STRINGSTRING
STON1 STON1 E2F2 E2F2 TAF11 TAF11 MED15 MED15 LOC100581166 LOC100581166 TAF12 TAF12 GTF2A1 GTF2A1 POLR2G POLR2G ENSNLEP00000033138 ENSNLEP00000033138 GTF2H5 GTF2H5 MED31 MED31 MED16 MED16 ELOB-2 ELOB-2 ENSNLEP00000028300 ENSNLEP00000028300 ENSNLEP00000027740 ENSNLEP00000027740 TAF6L TAF6L MAZ MAZ TAF7L TAF7L TAF4B TAF4B MED26 MED26 TAF1L TAF1L GTF2E1 GTF2E1 MED30 MED30 TAF8 TAF8 MED7 MED7 MED4 MED4 MED21 MED21 MED20 MED20 POLR2D POLR2D TAF2 TAF2 ENSNLEP00000040328 ENSNLEP00000040328 LOC100585732 LOC100585732 CDK7 CDK7 ENSNLEP00000035860 ENSNLEP00000035860 ENSNLEP00000035510 ENSNLEP00000035510 ENSNLEP00000035465 ENSNLEP00000035465 MED24 MED24 TBP TBP TAF1 TAF1 TAF13 TAF13 GTF2F2 GTF2F2 LOC100604447 LOC100604447 MED14 MED14 CDK9 CDK9 TAF10 TAF10 MED28 MED28 LOC100592975 LOC100592975 GTF2F1 GTF2F1 TAF4 TAF4 ERCC3 ERCC3 TAF5 TAF5 MED23 MED23 MED29 MED29 MED8 MED8 LOC100595123 LOC100595123 ENSNLEP00000042108 ENSNLEP00000042108 CCNH CCNH GTF2A2 GTF2A2 MED9 MED9 MED22 MED22 MED19 MED19 MED27 MED27 TAF3 TAF3 GTF2E2 GTF2E2 ENSNLEP00000041823 ENSNLEP00000041823 PPARGC1A PPARGC1A E2F3 E2F3 ENSNLEP00000040842 ENSNLEP00000040842 ELOA ELOA POLR2I POLR2I TAF6 TAF6 LOC105739614 LOC105739614 DR1 DR1 GTF2B GTF2B MED18 MED18 ELOB ELOB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STON1Stonin-1; May be involved in the endocytic machinery. (1182 aa)
E2F2E2F transcription factor 2. (437 aa)
TAF11TATA-box binding protein associated factor 11. (211 aa)
MED15Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (786 aa)
LOC100581166Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
TAF12TFIID_20kDa domain-containing protein. (213 aa)
GTF2A1General transcription factor IIA subunit 1. (376 aa)
POLR2GS1 domain-containing protein. (189 aa)
ENSNLEP00000033138Protein kinase domain-containing protein. (310 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
MED31Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (131 aa)
MED16Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (822 aa)
ELOB-2Ubiquitin-like domain-containing protein. (142 aa)
ENSNLEP00000028300TFIIA_gamma_N domain-containing protein. (56 aa)
ENSNLEP00000027740Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (91 aa)
TAF6LTATA-box binding protein associated factor 6 like. (601 aa)
MAZUncharacterized protein. (400 aa)
TAF7LTAFII55_N domain-containing protein. (424 aa)
TAF4BTATA-box binding protein associated factor 4b. (867 aa)
MED26TFIIS N-terminal domain-containing protein. (590 aa)
TAF1LTATA-box binding protein associated factor 1 like. (1779 aa)
GTF2E1General transcription factor IIE subunit 1. (439 aa)
MED30Mediator complex subunit 30. (178 aa)
TAF8TATA-box binding protein associated factor 8. (338 aa)
MED7Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (233 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (270 aa)
MED21Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (159 aa)
MED20Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (212 aa)
POLR2DRNA polymerase II subunit D. (154 aa)
TAF2TATA-box binding protein associated factor 2. (1199 aa)
ENSNLEP00000040328Uncharacterized protein. (192 aa)
LOC100585732TFIIS N-terminal domain-containing protein. (547 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (341 aa)
ENSNLEP00000035860TAFII28 domain-containing protein. (179 aa)
ENSNLEP00000035510Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
ENSNLEP00000035465Uncharacterized protein. (86 aa)
MED24Mediator complex subunit 24. (1003 aa)
TBPTATA-box binding protein. (328 aa)
TAF1TATA-box binding protein associated factor 1. (1767 aa)
TAF13TATA-box binding protein associated factor 13. (124 aa)
GTF2F2General transcription factor IIF subunit 2. (239 aa)
LOC100604447Ubiquitin-like domain-containing protein. (118 aa)
MED14Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1454 aa)
CDK9Cyclin dependent kinase 9. (372 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
MED28Uncharacterized protein. (223 aa)
LOC100592975Uncharacterized protein. (311 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (511 aa)
TAF4TATA-box binding protein associated factor 4. (905 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (737 aa)
TAF5TATA-box binding protein associated factor 5. (800 aa)
MED23Mediator complex subunit 23. (1368 aa)
MED29Mediator complex subunit 29. (221 aa)
MED8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (313 aa)
LOC100595123Uncharacterized protein. (262 aa)
ENSNLEP00000042108Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (82 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
MED9Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (146 aa)
MED22Mediator complex subunit 22. (200 aa)
MED19Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (261 aa)
MED27Mediator complex subunit 27. (311 aa)
TAF3PHD-type domain-containing protein. (768 aa)
GTF2E2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (291 aa)
ENSNLEP00000041823TAFII28 domain-containing protein. (197 aa)
PPARGC1APPARG coactivator 1 alpha. (801 aa)
E2F3E2F transcription factor 3. (397 aa)
ENSNLEP00000040842Uncharacterized protein. (492 aa)
ELOAElongin A. (747 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
TAF6TATA-box binding protein associated factor 6. (649 aa)
LOC105739614TFIIS N-terminal domain-containing protein. (537 aa)
DR1Down-regulator of transcription 1. (176 aa)
GTF2BGeneral transcription factor IIB. (316 aa)
MED18Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (208 aa)
ELOBElongin B. (157 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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