STRINGSTRING
EXT1 EXT1 SEMA4F SEMA4F ERBB2 ERBB2 NOTCH3 NOTCH3 ENSNLEP00000048801 ENSNLEP00000048801 ENSNLEP00000048664 ENSNLEP00000048664 ENAH ENAH NCAM1 NCAM1 SLIT2 SLIT2 FLRT3 FLRT3 ADAMTSL1 ADAMTSL1 ENSNLEP00000047852 ENSNLEP00000047852 ENSNLEP00000047706 ENSNLEP00000047706 CNTN4 CNTN4 NTRK1 NTRK1 LOC100587986 LOC100587986 CHN1 CHN1 PLXNB3 PLXNB3 ENSNLEP00000045463 ENSNLEP00000045463 CNTN1 CNTN1 B3GNT2 B3GNT2 EGR2 EGR2 FOXD1 FOXD1 SEMA6A SEMA6A PAX6 PAX6 PALLD PALLD NRP2 NRP2 NOG NOG CNTN6 CNTN6 ENSNLEP00000042609 ENSNLEP00000042609 EPHA4 EPHA4 DVL1 DVL1 RAC2 RAC2 EFNA4 EFNA4 EPHB2 EPHB2 LAMA5 LAMA5 EDN3 EDN3 KIF5C KIF5C EFNB2 EFNB2 FYN FYN PLXNA3 PLXNA3 DRGX DRGX EPHA7 EPHA7 DSCAM DSCAM TTC8 TTC8 CXCL12 CXCL12 ROBO1 ROBO1 NRXN1 NRXN1 SEMA3B SEMA3B EFNA2 EFNA2 ETV1 ETV1 RPL24 RPL24 ENSNLEP00000036861 ENSNLEP00000036861 KLF7 KLF7 EMB EMB LAMA2 LAMA2 RHOG RHOG ENSNLEP00000034652 ENSNLEP00000034652 PTK2 PTK2 SEMA4C SEMA4C B4GAT1 B4GAT1 FLRT2 FLRT2 CNTN2 CNTN2 ENSNLEP00000033486 ENSNLEP00000033486 NFIB NFIB ENSNLEP00000032432 ENSNLEP00000032432 MYPN MYPN SIAH1 SIAH1 UNC5A UNC5A TENM2 TENM2 IGSF9 IGSF9 ENSNLEP00000030555 ENSNLEP00000030555 LAMC2 LAMC2 CYFIP1 CYFIP1 ROBO2 ROBO2 ALCAM ALCAM GDNF GDNF EPHA8 EPHA8 ENSNLEP00000028256 ENSNLEP00000028256 ENSNLEP00000027935 ENSNLEP00000027935 LHX2 LHX2 UNC5D UNC5D SEMA3E SEMA3E ENSNLEP00000027355 ENSNLEP00000027355 LYPLA2 LYPLA2 MYCBP2 MYCBP2 APP APP EFNA1 EFNA1 WNT3A WNT3A LHX9 LHX9 TRIO TRIO ENSNLEP00000025453 ENSNLEP00000025453 NRP1 NRP1 CDK5R2 CDK5R2 ATOH1 ATOH1 KIF5B KIF5B LGR6 LGR6 NIBAN2 NIBAN2 ARHGEF25 ARHGEF25 TMEFF1 TMEFF1 NRXN3 NRXN3 PTCH1 PTCH1 FZD3 FZD3 VAX1 VAX1 SOS1 SOS1 CRPPA CRPPA UNC5B UNC5B DPYSL2 DPYSL2 CRMP1 CRMP1 FEZ2 FEZ2 DLX5 DLX5 LHX4 LHX4 RET RET CDH4 CDH4 RAC1 RAC1 TNR TNR EVX1 EVX1 HOXA2 HOXA2 SEMA3D SEMA3D SEMA3A SEMA3A SEMA4G SEMA4G SEMA3C SEMA3C LMX1A LMX1A SEMA7A SEMA7A NFASC NFASC NPTN NPTN NEO1 NEO1 BMPR1B BMPR1B UNC5C UNC5C SLIT1 SLIT1 L1CAM L1CAM SEMA6B SEMA6B PLXNA4 PLXNA4 LGI1 LGI1 SMO SMO SEMA4A SEMA4A FEZF1 FEZF1 GATA3 GATA3 SEMA4B SEMA4B EPHB4 EPHB4 DCC DCC SMAD4 SMAD4 PRKCQ PRKCQ EPHA3 EPHA3 EPHA10 EPHA10 SEMA5A SEMA5A RNF165 RNF165 EFNA5 EFNA5 G1RJA2_NOMLE G1RJA2_NOMLE ISL1 ISL1 GBX2 GBX2 CSF1R CSF1R SEMA6C SEMA6C NEXN NEXN EFNB3 EFNB3 USP33 USP33 DRAXIN DRAXIN NTN3 NTN3 RELN RELN EPHA5 EPHA5 LHX3 LHX3 ANOS1 ANOS1 MYOT MYOT NRCAM NRCAM NOTCH1 NOTCH1 ISL2 ISL2 EPHA2 EPHA2 FEZ1 FEZ1 ROBO4 ROBO4 ROBO3 ROBO3 NECTIN1 NECTIN1 DSCAML1 DSCAML1 WNT5A WNT5A LRTM1 LRTM1 CNTN5 CNTN5 SEMA3G SEMA3G BMP7 BMP7 SEMA3F SEMA3F PTPRM PTPRM LAMA1 LAMA1 DAG1 DAG1 LAMA3 LAMA3 PRTG PRTG PLXNB1 PLXNB1 VSTM2L VSTM2L EPHB3 EPHB3 CCDC141 CCDC141 PLXNC1 PLXNC1 EDNRA EDNRA POU4F2 POU4F2 PLXND1 PLXND1 SLIT3 SLIT3 WNT3 WNT3 NTN5 NTN5 BOC BOC PTK7 PTK7 GBX1 GBX1 CDK5 CDK5 PTPRO PTPRO NKX2-1 NKX2-1 EPHB1 EPHB1 RYK RYK EPHA1 EPHA1 NTF3 NTF3 GLI3 GLI3 G1QS07_NOMLE G1QS07_NOMLE CHL1 CHL1 ARHGAP35 ARHGAP35 EPHB6 EPHB6 LRTM2 LRTM2 GDF7 GDF7 LHX1 LHX1 VASP VASP EPHA6 EPHA6 PLXNA2 PLXNA2 PLA2G10 PLA2G10 PLXNA1 PLXNA1 GLI2 GLI2 EDN1 EDN1 EFNB1 EFNB1 BCL11B BCL11B BSG BSG PLXNB2 PLXNB2 KALRN KALRN SEMA4D SEMA4D SEMA5B SEMA5B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (745 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (683 aa)
ERBB2Receptor protein-tyrosine kinase. (1247 aa)
NOTCH3Notch receptor 3. (2149 aa)
