STRINGSTRING
CYP4F12 CYP4F12 HEPH HEPH MIOX MIOX CYP46A1 CYP46A1 CYP7A1 CYP7A1 TBXAS1 TBXAS1 MELTF MELTF KDM7A KDM7A CCDC160 CCDC160 RIOX2 RIOX2 OGFOD3 OGFOD3 OGFOD2 OGFOD2 CYGB CYGB CYP2E1 CYP2E1 KDM3A KDM3A EGLN3 EGLN3 FTH1 FTH1 TF TF CYP7B1 CYP7B1 TPH2 TPH2 CRTAP CRTAP CYP39A1 CYP39A1 P3H3 P3H3 CCNDBP1 CCNDBP1 PLOD2 PLOD2 CYP4F22 CYP4F22 CYP4F8 CYP4F8 CYP4F11 CYP4F11 ABCE1 ABCE1 CYP19A1 CYP19A1 G1R458_NOMLE G1R458_NOMLE P4HTM P4HTM P3H2 P3H2 ISCU ISCU CYP24A1 CYP24A1 ALKBH8 ALKBH8 ADI1 ADI1 LOC100583507 LOC100583507 HBQ1 HBQ1 FA2H FA2H PPEF2 PPEF2 PLOD3 PLOD3 CYP2W1 CYP2W1 SCD5 SCD5 CYP27A1 CYP27A1 ALOX12 ALOX12 PLOD1 PLOD1 ALOX12B ALOX12B ALOXE3 ALOXE3 NFU1 NFU1 CYP26B1 CYP26B1 P3H4 P3H4 CYP3A5 CYP3A5 LOC100593175 LOC100593175 G1RKH8_NOMLE G1RKH8_NOMLE LOC100602871 LOC100602871 KLKB1 KLKB1 TET1 TET1 TTI2 TTI2 PHYH PHYH ACP5 ACP5 P4HA2 P4HA2 CYP26C1 CYP26C1 CYP26A1 CYP26A1 CALR CALR LOC100592267 LOC100592267 CYP2C19 CYP2C19 G1RRE2_NOMLE G1RRE2_NOMLE PTGIS PTGIS CYP2C8 CYP2C8 CYP4X1 CYP4X1 LOC100580825 LOC100580825 TET2 TET2 CYP2S1 CYP2S1 G1RU85_NOMLE G1RU85_NOMLE CYP2A13 CYP2A13 EGLN2 EGLN2 SNCA SNCA CYP1A1 CYP1A1 CYP1A2 CYP1A2 SCD SCD HIF1AN HIF1AN CYP2J2 CYP2J2 CYP17A1 CYP17A1 ACO2 ACO2 CYP27C1 CYP27C1 LOC100606221 LOC100606221 TMLHE TMLHE ALOX5 ALOX5 CYP1B1 CYP1B1 AGMO AGMO FBXL5 FBXL5 LOC100588910 LOC100588910 FAXDC2 FAXDC2 HAAO HAAO ALKBH1 ALKBH1 CYP27B1 CYP27B1 ALOX15 ALOX15 CYP2R1 CYP2R1 TPH1 TPH1 SAAL1 SAAL1 BBOX1 BBOX1 CH25H CH25H G1SAN7_NOMLE G1SAN7_NOMLE FTMT FTMT PIGS PIGS LOC100599862 LOC100599862 ALKBH3 ALKBH3 DPH3 DPH3 PPEF1 PPEF1 LOC100582268 LOC100582268 CDO1 CDO1 DOHH DOHH PHF8 PHF8 P4HA3 P4HA3 FXN FXN ENSNLEP00000029093 ENSNLEP00000029093 CYP3A4 CYP3A4 ENSNLEP00000030218 ENSNLEP00000030218 LOC100593769 LOC100593769 AOX1 AOX1 ETHE1 ETHE1 MSMO1 MSMO1 METTL26 METTL26 CYP4F2 CYP4F2 LCN2 LCN2 LTF LTF ENSNLEP00000032560 ENSNLEP00000032560 ENSNLEP00000032785 ENSNLEP00000032785 FDX1 FDX1 ENSNLEP00000033588 ENSNLEP00000033588 ENSNLEP00000033672 ENSNLEP00000033672 ALKBH2 ALKBH2 CYP51A1 CYP51A1 LYRM4 LYRM4 P4HA1 P4HA1 CYP2B6 CYP2B6 ENSNLEP00000035742 ENSNLEP00000035742 ENSNLEP00000035804 ENSNLEP00000035804 PAH PAH LOC100583419 LOC100583419 EGLN1 EGLN1 OGFOD1 OGFOD1 ENSNLEP00000037793 ENSNLEP00000037793 TYW5 TYW5 ENSNLEP00000037971 ENSNLEP00000037971 PHF2 PHF2 RRM2 RRM2 LOC101179148 LOC101179148 EIPR1 EIPR1 JMJD6 JMJD6 CYP11B2 CYP11B2 ADO ADO FTO FTO P3H1 P3H1 LOC100580051 LOC100580051 XDH XDH RIOX1 RIOX1 SC5D SC5D LOC105740713 LOC105740713 FTL FTL LOC100598070 LOC100598070 LOC105737755 LOC105737755 DNAJC24 DNAJC24 TH TH ENSNLEP00000048874 ENSNLEP00000048874 CYP2G2 CYP2G2 ENSNLEP00000048409 ENSNLEP00000048409 ENSNLEP00000048186 ENSNLEP00000048186 ENSNLEP00000047885 ENSNLEP00000047885 LOC100579320 LOC100579320 ENSNLEP00000045560 ENSNLEP00000045560 CYP20A1 CYP20A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CYP4F12Cytochrome P450 family 4 subfamily F member 12; Belongs to the cytochrome P450 family. (458 aa)
HEPHHephaestin; Belongs to the multicopper oxidase family. (1210 aa)
MIOXMyo-inositol oxygenase. (265 aa)
CYP46A1Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (499 aa)
CYP7A1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa)
TBXAS1Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (580 aa)
MELTFMelanotransferrin; Belongs to the transferrin family. (737 aa)
KDM7ALysine demethylase 7A. (910 aa)
CCDC160Coiled-coil domain containing 160. (325 aa)
RIOX2Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (465 aa)
