STRINGSTRING
CRKL CRKL PRKCZ PRKCZ HTT HTT KIF25 KIF25 CDX2 CDX2 MSN MSN OPHN1 OPHN1 CRK CRK BCCIP BCCIP MISP MISP CAMSAP3 CAMSAP3 CYTH3 CYTH3 OOEP OOEP STK11 STK11 RAB10 RAB10 SYNJ2BP SYNJ2BP FBF1 FBF1 SCRIB SCRIB GPSM2 GPSM2 FRMD4B FRMD4B SPAG5 SPAG5 RSKR RSKR ARHGAP35 ARHGAP35 ERBIN ERBIN EPHB1 EPHB1 NEK3 NEK3 KIF26B KIF26B PTK7 PTK7 CARMIL2 CARMIL2 CCL21 CCL21 PDCD6IP PDCD6IP PARD6A PARD6A G1QYG1_NOMLE G1QYG1_NOMLE LIN7B LIN7B DOCK2 DOCK2 FAM89B FAM89B NT5DC3 NT5DC3 TCIRG1 TCIRG1 RHOA RHOA NDC80 NDC80 LAMA1 LAMA1 MTCL1 MTCL1 PARD6B PARD6B PARD3B PARD3B NT5DC2 NT5DC2 WNT5A WNT5A CD3G CD3G CRTAM CRTAM FEZ1 FEZ1 ANKFN1 ANKFN1 ALPK2 ALPK2 PARD6G PARD6G SAPCD2 SAPCD2 MAD2L1 MAD2L1 LRRC7 LRRC7 TCF15 TCF15 SLC9A1 SLC9A1 MAPRE1 MAPRE1 TMEM114 TMEM114 CYP26B1 CYP26B1 SLC9A3R1 SLC9A3R1 BRSK1 BRSK1 DLG5 DLG5 DYNLT1 DYNLT1 FOXF1 FOXF1 FAT1 FAT1 SYNE4 SYNE4 ACTR3 ACTR3 RND2 RND2 PLK1 PLK1 RHOBTB1 RHOBTB1 FRMD4A FRMD4A FSCN3 FSCN3 ANK1 ANK1 FAM193B FAM193B ARHGEF11 ARHGEF11 TRAF3IP2 TRAF3IP2 PDLIM1 PDLIM1 BRSK2 BRSK2 WNT7B WNT7B MYO9A MYO9A STK25 STK25 RHOJ RHOJ FERMT1 FERMT1 TMEM53 TMEM53 RHOBTB3 RHOBTB3 G1RVW8_NOMLE G1RVW8_NOMLE MYH9 MYH9 AMOT AMOT MAP7 MAP7 PATJ PATJ MCPH1 MCPH1 DOCK7 DOCK7 GBF1 GBF1 UST UST ACTR3B ACTR3B RAC1 RAC1 PARVG PARVG G1S1M4_NOMLE G1S1M4_NOMLE WDR1 WDR1 WNT11 WNT11 SIPA1L3 SIPA1L3 CDK5RAP2 CDK5RAP2 CRB2 CRB2 NUMA1 NUMA1 PARVA PARVA CRB1 CRB1 MOS MOS PRKCI PRKCI LLGL1 LLGL1 SDCCAG8 SDCCAG8 FSCN1 FSCN1 PKHD1 PKHD1 RHOQ RHOQ CLASP1 CLASP1 PARVB PARVB LOC100607679 LOC100607679 RAB11FIP2 RAB11FIP2 CENPA CENPA SNX27 SNX27 GSK3B GSK3B PDZD11 PDZD11 ENSNLEP00000026584 ENSNLEP00000026584 FSCN2 FSCN2 SPRY1 SPRY1 GOLPH3 GOLPH3 ENSNLEP00000027513 ENSNLEP00000027513 HSP90AB1 HSP90AB1 LHX2 LHX2 SPRY2 SPRY2 ENSNLEP00000027935 ENSNLEP00000027935 ATN1 ATN1 LIN7A LIN7A CKAP5 CKAP5 KIF2C KIF2C PARD3 PARD3 DLG1 DLG1 IFT20 IFT20 FGF10 FGF10 FBXW11 FBXW11 CYTH1 CYTH1 ENSNLEP00000029711 ENSNLEP00000029711 MPP7 MPP7 ENSNLEP00000030327 ENSNLEP00000030327 ENSNLEP00000030410 ENSNLEP00000030410 AMOTL1 AMOTL1 DLG4 DLG4 RHOU RHOU JAM3 JAM3 RHOD RHOD ARF6 ARF6 ENSNLEP00000032181 ENSNLEP00000032181 ENSNLEP00000033007 ENSNLEP00000033007 NDE1 NDE1 CTNNA1 CTNNA1 RND1 RND1 NCKAP1L NCKAP1L PTK2 PTK2 RHOG RHOG ENSNLEP00000036074 ENSNLEP00000036074 PKD1 PKD1 ENSNLEP00000036737 ENSNLEP00000036737 KAT5 KAT5 RPGRIP1L RPGRIP1L GPSM1 GPSM1 MYO18A MYO18A SPDL1 SPDL1 ACTB ACTB CDC42BPB CDC42BPB RHOBTB2 RHOBTB2 MAP1B MAP1B TTC8 TTC8 ARF4 ARF4 DLG2 DLG2 ENSNLEP00000040381 ENSNLEP00000040381 CDC42 CDC42 CRB3 CRB3 ENSNLEP00000041069 ENSNLEP00000041069 RHOB RHOB ENSNLEP00000041120 ENSNLEP00000041120 NSFL1C NSFL1C AMOTL2 AMOTL2 SPN SPN RAC2 RAC2 INSC INSC PAFAH1B1 PAFAH1B1 ENSNLEP00000042609 ENSNLEP00000042609 DLG3 DLG3 FGF13 FGF13 ENSNLEP00000043017 ENSNLEP00000043017 UBXN2B UBXN2B RAC3 RAC3 PAX6 PAX6 RHOF RHOF IGF1R IGF1R WEE1 WEE1 CCR7 CCR7 DST DST LRRC1 LRRC1 MAP4 MAP4 EZR EZR LMNA LMNA CLASP2 CLASP2 ENSNLEP00000046761 ENSNLEP00000046761 ENSNLEP00000046801 ENSNLEP00000046801 RHOC RHOC ZW10 ZW10 ENSNLEP00000047513 ENSNLEP00000047513 MARK2 MARK2 DCTN1 DCTN1 ENSNLEP00000049000 ENSNLEP00000049000 AQP1 AQP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
PRKCZProtein kinase C zeta. (507 aa)
HTTHuntingtin. (3048 aa)
KIF25Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (355 aa)
CDX2Caudal type homeobox 2. (309 aa)
MSNMoesin. (566 aa)
OPHN1Oligophrenin 1. (802 aa)
