STRINGSTRING
ITGA8 ITGA8 LOC100600501 LOC100600501 SYT11 SYT11 PTEN PTEN ATAD1 ATAD1 PPT1 PPT1 DKK1 DKK1 PTPRZ1 PTPRZ1 EN1 EN1 FOXB1 FOXB1 CAMK4 CAMK4 PRKN PRKN CHRNB2 CHRNB2 TACR2 TACR2 GLP1R GLP1R KAT2A KAT2A MEIS2 MEIS2 PRKCZ PRKCZ HTT HTT INSR INSR CUX2 CUX2 ADGRB3 ADGRB3 NPS NPS KALRN KALRN RPS6KB1 RPS6KB1 NEUROD2 NEUROD2 PPP1R1B PPP1R1B PTRHD1 PTRHD1 ATXN1 ATXN1 ADCY3 ADCY3 ABCA7 ABCA7 SHANK3 SHANK3 CCL11 CCL11 CLN3 CLN3 TBR1-2 TBR1-2 GALR2 GALR2 BRAF BRAF CALB1 CALB1 PLK2 PLK2 GIP GIP PAK6 PAK6 CCND2 CCND2 G1QS13_NOMLE G1QS13_NOMLE FEN1 FEN1 UCN UCN NTF3 NTF3 NDRG4 NDRG4 SLC6A4 SLC6A4 NTRK2 NTRK2 MME MME GRIN2B GRIN2B CDK5 CDK5 G1QVV4_NOMLE G1QVV4_NOMLE PTCHD4 PTCHD4 G1QVV6_NOMLE G1QVV6_NOMLE SRF SRF ADGRF1 ADGRF1 BCHE BCHE NTF4 NTF4 TREM2 TREM2 MAP1A MAP1A NRXN2 NRXN2 KRAS KRAS GHSR GHSR SHANK1 SHANK1 KLK8 KLK8 FOSL1 FOSL1 NPAS4 NPAS4 PRKCG PRKCG TMOD2 TMOD2 PRRT1 PRRT1 HRH4 HRH4 DNAAF4 DNAAF4 AGER AGER ABI2 ABI2 CREB1 CREB1 TTC36 TTC36 NRGN NRGN OXT OXT CHRNA7 CHRNA7 VDAC1 VDAC1 SLC2A4 SLC2A4 PRKAR1B PRKAR1B KIT KIT VLDLR VLDLR RASGRF1 RASGRF1 ITGA3 ITGA3 PAIP2 PAIP2 UBA6 UBA6 RELN RELN NETO1 NETO1 GRPR GRPR NTSR1 NTSR1 PTCHD1 PTCHD1 NTAN1 NTAN1 BRSK1 BRSK1 CIC CIC NPTX2 NPTX2 SYT4 SYT4 BTBD9 BTBD9 ABCC8 ABCC8 GIT1 GIT1 RIC8A RIC8A GRIN2A GRIN2A CPEB3 CPEB3 EPHB2 EPHB2 CX3CR1 CX3CR1 ENSNLEP00000042687 ENSNLEP00000042687 NOG NOG FGF13 FGF13 SCN2A SCN2A B4GALT2 B4GALT2 NLGN4X NLGN4X TH TH MUSK MUSK EGR2 EGR2 SLC1A1 SLC1A1 TPBG TPBG S100B S100B UBE3A UBE3A DGKI DGKI SLC8A3 SLC8A3 ADCY1 ADCY1 ENSNLEP00000046761 ENSNLEP00000046761 ENSNLEP00000047083 ENSNLEP00000047083 CAMK2N1 CAMK2N1 NTRK1 NTRK1 DNAH11 DNAH11 NRXN3 NRXN3 BRINP1 BRINP1 TAFA2 TAFA2 CTNS CTNS ZZEF1 ZZEF1 PDE1B PDE1B ITGA5 ITGA5 AAAS AAAS BDNF BDNF RAPGEF3 RAPGEF3 RAG1 RAG1 PTGS2 PTGS2 ATXN1L ATXN1L NEUROG1 NEUROG1 FZD9 FZD9 HRH1 HRH1 ZNF385A ZNF385A PJA2 PJA2 ADNP ADNP LOC100600842 LOC100600842 PRNP PRNP ELAVL4 ELAVL4 BTG2 BTG2 SLC11A2 SLC11A2 SYNGAP1 SYNGAP1 CRTC1 CRTC1 SERPINF1 SERPINF1 GATM GATM ENSNLEP00000025821 ENSNLEP00000025821 ENSNLEP00000025893 ENSNLEP00000025893 APP APP TACR1 TACR1 PTN PTN PPP3CB PPP3CB MAPK1 MAPK1 ENSNLEP00000027702 ENSNLEP00000027702 CSMD2 CSMD2 IFT20 IFT20 SLC12A5 SLC12A5 NGF NGF GM2A GM2A DRD2 DRD2 STRA6 STRA6 LOC100597720 LOC100597720 PSEN1 PSEN1 ENSNLEP00000031077 ENSNLEP00000031077 DLG4 DLG4 SYNJ1 SYNJ1 GRM5 GRM5 CRH CRH AMFR AMFR ENSNLEP00000032035 ENSNLEP00000032035 LHX8 LHX8 ARL6IP5 ARL6IP5 GRIA1 GRIA1 PRKAR2B PRKAR2B ENSNLEP00000032971 ENSNLEP00000032971 SPG11 SPG11 CNTN2 CNTN2 MAPK8IP2 MAPK8IP2 GPR88 GPR88 MEF2C MEF2C CLN8 CLN8 FEN1-2 FEN1-2 ENSNLEP00000035134 ENSNLEP00000035134 TIFAB TIFAB GABRA5 GABRA5 EGFR EGFR EIF4A3 EIF4A3 VIP VIP EP300 EP300 MECP2 MECP2 EIF2AK4 EIF2AK4 PLA2G6 PLA2G6 ENSNLEP00000036861 ENSNLEP00000036861 TACO1 TACO1 PPP1R9B PPP1R9B GRIN1 GRIN1 SHANK2 SHANK2 B2M B2M CSMD1 CSMD1 LGMN LGMN NRXN1 NRXN1 ADCY8 ADCY8 LDLR LDLR NLGN3 NLGN3 DRD1 DRD1 HTR2A HTR2A NEDD9 NEDD9 ITPR3 ITPR3 TBR1 TBR1 ARF4 ARF4 NF1 NF1 ASIC1 ASIC1 NFATC4 NFATC4 PICALM PICALM FYN FYN ENSNLEP00000041070 ENSNLEP00000041070 EHMT2 EHMT2 FOS FOS ENSNLEP00000047564 ENSNLEP00000047564 ATP1A2 ATP1A2 KCNK10 KCNK10 YTHDF1 YTHDF1 SRC SRC HIF1A HIF1A OXTR OXTR ENSNLEP00000048868 ENSNLEP00000048868 ATP8A1 ATP8A1 EIF4EBP2 EIF4EBP2 TNR TNR SORCS3 SORCS3 EPM2A EPM2A JPH4 JPH4 SGK1 SGK1 LMX1A LMX1A SNAP25 SNAP25 PAK5 PAK5 CHST10 CHST10 KCNK2 KCNK2 NPTN NPTN PLCB1 PLCB1 LRRN4 LRRN4 SLC7A11 SLC7A11 NCSTN NCSTN AFF2 AFF2 SPECC1 SPECC1 DBH DBH POMK POMK TSC1 TSC1 RGS14 RGS14 ABL1 ABL1 ADAM2 ADAM2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1048 aa)
LOC100600501WWE domain-containing protein. (218 aa)
SYT11Synaptotagmin 11. (431 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
ATAD1ATPase family AAA domain containing 1; Belongs to the AAA ATPase family. (364 aa)