OGFOD32-oxoglutarate and iron dependent oxygenase domain containing 3. (331 aa)
OGFOD2Fe2OG dioxygenase domain-containing protein. (417 aa)
CYGBGLOBIN domain-containing protein; Belongs to the globin family. (205 aa)
CYP2E1Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. (531 aa)
KDM3AJmjC domain-containing protein. (1035 aa)
EGLN3Egl-9 family hypoxia inducible factor 3. (239 aa)
FTH1Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (183 aa)
TFTransferrin; Belongs to the transferrin family. (698 aa)
CYP7B1Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (506 aa)
TPH2Tryptophan hydroxylase 2. (490 aa)
CRTAPCartilage associated protein. (406 aa)
CYP39A1Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family. (469 aa)
P3H3Prolyl 3-hydroxylase 3. (738 aa)
CCNDBP1Cyclin D1 binding protein 1. (359 aa)
PLOD2Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (758 aa)
CYP4F22Cytochrome P450 family 4 subfamily F member 22; Belongs to the cytochrome P450 family. (536 aa)
CYP4F8Cytochrome P450 family 4 subfamily F member 8; Belongs to the cytochrome P450 family. (520 aa)
CYP4F11Cytochrome P450 family 4 subfamily F member 11; Belongs to the cytochrome P450 family. (524 aa)
ABCE1ATP binding cassette subfamily E member 1. (599 aa)
CYP19A1Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa)
G1R458_NOMLEUncharacterized protein; Belongs to the cytochrome P450 family. (135 aa)
P4HTMProlyl 4-hydroxylase, transmembrane. (563 aa)
P3H2Fe2OG dioxygenase domain-containing protein. (527 aa)
ISCUIron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (167 aa)
CYP24A1Cytochrome P450 family 24 subfamily A member 1; Belongs to the cytochrome P450 family. (513 aa)
ALKBH8AlkB homolog 8, tRNA methyltransferase. (664 aa)
ADI11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (179 aa)
LOC100583507GLOBIN domain-containing protein; Belongs to the globin family. (142 aa)
HBQ1Hemoglobin subunit theta 1; Belongs to the globin family. (142 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (338 aa)
PPEF2Serine/threonine-protein phosphatase with EF-hands. (757 aa)
PLOD3Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (628 aa)
CYP2W1Cytochrome P450 family 2 subfamily W member 1; Belongs to the cytochrome P450 family. (467 aa)
SCD5FA_desaturase domain-containing protein; Belongs to the fatty acid desaturase type 1 family. (257 aa)
CYP27A1Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (534 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S type. (639 aa)
PLOD1Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1. (667 aa)
ALOX12BArachidonate 12-lipoxygenase, 12R type. (620 aa)
ALOXE3Arachidonate lipoxygenase 3. (848 aa)
NFU1NFU1 iron-sulfur cluster scaffold. (230 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
P3H4Prolyl 3-hydroxylase family member 4 (non-enzymatic). (437 aa)
CYP3A5Cytochrome P450 family 3 subfamily A member 5. (502 aa)
LOC100593175Uncharacterized protein. (495 aa)
G1RKH8_NOMLEUncharacterized protein. (74 aa)
LOC100602871Uncharacterized protein. (471 aa)
KLKB1Kallikrein B1; Belongs to the peptidase S1 family. (638 aa)
TET1Tet methylcytosine dioxygenase 1. (2136 aa)
TTI2TELO2 interacting protein 2. (507 aa)
PHYHPhytanoyl-CoA 2-hydroxylase. (319 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (325 aa)
P4HA2Prolyl 4-hydroxylase subunit alpha 2. (535 aa)
CYP26C1Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (522 aa)
CYP26A1Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. (497 aa)