ENSNLEP00000048801Uncharacterized protein. (80 aa)
ENSNLEP00000048664Uncharacterized protein. (194 aa)
ENAHWH1 domain-containing protein. (805 aa)
NCAM1Neural cell adhesion molecule 1. (884 aa)
SLIT2Slit guidance ligand 2. (1389 aa)
FLRT3Fibronectin leucine rich transmembrane protein 3. (649 aa)
ADAMTSL1ADAMTS like 1. (1762 aa)
ENSNLEP00000047852Laminin N-terminal domain-containing protein. (447 aa)
ENSNLEP00000047706Uncharacterized protein. (113 aa)
CNTN4Contactin 4. (1026 aa)
NTRK1Tyrosine-protein kinase receptor. (787 aa)
LOC100587986Olfactory receptor. (260 aa)
CHN1Chimaerin; GTPase-activating protein for p21-rac. (459 aa)
PLXNB3Plexin B3. (1842 aa)
ENSNLEP00000045463Abhydrolase_2 domain-containing protein. (134 aa)
CNTN1Contactin 1. (986 aa)
B3GNT2Hexosyltransferase. (397 aa)
EGR2Early growth response 2. (476 aa)
FOXD1Uncharacterized protein. (241 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
PAX6Uncharacterized protein. (456 aa)
PALLDPalladin, cytoskeletal associated protein. (1123 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (930 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
CNTN6Contactin 6. (999 aa)
ENSNLEP00000042609Uncharacterized protein. (168 aa)
EPHA4EPH receptor A4. (967 aa)
DVL1Dishevelled segment polarity protein 1. (667 aa)
RAC2Rac family small GTPase 2. (192 aa)
EFNA4Ephrin RBD domain-containing protein; Belongs to the ephrin family. (201 aa)
EPHB2EPH receptor B2. (1015 aa)
LAMA5Laminin subunit alpha 5. (3418 aa)
EDN3Uncharacterized protein. (211 aa)
KIF5CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (957 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (299 aa)
FYNTyrosine-protein kinase. (537 aa)
PLXNA3Plexin A3. (1828 aa)
DRGXDorsal root ganglia homeobox. (263 aa)
EPHA7EPH receptor A7. (972 aa)
DSCAMDS cell adhesion molecule. (1827 aa)
TTC8Tetratricopeptide repeat domain 8. (515 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
ROBO1Roundabout guidance receptor 1. (1651 aa)
NRXN1Neurexin 1. (1547 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (770 aa)
EFNA2Ephrin RBD domain-containing protein; Belongs to the ephrin family. (195 aa)
ETV1ETS variant 1. (503 aa)
RPL24Ribosomal protein L24. (157 aa)
ENSNLEP00000036861Uncharacterized protein. (119 aa)
KLF7Uncharacterized protein. (269 aa)
EMBUncharacterized protein. (290 aa)
LAMA2Laminin subunit alpha 2. (3062 aa)
RHOGRas homolog family member G. (191 aa)
ENSNLEP00000034652Uncharacterized protein. (265 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1099 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (833 aa)
B4GAT1Beta-1,4-glucuronyltransferase 1. (415 aa)
FLRT2Fibronectin leucine rich transmembrane protein 2. (660 aa)
CNTN2Contactin 2. (1049 aa)
ENSNLEP00000033486Uncharacterized protein. (126 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (487 aa)
ENSNLEP00000032432Tubulin domain-containing protein. (95 aa)
MYPNUncharacterized protein. (1045 aa)
SIAH1E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa)
UNC5AUnc-5 netrin receptor A. (932 aa)
TENM2Teneurin transmembrane protein 2. (2774 aa)
IGSF9Immunoglobulin superfamily member 9. (1171 aa)
ENSNLEP00000030555Protein kinase domain-containing protein. (200 aa)
LAMC2Laminin subunit gamma 2. (1178 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1228 aa)
ROBO2Roundabout guidance receptor 2. (1199 aa)
