL PRL GCG GCG GIP GIP FNDC5 FNDC5 INHBA INHBA UCN UCN FNDC4 FNDC4 LOC100579700 LOC100579700 LOC100580921 LOC100580921 GHRL GHRL CARTPT CARTPT AGRP AGRP IAPP IAPP LOC105740367 LOC105740367 TSHB TSHB INS-IGF2 INS-IGF2 TRH TRH NTS NTS GPHA2 GPHA2 PTHLH PTHLH PYY PYY CCK CCK GHRH GHRH PMCH PMCH ENSNLEP00000037382 ENSNLEP00000037382 FBN2 FBN2 ENHO ENHO EDN3 EDN3 ENSNLEP00000043327 ENSNLEP00000043327 IGF1 IGF1 FBN1 FBN1 LOC100581058 LOC100581058 NPPB NPPB BMP10 BMP10 ECRG4 ECRG4 GALP GALP GAST GAST PRLH PRLH ERFE ERFE NMB NMB UCN3 UCN3 HCRT HCRT EPO EPO EDN2 EDN2 GUCA2A GUCA2A LEP LEP G1RPK2_NOMLE G1RPK2_NOMLE ADCYAP1 ADCYAP1 UTS2B UTS2B OSTN OSTN SST SST ADIPOQ ADIPOQ GAL GAL THPO THPO GNRH2 GNRH2 OXT OXT AVP AVP GRP GRP MLN MLN UTS2 UTS2 INSL6 INSL6 INSL4 INSL4 RLN2 RLN2 RLN1 RLN1 INHA INHA C1QTNF9 C1QTNF9 CHGB CHGB GPHB5 GPHB5 NPPC NPPC NPY NPY INSL5 INSL5 LOC100580921-2 LOC100580921-2 VIP VIP STC1 STC1 G1S3Q0_NOMLE G1S3Q0_NOMLE INHBE INHBE INHBC INHBC TOR2A TOR2A ADM ADM NPFF NPFF PTH PTH FSHB FSHB COPA COPA LOC100585742 LOC100585742 LOC100606481 LOC100606481 CORT CORT HAMP HAMP GNRH1 GNRH1 CGA CGA ENSNLEP00000027720 ENSNLEP00000027720 CCL25 CCL25 INSL3 INSL3 LHB LHB LOC100590631 LOC100590631 IGF2 IGF2 ENSNLEP00000030707 ENSNLEP00000030707 ENSNLEP00000030727 ENSNLEP00000030727 CRH CRH CALCB CALCB ENSNLEP00000033141 ENSNLEP00000033141 TTR TTR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100582356Uncharacterized protein. (217 aa)
SPXSpexin hormone. (116 aa)
ENSNLEP00000035372TGF_BETA_2 domain-containing protein. (392 aa)
METRNUncharacterized protein. (153 aa)
C1QTNF12C1q domain-containing protein. (213 aa)
STC2Stanniocalcin 2. (302 aa)
ADM2Adrenomedullin 2. (148 aa)
EDN1Endothelin 1. (211 aa)
KLKlotho. (855 aa)
RETNResistin. (108 aa)
POMCProopiomelanocortin. (243 aa)
PENKProenkephalin. (267 aa)
CALCACalcitonin related polypeptide alpha. (141 aa)
PRLProlactin. (227 aa)
GCGGlucagon. (180 aa)
GIPGastric inhibitory polypeptide. (153 aa)
FNDC5Fibronectin type III domain containing 5. (212 aa)
INHBAInhibin subunit beta A. (426 aa)
UCNUrocortin. (124 aa)
FNDC4Fibronectin type III domain containing 4. (232 aa)
LOC100579700Uncharacterized protein. (219 aa)
LOC100580921Uncharacterized protein. (216 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
CARTPTCART prepropeptide. (116 aa)
AGRPAgouti related neuropeptide. (132 aa)
IAPPIslet amyloid polypeptide. (89 aa)
LOC105740367Cys_knot domain-containing protein. (165 aa)
TSHBThyroid stimulating hormone subunit beta. (138 aa)
INS-IGF2INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (203 aa)
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (242 aa)
NTSNeurotensin. (170 aa)
GPHA2Glycoprotein hormone subunit alpha 2. (129 aa)
PTHLHParathyroid hormone like hormone. (203 aa)
PYYPeptide YY. (97 aa)
CCKCholecystokinin. (115 aa)
GHRHGrowth hormone releasing hormone. (108 aa)
PMCHPro-melanin concentrating hormone. (165 aa)
ENSNLEP00000037382Uncharacterized protein; Belongs to the NPY family. (89 aa)
FBN2Fibrillin 2. (2858 aa)
ENHOEnergy homeostasis associated. (76 aa)
EDN3Uncharacterized protein. (211 aa)
ENSNLEP00000043327Cys_knot domain-containing protein. (135 aa)
IGF1IlGF domain-containing protein. (196 aa)
