STRINGSTRING
SYNJ1 SYNJ1 DDC DDC GABRA2 GABRA2 PSEN1 PSEN1 DRD2 DRD2 ENSNLEP00000029188 ENSNLEP00000029188 SLC6A9 SLC6A9 ERC2 ERC2 NT5DC2 NT5DC2 RIMS4 RIMS4 NT5DC3 NT5DC3 SLC32A1 SLC32A1 SYT12 SYT12 SLC29A2 SLC29A2 SLC17A8 SLC17A8 RAB3A RAB3A BLOC1S6 BLOC1S6 SLC28A2 SLC28A2 NLGN1 NLGN1 SEPTIN5 SEPTIN5 SLC6A15 SLC6A15 SLC17A7 SLC17A7 NRXN2 NRXN2 SLC6A16 SLC6A16 SYT1 SYT1 LIN7B LIN7B SYN3 SYN3 STX3 STX3 SYN2 SYN2 SLC6A11 SLC6A11 CDK5 CDK5 RAP1A RAP1A RIMS2 RIMS2 SLC29A1 SLC29A1 SLC6A4 SLC6A4 SLC6A17 SLC6A17 OTOF OTOF BRAF BRAF SCRIB SCRIB STXBP3 STXBP3 SLC6A12 SLC6A12 STXBP2 STXBP2 CTBP2 CTBP2 CPLX2 CPLX2 RPH3AL RPH3AL SLC6A8 SLC6A8 RPH3A RPH3A LIN7A LIN7A SLC6A2 SLC6A2 PPFIA3 PPFIA3 SLC18A1 SLC18A1 SNAPIN SNAPIN ICA1 ICA1 PRRT2 PRRT2 LOC100581641 LOC100581641 PDZD11 PDZD11 SLC6A6 SLC6A6 SLC1A6 SLC1A6 SYN1 SYN1 SLC17A6 SLC17A6 SLC6A5 SLC6A5 NR4A1 NR4A1 SYT9 SYT9 NRXN3 NRXN3 SLC18A2 SLC18A2 STX4 STX4 P2RX7 P2RX7 CHAT CHAT HRH3 HRH3 STX11 STX11 SNAP25 SNAP25 SNCA SNCA SNAP47 SNAP47 GABRQ GABRQ SYT8 SYT8 SV2B SV2B RIMS3 RIMS3 PPT1 PPT1 CADPS2 CADPS2 CADPS CADPS PRKN PRKN SLC22A3 SLC22A3 SLC22A2 SLC22A2 SLC6A3 SLC6A3 SLC6A18 SLC6A18 SLC5A7 SLC5A7 SYT4 SYT4 BRSK1 BRSK1 SV2A SV2A CPLX4 CPLX4 STX2 STX2 DOC2A DOC2A GRM4 GRM4 SLC6A13 SLC6A13 ATP1A2 ATP1A2 SYT2 SYT2 DGKI DGKI SLC6A7 SLC6A7 SLC1A7 SLC1A7 LRRC1 LRRC1 PIP5K1C PIP5K1C UNC13A UNC13A SLC1A1 SLC1A1 TH TH ENSNLEP00000044067 ENSNLEP00000044067 SLC1A3 SLC1A3 PARK7 PARK7 CPLX3 CPLX3 SLC22A1 SLC22A1 SYT5 SYT5 PTPRN2 PTPRN2 DVL1 DVL1 PCLO PCLO ASIC1 ASIC1 NF1 NF1 RIMS1 RIMS1 UNC13B UNC13B NRXN1 NRXN1 SYT7 SYT7 UNC13C UNC13C SLC1A2 SLC1A2 ENSNLEP00000036861 ENSNLEP00000036861 ENSNLEP00000036455 ENSNLEP00000036455 SV2C SV2C SNAP23 SNAP23 STX1B STX1B CLN8 CLN8 ENSNLEP00000034296 ENSNLEP00000034296 DNAJC5 DNAJC5 STX1A STX1A LIN7C LIN7C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SYNJ1Synaptojanin 1. (1383 aa)
DDCDopa decarboxylase. (489 aa)
GABRA2Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (511 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (445 aa)
ENSNLEP00000029188Uncharacterized protein. (60 aa)
SLC6A9Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (649 aa)
ERC2ELKS/RAB6-interacting/CAST family member 2. (957 aa)
NT5DC25'-nucleotidase domain containing 2. (558 aa)
RIMS4Regulating synaptic membrane exocytosis 4. (216 aa)
NT5DC35'-nucleotidase domain containing 3. (548 aa)
SLC32A1Solute carrier family 32 member 1. (427 aa)
SYT12Synaptotagmin 12. (421 aa)
SLC29A2Solute carrier family 29 member 2. (371 aa)
SLC17A8Solute carrier family 17 member 8. (589 aa)
RAB3ARAB3A, member RAS oncogene family. (186 aa)
BLOC1S6Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (176 aa)
SLC28A2Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (658 aa)
NLGN1Neuroligin 1. (823 aa)
SEPTIN5Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (323 aa)
SLC6A15Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (730 aa)
SLC17A7Solute carrier family 17 member 7. (557 aa)
NRXN2Neurexin 2. (1626 aa)
SLC6A16Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (736 aa)
SYT1Synaptotagmin 1. (422 aa)
LIN7BProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (207 aa)
SYN3Synapsin III. (580 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (251 aa)
SYN2Uncharacterized protein. (506 aa)
SLC6A11Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (623 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
RIMS2Uncharacterized protein. (1367 aa)
SLC29A1Solute carrier family 29 member 1 (Augustine blood group). (485 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (625 aa)
SLC6A17Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (727 aa)
OTOFOtoferlin. (1968 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (764 aa)
SCRIBScribble planar cell polarity protein. (1449 aa)
STXBP3Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (592 aa)
SLC6A12Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (576 aa)
STXBP2Syntaxin binding protein 2; Belongs to the STXBP/unc-18/SEC1 family. (579 aa)
CTBP2C-terminal binding protein 2. (957 aa)
CPLX2Complexin 2. (134 aa)
RPH3ALRabphilin 3A like (without C2 domains). (314 aa)
SLC6A8Solute carrier family 6 member 8. (547 aa)
RPH3ARabphilin 3A. (693 aa)
LIN7AProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (233 aa)