ALCAMActivated leukocyte cell adhesion molecule. (590 aa)
GDNFTGF_BETA_2 domain-containing protein. (169 aa)
EPHA8EPH receptor A8. (987 aa)
ENSNLEP00000028256Uncharacterized protein. (80 aa)
ENSNLEP00000027935Uncharacterized protein. (181 aa)
LHX2LIM homeobox 2. (406 aa)
UNC5DUnc-5 netrin receptor D. (958 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (775 aa)
ENSNLEP00000027355Uncharacterized protein. (170 aa)
LYPLA2Abhydrolase_2 domain-containing protein. (185 aa)
MYCBP2MYC binding protein 2. (4726 aa)
APPAmyloid beta precursor protein. (757 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (204 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
LHX9LIM homeobox 9. (382 aa)
TRIOTrio Rho guanine nucleotide exchange factor. (3026 aa)
ENSNLEP00000025453Uncharacterized protein. (56 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (901 aa)
CDK5R2Cyclin-dependent kinase 5 activator. (367 aa)
ATOH1Atonal bHLH transcription factor 1. (354 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
LGR6Leucine rich repeat containing G protein-coupled receptor 6. (896 aa)
NIBAN2PH domain-containing protein. (700 aa)
ARHGEF25Uncharacterized protein. (616 aa)
TMEFF1Uncharacterized protein. (454 aa)
NRXN3Uncharacterized protein. (1061 aa)
PTCH1Patched 1. (1446 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
VAX1Ventral anterior homeobox 1. (334 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
CRPPACDP-L-ribitol pyrophosphorylase A. (403 aa)
UNC5BUnc-5 netrin receptor B. (914 aa)
DPYSL2Dihydropyrimidinase like 2. (572 aa)
CRMP1Collapsin response mediator protein 1. (682 aa)
FEZ2Fasciculation and elongation protein zeta 2. (376 aa)
DLX5Homeobox domain-containing protein. (191 aa)
LHX4Uncharacterized protein. (332 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1114 aa)
CDH4Cadherin 4; Cadherins are calcium-dependent cell adhesion proteins. (893 aa)
RAC1Rac family small GTPase 1. (187 aa)
TNRTenascin R. (1348 aa)
EVX1Even-skipped homeobox 1. (408 aa)
HOXA2Homeobox A2. (376 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (777 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (771 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (793 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (751 aa)
LMX1AUncharacterized protein. (311 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (664 aa)
NFASCNeurofascin. (1337 aa)
NPTNNeuroplastin. (398 aa)
NEO1Neogenin 1. (1461 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
UNC5CUnc-5 netrin receptor C. (876 aa)
SLIT1Slit guidance ligand 1. (1534 aa)
L1CAML1 cell adhesion molecule. (1174 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (857 aa)
PLXNA4Plexin A4. (1864 aa)
LGI1Leucine rich glioma inactivated 1. (557 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (683 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (758 aa)
FEZF1Uncharacterized protein. (337 aa)
GATA3GATA binding protein 3. (444 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (836 aa)
EPHB4EPH receptor B4. (890 aa)
DCCDCC netrin 1 receptor. (1322 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
EPHA3EPH receptor A3. (983 aa)
EPHA10EPH receptor A10. (1080 aa)
SEMA5ASemaphorin 5A. (1074 aa)
RNF165Ring finger protein 165. (346 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
G1RJA2_NOMLEIGv domain-containing protein. (221 aa)