FBN1Fibrillin 1. (2873 aa)
LOC100581058Cys_knot domain-containing protein. (165 aa)
NPPBNatriuretic peptide B. (134 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
ECRG4ECRG4 augurin precursor. (148 aa)
GALPGalanin like peptide. (116 aa)
GASTGastrin. (104 aa)
PRLHProlactin releasing hormone. (87 aa)
ERFEErythroferrone. (353 aa)
NMBUncharacterized protein. (121 aa)
UCN3Urocortin 3. (161 aa)
HCRTOrexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family. (131 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
EDN2Endothelin 2. (177 aa)
GUCA2AGuanylate cyclase activator 2A. (111 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
G1RPK2_NOMLEUncharacterized protein. (153 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (176 aa)
UTS2BUrotensin 2B. (119 aa)
OSTNOsteocrin. (133 aa)
SSTSomatostatin. (116 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
GALGalanin and GMAP prepropeptide. (123 aa)
THPOThrombopoietin. (353 aa)
GNRH2Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (119 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (124 aa)
AVPArginine vasopressin; Belongs to the vasopressin/oxytocin family. (164 aa)
GRPGastrin releasing peptide. (148 aa)
MLNMotilin. (115 aa)
UTS2Urotensin 2. (139 aa)
INSL6Insulin-like peptide INSL6; May have a role in sperm development and fertilization. Belongs to the insulin family. (213 aa)
INSL4Insulin like 4. (139 aa)
RLN2Relaxin 2. (185 aa)
RLN1Relaxin 1. (185 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa)
C1QTNF9C1q domain-containing protein. (333 aa)
CHGBChromogranin B. (675 aa)
GPHB5Cys_knot domain-containing protein. (112 aa)
NPPCNatriuretic peptide C. (129 aa)
NPYNeuropeptide Y. (97 aa)
INSL5Insulin like 5. (135 aa)
LOC100580921-2Growth hormone B1. (217 aa)
VIPVasoactive intestinal peptide. (170 aa)
STC1Stanniocalcin 1. (247 aa)
G1S3Q0_NOMLEUncharacterized protein. (114 aa)
INHBEInhibin subunit beta E. (350 aa)
INHBCInhibin subunit beta C. (352 aa)
TOR2ATorsin. (321 aa)
ADMAdrenomedullin. (184 aa)
NPFFNeuropeptide FF-amide peptide precursor. (113 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
FSHBFollicle stimulating hormone beta subunit. (129 aa)
COPACoatomer protein complex subunit alpha. (1070 aa)
LOC100585742Uncharacterized protein. (222 aa)
LOC100606481C1q domain-containing protein. (334 aa)
CORTCortistatin. (104 aa)
HAMPHepcidin antimicrobial peptide. (89 aa)
GNRH1Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (92 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (148 aa)
ENSNLEP00000027720Uncharacterized protein. (82 aa)
CCL25SCY domain-containing protein. (131 aa)
INSL3Insulin like 3. (157 aa)
LHBCys_knot domain-containing protein. (116 aa)
LOC100590631Cys_knot domain-containing protein. (179 aa)
IGF2IlGF domain-containing protein. (180 aa)
ENSNLEP00000030707Uncharacterized protein. (159 aa)
ENSNLEP00000030727Uncharacterized protein. (198 aa)
CRHCorticotropin releasing hormone. (196 aa)
CALCBCalcitonin related polypeptide beta. (127 aa)
ENSNLEP00000033141Uncharacterized protein. (339 aa)
TTRTransthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (163 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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