STRINGSTRING
URAD URAD XDH XDH GMPR2 GMPR2 ENSNLEP00000038989 ENSNLEP00000038989 LOC100597726 LOC100597726 PAICS PAICS GMPR GMPR KDM1A KDM1A HPRT1 HPRT1 DPYSL5 DPYSL5 ACPP ACPP ADK ADK GDA GDA ENSNLEP00000029534 ENSNLEP00000029534 ADA ADA GART GART PPAT PPAT DPYD DPYD SHMT1 SHMT1 APRT APRT SHMT2 SHMT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
URADUreidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase. (154 aa)
XDHXanthine dehydrogenase. (1271 aa)
GMPR2GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (395 aa)
ENSNLEP00000038989Uncharacterized protein. (64 aa)
LOC100597726Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family. (261 aa)
PAICSAIRC domain-containing protein. (451 aa)
GMPRGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (345 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (759 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
DPYSL5Dihydropyrimidinase like 5. (564 aa)
ACPPAcid phosphatase, prostate; Belongs to the histidine acid phosphatase family. (418 aa)
ADKAdenosine kinase. (362 aa)
GDAGuanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (471 aa)
ENSNLEP00000029534AIRC domain-containing protein. (373 aa)
ADAAdenosine deaminase. (405 aa)
GARTTrifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1010 aa)
PPATAmidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (545 aa)
DPYDDihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1025 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (427 aa)
APRTAdenine phosphoribosyltransferase. (180 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (531 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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