PPT1Palmitoyl-protein thioesterase 1. (326 aa)
DKK1Dickkopf-like protein 1. (266 aa)
PTPRZ1Protein tyrosine phosphatase receptor type Z1. (2315 aa)
EN1Homeobox protein engrailed-like. (298 aa)
FOXB1Forkhead box B1. (325 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (473 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (437 aa)
CHRNB2Uncharacterized protein. (329 aa)
TACR2Tachykinin receptor 2; Belongs to the G-protein coupled receptor 1 family. (393 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (462 aa)
KAT2AUncharacterized protein. (476 aa)
MEIS2Meis homeobox 2. (477 aa)
PRKCZProtein kinase C zeta. (507 aa)
HTTHuntingtin. (3048 aa)
INSRInsulin receptor. (1232 aa)
CUX2Homeobox protein cut-like. (1480 aa)
ADGRB3Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family. (1522 aa)
NPSNeuropeptide S. (89 aa)
KALRNUncharacterized protein. (2931 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (513 aa)
NEUROD2Neurogenic differentiation factor. (364 aa)
PPP1R1BProtein phosphatase 1 regulatory inhibitor subunit 1B. (204 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ATXN1Ataxin 1. (800 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1131 aa)
ABCA7Uncharacterized protein. (1829 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1521 aa)
CCL11C-C motif chemokine. (97 aa)
CLN3Battenin. (384 aa)
TBR1-2Uncharacterized protein. (231 aa)
GALR2Galanin receptor 2; Belongs to the G-protein coupled receptor 1 family. (387 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (764 aa)
CALB1Calbindin 1. (261 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
GIPGastric inhibitory polypeptide. (153 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
CCND2Cyclin_C domain-containing protein. (240 aa)
G1QS13_NOMLEUncharacterized protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (481 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
UCNUrocortin. (124 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (268 aa)
NDRG4NDRG family member 4. (391 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (625 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
MMEMembrane metalloendopeptidase. (750 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1335 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa)
G1QVV4_NOMLEGuanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (292 aa)
PTCHD4Patched domain containing 4. (846 aa)
G1QVV6_NOMLEProtein kinase domain-containing protein. (695 aa)
SRFSerum response factor. (508 aa)
ADGRF1Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (774 aa)
BCHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (602 aa)
NTF4Neurotrophin 4; Belongs to the NGF-beta family. (210 aa)
TREM2Ig-like domain-containing protein. (222 aa)
MAP1AMicrotubule associated protein 1A. (3040 aa)
NRXN2Neurexin 2. (1626 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
SHANK1Uncharacterized protein. (1415 aa)
KLK8Kallikrein related peptidase 8; Belongs to the peptidase S1 family. (305 aa)
FOSL1BZIP domain-containing protein. (271 aa)
NPAS4Neuronal PAS domain protein 4. (802 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
TMOD2Tropomodulin 2. (351 aa)
PRRT1Proline rich transmembrane protein 1. (263 aa)
HRH4G_PROTEIN_RECEP_F1_2 domain-containing protein. (264 aa)
DNAAF4Dynein axonemal assembly factor 4. (420 aa)
AGERAdvanced glycosylation end-product specific receptor. (404 aa)
ABI2Abl interactor 2. (462 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
TTC36Tetratricopeptide repeat domain 36. (191 aa)
NRGNNeurogranin. (78 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (124 aa)
CHRNA7Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (358 aa)
VDAC1Voltage dependent anion channel 1. (282 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (481 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (320 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (969 aa)