CRKUncharacterized protein. (252 aa)
BCCIPBRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family. (325 aa)
MISPMitotic spindle positioning. (673 aa)
CAMSAP3CKK domain-containing protein. (248 aa)
CYTH3Cytohesin 3. (399 aa)
OOEPOocyte expressed protein. (149 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (423 aa)
RAB10RAB10, member RAS oncogene family. (200 aa)
SYNJ2BPSynaptojanin 2 binding protein. (145 aa)
FBF1Uncharacterized protein. (936 aa)
SCRIBScribble planar cell polarity protein. (1449 aa)
GPSM2G protein signaling modulator 2. (684 aa)
FRMD4BFERM domain containing 4B. (1034 aa)
SPAG5Sperm associated antigen 5. (1200 aa)
RSKRRibosomal protein S6 kinase related. (410 aa)
ARHGAP35Rho GTPase activating protein 35. (1499 aa)
ERBINErbb2 interacting protein. (1418 aa)
EPHB1EPH receptor B1. (984 aa)
NEK3NIMA related kinase 3. (506 aa)
KIF26BKinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1539 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1078 aa)
CARMIL2Capping protein regulator and myosin 1 linker 2. (1393 aa)
CCL21C-C motif chemokine ligand 21. (134 aa)
PDCD6IPBRO1 domain-containing protein. (903 aa)
PARD6APar-6 family cell polarity regulator alpha. (346 aa)
G1QYG1_NOMLEProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (323 aa)
LIN7BProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (207 aa)
DOCK2Dedicator of cytokinesis 2; Belongs to the DOCK family. (1830 aa)
FAM89BUncharacterized protein. (115 aa)
NT5DC35'-nucleotidase domain containing 3. (548 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (832 aa)
RHOARas homolog family member A. (193 aa)
NDC80NDC80 kinetochore complex component. (642 aa)
LAMA1Laminin subunit alpha 1. (3033 aa)
MTCL1Microtubule crosslinking factor 1. (1675 aa)
PARD6BPar-6 family cell polarity regulator beta. (372 aa)
PARD3BUncharacterized protein. (932 aa)
NT5DC25'-nucleotidase domain containing 2. (558 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
CD3GCD3g molecule. (182 aa)
CRTAMCytotoxic and regulatory T cell molecule. (392 aa)
FEZ1Fasciculation and elongation protein zeta 1. (392 aa)
ANKFN1Uncharacterized protein. (1148 aa)
ALPK2Alpha kinase 2. (2085 aa)
PARD6GPar-6 family cell polarity regulator gamma. (366 aa)
SAPCD2Suppressor APC domain containing 2. (357 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (205 aa)
LRRC7Leucine rich repeat containing 7. (1537 aa)
TCF15Transcription factor 15. (197 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (809 aa)
MAPRE1Microtubule associated protein RP/EB family member 1. (268 aa)
TMEM114Uncharacterized protein. (122 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
SLC9A3R1Uncharacterized protein. (276 aa)
BRSK1UBA domain-containing protein. (449 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1889 aa)
DYNLT1Uncharacterized protein. (106 aa)
FOXF1Uncharacterized protein. (361 aa)
FAT1FAT atypical cadherin 1. (4561 aa)
SYNE4Spectrin repeat containing nuclear envelope family member 4. (401 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (417 aa)
RND2Rho family GTPase 2. (227 aa)
PLK1Serine/threonine-protein kinase PLK. (568 aa)
RHOBTB1Rho related BTB domain containing 1. (696 aa)
FRMD4AFERM domain containing 4A. (962 aa)
FSCN3Fascin. (498 aa)
ANK1Ankyrin 1. (1778 aa)
FAM193BFamily with sequence similarity 193 member B. (752 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1557 aa)
TRAF3IP2TRAF3 interacting protein 2. (542 aa)