ISL1ISL LIM homeobox 1. (349 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (949 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (921 aa)
NEXNNexilin F-actin binding protein. (675 aa)
EFNB3Ephrin RBD domain-containing protein; Belongs to the ephrin family. (287 aa)
USP33Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (903 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (349 aa)
NTN3Uncharacterized protein. (412 aa)
RELNReelin. (3460 aa)
EPHA5EPH receptor A5. (1038 aa)
LHX3Uncharacterized protein. (367 aa)
ANOS1Anosmin 1. (680 aa)
MYOTMyotilin. (498 aa)
NRCAMNeuronal cell adhesion molecule. (1304 aa)
NOTCH1Notch receptor 1. (2451 aa)
ISL2Homeobox domain-containing protein. (192 aa)
EPHA2EPH receptor A2. (976 aa)
FEZ1Fasciculation and elongation protein zeta 1. (392 aa)
ROBO4Roundabout guidance receptor 4. (984 aa)
ROBO3Roundabout guidance receptor 3. (1308 aa)
NECTIN1Nectin cell adhesion molecule 1. (515 aa)
DSCAML1DS cell adhesion molecule like 1. (1921 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
LRTM1Leucine rich repeats and transmembrane domains 1. (345 aa)
CNTN5Contactin 5. (1100 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (782 aa)
BMP7Bone morphogenetic protein 7. (430 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (788 aa)
PTPRMProtein tyrosine phosphatase receptor type M. (1465 aa)
LAMA1Laminin subunit alpha 1. (3033 aa)
DAG1Dystroglycan 1. (895 aa)
LAMA3Laminin subunit alpha 3. (3316 aa)
PRTGProtogenin. (1149 aa)
PLXNB1Plexin B1. (2079 aa)
VSTM2LV-set and transmembrane domain containing 2 like. (172 aa)
EPHB3EPH receptor B3. (1053 aa)
CCDC141Uncharacterized protein. (955 aa)
PLXNC1Plexin C1. (1305 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
POU4F2POU domain protein. (408 aa)
PLXND1Plexin D1. (1603 aa)
SLIT3Slit guidance ligand 3. (1385 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
NTN5Netrin 5. (468 aa)
BOCBOC cell adhesion associated, oncogene regulated. (1115 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1078 aa)
GBX1Gastrulation brain homeobox 1. (327 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1183 aa)
NKX2-1NK2 homeobox 1. (394 aa)
EPHB1EPH receptor B1. (984 aa)
RYKReceptor like tyrosine kinase. (525 aa)
EPHA1EPH receptor A1. (975 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (268 aa)
GLI3GLI family zinc finger 3. (1502 aa)
G1QS07_NOMLEUncharacterized protein. (248 aa)
CHL1Cell adhesion molecule L1 like. (1225 aa)
ARHGAP35Rho GTPase activating protein 35. (1499 aa)
EPHB6EPH receptor B6. (1019 aa)
LRTM2Leucine rich repeats and transmembrane domains 2. (370 aa)
GDF7Growth differentiation factor 7. (450 aa)
LHX1LIM homeobox 1. (352 aa)
VASPVasodilator stimulated phosphoprotein. (341 aa)
EPHA6EPH receptor A6. (1130 aa)
PLXNA2Plexin A2. (1909 aa)
PLA2G10Phospholipase A(2). (129 aa)
PLXNA1Plexin A1. (1880 aa)
GLI2GLI family zinc finger 2. (1589 aa)
EDN1Endothelin 1. (211 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (346 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (864 aa)
BSGUncharacterized protein. (345 aa)
PLXNB2Plexin B2. (1647 aa)
KALRNUncharacterized protein. (2931 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
SEMA5BSemaphorin 5B. (1090 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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