CALRCalreticulin. (417 aa)
LOC100592267Uncharacterized protein; Belongs to the cytochrome P450 family. (336 aa)
CYP2C19Cytochrome P450 family 2 subfamily C member 19; Belongs to the cytochrome P450 family. (490 aa)
G1RRE2_NOMLEUncharacterized protein. (443 aa)
PTGISProstacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa)
CYP2C8Cytochrome P450 family 2 subfamily C member 8; Belongs to the cytochrome P450 family. (420 aa)
CYP4X1Cytochrome P450 family 4 subfamily X member 1; Belongs to the cytochrome P450 family. (509 aa)
LOC100580825Uncharacterized protein. (420 aa)
TET2Tet methylcytosine dioxygenase 2. (2001 aa)
CYP2S1Cytochrome P450 family 2 subfamily S member 1; Belongs to the cytochrome P450 family. (503 aa)
G1RU85_NOMLEUncharacterized protein. (291 aa)
CYP2A13Cytochrome P450 family 2 subfamily A member 13; Belongs to the cytochrome P450 family. (494 aa)
EGLN2Egl-9 family hypoxia inducible factor 2. (407 aa)
SNCAAlpha-synuclein; Belongs to the synuclein family. (140 aa)
CYP1A1Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (512 aa)
CYP1A2Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. (516 aa)
SCDStearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (356 aa)
HIF1ANHypoxia inducible factor 1 subunit alpha inhibitor. (349 aa)
CYP2J2Cytochrome P450 family 2 subfamily J member 2; Belongs to the cytochrome P450 family. (502 aa)
CYP17A1Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family. (506 aa)
ACO2Aconitase 2. (800 aa)
CYP27C1Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family. (372 aa)
LOC100606221Uncharacterized protein; Belongs to the cytochrome P450 family. (485 aa)
TMLHETrimethyllysine hydroxylase, epsilon. (421 aa)
ALOX5Arachidonate 5-lipoxygenase. (655 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
AGMOAlkylglycerol monooxygenase; Belongs to the sterol desaturase family. (445 aa)
FBXL5F-box and leucine rich repeat protein 5. (691 aa)
LOC100588910Uncharacterized protein; Belongs to the cytochrome P450 family. (499 aa)
FAXDC2Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. (310 aa)
HAAO3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (286 aa)
ALKBH1AlkB homolog 1, histone H2A dioxygenase. (334 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
ALOX15Arachidonate 15-lipoxygenase. (662 aa)
CYP2R1Cytochrome P450 family 2 subfamily R member 1; Belongs to the cytochrome P450 family. (501 aa)
TPH1Tryptophan hydroxylase 1. (444 aa)
SAAL1Serum amyloid A like 1. (431 aa)
BBOX1Gamma-butyrobetaine hydroxylase 1. (387 aa)
CH25HCholesterol 25-hydroxylase; Belongs to the sterol desaturase family. (272 aa)
G1SAN7_NOMLEUncharacterized protein. (51 aa)
FTMTFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (242 aa)
PIGSPhosphatidylinositol glycan anchor biosynthesis class S. (554 aa)
LOC100599862Uncharacterized protein. (610 aa)
ALKBH3AlkB homolog 3, alpha-ketoglutaratedependent dioxygenase. (286 aa)
DPH3Diphthamide biosynthesis 3. (82 aa)
PPEF1Serine/threonine-protein phosphatase with EF-hands. (651 aa)
LOC100582268Uncharacterized protein; Belongs to the cytochrome P450 family. (502 aa)
CDO1Cysteine dioxygenase. (200 aa)
DOHHUncharacterized protein. (252 aa)
PHF8PHD finger protein 8. (1060 aa)
P4HA3Prolyl 4-hydroxylase subunit alpha 3. (548 aa)
FXNUncharacterized protein. (196 aa)
ENSNLEP00000029093annotation not available (61 aa)
CYP3A4Cytochrome P450 family 3 subfamily A member 4. (503 aa)
ENSNLEP00000030218Uncharacterized protein. (112 aa)
LOC100593769Uncharacterized protein; Belongs to the cytochrome P450 family. (385 aa)