PDLIM1PDZ and LIM domain 1. (329 aa)
BRSK2BR serine/threonine kinase 2. (739 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
MYO9AMyosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2548 aa)
STK25Serine/threonine kinase 25. (416 aa)
RHOJRas homolog family member J. (215 aa)
FERMT1Fermitin family member 1. (587 aa)
TMEM53Transmembrane protein 53. (277 aa)
RHOBTB3Rho related BTB domain containing 3. (611 aa)
G1RVW8_NOMLEUncharacterized protein. (281 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1975 aa)
AMOTAngiomotin. (1088 aa)
MAP7Microtubule associated protein 7. (771 aa)
PATJPATJ crumbs cell polarity complex component. (1694 aa)
MCPH1Microcephalin 1. (840 aa)
DOCK7Dedicator of cytokinesis 7; Belongs to the DOCK family. (2104 aa)
GBF1Golgi brefeldin A resistant guanine nucleotide exchange factor 1. (1859 aa)
USTUronyl 2-sulfotransferase. (356 aa)
ACTR3BUncharacterized protein; Belongs to the actin family. (303 aa)
RAC1Rac family small GTPase 1. (187 aa)
PARVGCalponin-homology (CH) domain-containing protein. (168 aa)
G1S1M4_NOMLEDUF4685 domain-containing protein. (1383 aa)
WDR1WD repeat domain 1. (560 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
SIPA1L3Signal induced proliferation associated 1 like 3. (1646 aa)
CDK5RAP2CDK5 regulatory subunit associated protein 2. (1920 aa)
CRB2Uncharacterized protein. (1063 aa)
NUMA1Uncharacterized protein. (947 aa)
PARVAParvin alpha. (345 aa)
CRB1Crumbs cell polarity complex component 1. (1406 aa)
MOSMOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (346 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
LLGL1LLGL scribble cell polarity complex component 1. (968 aa)
SDCCAG8Serologically defined colon cancer antigen 8. (716 aa)
FSCN1Uncharacterized protein. (274 aa)
PKHD1PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4073 aa)
RHOQUncharacterized protein. (190 aa)
CLASP1Cytoplasmic linker associated protein 1. (1538 aa)
PARVBParvin beta. (396 aa)
LOC100607679SCY domain-containing protein. (98 aa)
RAB11FIP2RAB11 family interacting protein 2. (532 aa)
CENPACentromere protein A. (138 aa)
SNX27Sorting nexin 27. (437 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa)
PDZD11PDZ domain containing 11. (140 aa)
ENSNLEP00000026584Uncharacterized protein. (141 aa)
FSCN2Uncharacterized protein. (269 aa)
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)
GOLPH3Golgi phosphoprotein 3. (298 aa)
ENSNLEP00000027513Uncharacterized protein. (154 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (665 aa)
LHX2LIM homeobox 2. (406 aa)
SPRY2Sprouty RTK signaling antagonist 2. (338 aa)
ENSNLEP00000027935Uncharacterized protein. (181 aa)
ATN1Atrophin 1. (1228 aa)
LIN7AProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (233 aa)
CKAP5Cytoskeleton associated protein 5. (2040 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (719 aa)
PARD3Par-3 family cell polarity regulator. (1273 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (916 aa)
IFT20Uncharacterized protein. (148 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FBXW11F-box and WD repeat domain containing 11. (542 aa)
CYTH1Uncharacterized protein. (344 aa)
ENSNLEP00000029711Uncharacterized protein. (230 aa)
MPP7Membrane palmitoylated protein 7; Belongs to the MAGUK family. (576 aa)
ENSNLEP00000030327HORMA domain-containing protein. (98 aa)
ENSNLEP00000030410Uncharacterized protein. (105 aa)