SLC6A2Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (628 aa)
PPFIA3PTPRF interacting protein alpha 3. (1151 aa)
SLC18A1Solute carrier family 18 member A1. (525 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
ICA1Islet cell autoantigen 1. (512 aa)
PRRT2Proline rich transmembrane protein 2. (349 aa)
LOC100581641Uncharacterized protein. (352 aa)
PDZD11PDZ domain containing 11. (140 aa)
SLC6A6Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (620 aa)
SLC1A6Amino acid transporter. (441 aa)
SYN1Synapsin I. (639 aa)
SLC17A6Solute carrier family 17 member 6. (582 aa)
SLC6A5Solute carrier family 6 member 5. (793 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (589 aa)
SYT9Synaptotagmin 9. (472 aa)
NRXN3Uncharacterized protein. (1061 aa)
SLC18A2Solute carrier family 18 member A2. (514 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (297 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
CHATCholine O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (631 aa)
HRH3Histamine receptor H3; Belongs to the G-protein coupled receptor 1 family. (445 aa)
STX11Syntaxin 11; Belongs to the syntaxin family. (287 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
SNCAAlpha-synuclein; Belongs to the synuclein family. (140 aa)
SNAP47Synaptosome associated protein 47. (464 aa)
GABRQGamma-aminobutyric acid type A receptor theta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (631 aa)
SYT8Synaptotagmin 8. (400 aa)
SV2BSynaptic vesicle glycoprotein 2B. (683 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (308 aa)
PPT1Palmitoyl-protein thioesterase 1. (326 aa)
CADPS2Calcium dependent secretion activator 2. (1297 aa)
CADPSUncharacterized protein. (1183 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (437 aa)
SLC22A3MFS domain-containing protein. (368 aa)
SLC22A2Solute carrier family 22 member 2. (521 aa)
SLC6A3Solute carrier family 6 member 3. (552 aa)
SLC6A18Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (589 aa)
SLC5A7Solute carrier family 5 member 7; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (580 aa)
SYT4Synaptotagmin 4. (425 aa)
BRSK1UBA domain-containing protein. (449 aa)
SV2ASynaptic vesicle glycoprotein 2A. (742 aa)
CPLX4Complexin 4. (160 aa)
STX2Syntaxin 2; Belongs to the syntaxin family. (287 aa)
DOC2ADouble C2 domain alpha. (355 aa)
GRM4Glutamate metabotropic receptor 4. (888 aa)
SLC6A13Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (515 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
SYT2Synaptotagmin 2. (419 aa)
DGKIDiacylglycerol kinase. (1026 aa)
SLC6A7Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (668 aa)
SLC1A7Amino acid transporter. (619 aa)
LRRC1Leucine rich repeat containing 1. (503 aa)
PIP5K1CPIPK domain-containing protein. (759 aa)
UNC13AUnc-13 homolog A. (1460 aa)
SLC1A1Amino acid transporter. (457 aa)
THTyrosine hydroxylase. (507 aa)
ENSNLEP00000044067Uncharacterized protein. (108 aa)
SLC1A3Amino acid transporter. (542 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
CPLX3Complexin 3. (158 aa)
SLC22A1Uncharacterized protein. (142 aa)
SYT5C2 domain-containing protein. (235 aa)
PTPRN2Protein tyrosine phosphatase receptor type N2. (1015 aa)
DVL1Dishevelled segment polarity protein 1. (667 aa)
PCLOUncharacterized protein. (1217 aa)
ASIC1Acid sensing ion channel subunit 1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (479 aa)
NF1Neurofibromin 1. (2839 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1637 aa)
UNC13BUncharacterized protein. (4218 aa)
NRXN1Neurexin 1. (1547 aa)
SYT7Uncharacterized protein. (592 aa)
UNC13CC2 domain-containing protein. (135 aa)
SLC1A2Amino acid transporter. (580 aa)
ENSNLEP00000036861Uncharacterized protein. (119 aa)
ENSNLEP00000036455Uncharacterized protein. (127 aa)
SV2CSynaptic vesicle glycoprotein 2C. (666 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
STX1BSyntaxin 1B; Belongs to the syntaxin family. (293 aa)
CLN8CLN8 transmembrane ER and ERGIC protein. (286 aa)
ENSNLEP00000034296DJ-1_PfpI domain-containing protein. (133 aa)
DNAJC5DnaJ heat shock protein family (Hsp40) member C5. (198 aa)
STX1At-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (243 aa)
LIN7CProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (197 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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