AOX1Aldehyde oxidase 1. (1338 aa)
ETHE1ETHE1 persulfide dioxygenase. (260 aa)
MSMO1Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. (293 aa)
METTL26Methyltransferase like 26. (205 aa)
CYP4F2Cytochrome P450 family 4 subfamily F member 2; Belongs to the cytochrome P450 family. (519 aa)
LCN2Lipocalin 2; Belongs to the calycin superfamily. Lipocalin family. (191 aa)
LTFUncharacterized protein. (453 aa)
ENSNLEP00000032560Nfu_N domain-containing protein. (232 aa)
ENSNLEP00000032785Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (165 aa)
FDX1Ferredoxin 1. (184 aa)
ENSNLEP00000033588Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (178 aa)
ENSNLEP00000033672Uncharacterized protein; Belongs to the cytochrome P450 family. (410 aa)
ALKBH2AlkB homolog 2, alpha-ketoglutarate dependent dioxygenase. (261 aa)
CYP51A1Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family. (509 aa)
LYRM4LYR motif containing 4; Belongs to the complex I LYR family. (130 aa)
P4HA1Prolyl 4-hydroxylase subunit alpha 1. (485 aa)
CYP2B6Cytochrome P450 family 2 subfamily B member 6. (447 aa)
ENSNLEP00000035742ABC transporter domain-containing protein. (189 aa)
ENSNLEP00000035804Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (92 aa)
PAHPhenylalanine hydroxylase. (459 aa)
LOC100583419FAD-binding PCMH-type domain-containing protein. (1085 aa)
EGLN1Egl-9 family hypoxia inducible factor 1. (416 aa)
OGFOD12-oxoglutarate and iron dependent oxygenase domain containing 1. (542 aa)
ENSNLEP00000037793Uncharacterized protein. (122 aa)
TYW5tRNA-yW synthesizing protein 5. (315 aa)
ENSNLEP00000037971Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (145 aa)
PHF2Uncharacterized protein. (300 aa)
RRM2Ribonucleotide reductase regulatory subunit M2. (448 aa)
LOC101179148Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (183 aa)
EIPR1EARP complex and GARP complex interacting protein 1. (394 aa)
JMJD6JmjC domain-containing protein. (249 aa)
CYP11B2Cytochrome P450 family 11 subfamily B member 2; Belongs to the cytochrome P450 family. (566 aa)
ADOUncharacterized protein. (216 aa)
FTOFTO alpha-ketoglutarate dependent dioxygenase. (559 aa)
P3H1Fe2OG dioxygenase domain-containing protein. (621 aa)
LOC100580051Uncharacterized protein; Belongs to the cytochrome P450 family. (458 aa)
XDHXanthine dehydrogenase. (1271 aa)
RIOX1Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (622 aa)
SC5DSterol-C5-desaturase; Belongs to the sterol desaturase family. (299 aa)
LOC1057407132Fe-2S ferredoxin-type domain-containing protein. (172 aa)
FTLFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (184 aa)
LOC100598070Uncharacterized protein. (503 aa)
LOC105737755Uncharacterized protein; Belongs to the cytochrome P450 family. (440 aa)
DNAJC24DnaJ heat shock protein family (Hsp40) member C24. (149 aa)
THTyrosine hydroxylase. (507 aa)
ENSNLEP00000048874Uncharacterized protein. (178 aa)
CYP2G2Uncharacterized protein. (515 aa)
ENSNLEP00000048409Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (183 aa)
ENSNLEP00000048186Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (466 aa)
ENSNLEP00000047885Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (180 aa)
LOC100579320Uncharacterized protein; Belongs to the cytochrome P450 family. (520 aa)
ENSNLEP00000045560Uncharacterized protein. (723 aa)
CYP20A1Cytochrome P450 family 20 subfamily A member 1. (470 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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