AMOTL1Angiomotin like 1. (962 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (746 aa)
RHOURas homolog family member U. (258 aa)
JAM3Junctional adhesion molecule 3. (275 aa)
RHODRas homolog family member D. (210 aa)
ARF6Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (175 aa)
ENSNLEP00000032181Uncharacterized protein. (103 aa)
ENSNLEP00000033007Uncharacterized protein; Belongs to the actin family. (312 aa)
NDE1NudE neurodevelopment protein 1. (349 aa)
CTNNA1Catenin alpha 1. (895 aa)
RND1Rho family GTPase 1. (214 aa)
NCKAP1LNCK associated protein 1 like. (1109 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1099 aa)
RHOGRas homolog family member G. (191 aa)
ENSNLEP00000036074Uncharacterized protein. (393 aa)
PKD1Uncharacterized protein. (270 aa)
ENSNLEP00000036737Uncharacterized protein. (160 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (535 aa)
RPGRIP1LRPGRIP1 like. (1269 aa)
GPSM1G protein signaling modulator 1. (701 aa)
MYO18AMyosin XVIIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2019 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (595 aa)
ACTBUncharacterized protein. (363 aa)
CDC42BPBCDC42 binding protein kinase beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1699 aa)
RHOBTB2Rho related BTB domain containing 2. (749 aa)
MAP1BMicrotubule associated protein 1B. (2370 aa)
TTC8Tetratricopeptide repeat domain 8. (515 aa)
ARF4ADP ribosylation factor 4; Belongs to the small GTPase superfamily. Arf family. (180 aa)
DLG2Discs large MAGUK scaffold protein 2. (975 aa)
ENSNLEP00000040381Uncharacterized protein. (760 aa)
CDC42Cell division cycle 42. (191 aa)
CRB3Crumbs cell polarity complex component 3. (123 aa)
ENSNLEP00000041069Uncharacterized protein. (115 aa)
RHOBRas homolog family member B. (196 aa)
ENSNLEP00000041120Uncharacterized protein. (106 aa)
NSFL1CNSFL1 cofactor. (337 aa)
AMOTL2Angiomotin like 2. (780 aa)
SPNSialophorin. (400 aa)
RAC2Rac family small GTPase 2. (192 aa)
INSCINSC spindle orientation adaptor protein. (569 aa)
PAFAH1B1Platelet activating factor acetylhydrolase 1b regulatory subunit 1. (370 aa)
ENSNLEP00000042609Uncharacterized protein. (168 aa)
DLG3Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (837 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
ENSNLEP00000043017HATPase_c domain-containing protein. (648 aa)
UBXN2BUBX domain protein 2B. (331 aa)
RAC3Rac family small GTPase 3. (205 aa)
PAX6Uncharacterized protein. (456 aa)
RHOFRas homolog family member F, filopodia associated. (211 aa)
IGF1RTyrosine-protein kinase receptor. (1199 aa)
WEE1Wee1-like protein kinase. (645 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
DSTUncharacterized protein. (7409 aa)
LRRC1Leucine rich repeat containing 1. (503 aa)
MAP4Microtubule-associated protein. (1035 aa)
EZREzrin. (586 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (664 aa)
CLASP2Uncharacterized protein. (1515 aa)
ENSNLEP00000046761Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (151 aa)
ENSNLEP00000046801Protein kinase domain-containing protein. (214 aa)
RHOCRas homolog family member C. (209 aa)
ZW10Zw10 kinetochore protein. (699 aa)
ENSNLEP00000047513UBX domain-containing protein. (304 aa)
MARK2Non-specific serine/threonine protein kinase. (788 aa)
DCTN1CAP-Gly domain-containing protein. (1280 aa)
ENSNLEP00000049000Uncharacterized protein. (110 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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