VLDLRVery low density lipoprotein receptor. (873 aa)
RASGRF1Ras protein specific guanine nucleotide releasing factor 1. (1243 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1050 aa)
PAIP2Poly(A) binding protein interacting protein 2. (124 aa)
UBA6Ubiquitin like modifier activating enzyme 6. (1052 aa)
RELNReelin. (3460 aa)
NETO1Neuropilin and tolloid like 1. (525 aa)
GRPRGastrin releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa)
NTSR1Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
PTCHD1Patched domain containing 1. (888 aa)
NTAN1N-terminal asparagine amidase. (294 aa)
BRSK1UBA domain-containing protein. (449 aa)
CICHMG box domain-containing protein. (2385 aa)
NPTX2Uncharacterized protein. (321 aa)
SYT4Synaptotagmin 4. (425 aa)
BTBD9BTB domain containing 9. (612 aa)
ABCC8ATP binding cassette subfamily C member 8. (1569 aa)
GIT1GIT ArfGAP 1. (772 aa)
RIC8ARIC8 guanine nucleotide exchange factor A. (536 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
CPEB3Cytoplasmic polyadenylation element binding protein 3. (717 aa)
EPHB2EPH receptor B2. (1015 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (386 aa)
ENSNLEP00000042687Uncharacterized protein. (245 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1939 aa)
B4GALT2Uncharacterized protein. (320 aa)
NLGN4XNeuroligin 4 X-linked. (836 aa)
THTyrosine hydroxylase. (507 aa)
MUSKMuscle associated receptor tyrosine kinase. (881 aa)
EGR2Early growth response 2. (476 aa)
SLC1A1Amino acid transporter. (457 aa)
TPBGTrophoblast glycoprotein. (384 aa)
S100BS_100 domain-containing protein; Belongs to the S-100 family. (94 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (881 aa)
DGKIDiacylglycerol kinase. (1026 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
ADCY1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (338 aa)
ENSNLEP00000046761Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (151 aa)
ENSNLEP00000047083Uncharacterized protein. (267 aa)
CAMK2N1Uncharacterized protein. (43 aa)
NTRK1Tyrosine-protein kinase receptor. (787 aa)
DNAH11Dynein axonemal heavy chain 11. (4498 aa)
NRXN3Uncharacterized protein. (1061 aa)
BRINP1BMP/retinoic acid inducible neural specific 1. (761 aa)
TAFA2TAFA chemokine like family member 2. (131 aa)
CTNSCystinosin, lysosomal cystine transporter. (400 aa)
ZZEF1Zinc finger ZZ-type and EF-hand domain containing 1. (2918 aa)
PDE1BPhosphodiesterase. (536 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1038 aa)
AAASAladin WD repeat nucleoporin. (546 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (329 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (853 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
ATXN1LAtaxin 1 like. (689 aa)
NEUROG1Neurogenin 1. (237 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
HRH1Histamine receptor H1; Belongs to the G-protein coupled receptor 1 family. (487 aa)
ZNF385AZinc finger protein 385A. (372 aa)
PJA2Praja ring finger ubiquitin ligase 2. (708 aa)
ADNPActivity dependent neuroprotector homeobox. (1102 aa)
LOC100600842DDHD domain-containing protein. (295 aa)
PRNPMajor prion protein; Belongs to the prion family. (253 aa)
ELAVL4ELAV-like protein; Belongs to the RRM elav family. (402 aa)
BTG2BTG anti-proliferation factor 2. (158 aa)
SLC11A2Solute carrier family 11 member 2. (568 aa)
SYNGAP1Ras-GAP domain-containing protein. (1226 aa)
CRTC1CREB regulated transcription coactivator 1. (619 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (366 aa)
GATMGlycine amidinotransferase. (423 aa)
ENSNLEP00000025821FERM_f0 domain-containing protein. (129 aa)
ENSNLEP00000025893Uncharacterized protein. (271 aa)
APPAmyloid beta precursor protein. (757 aa)
TACR1Tachykinin receptor 1. (406 aa)
PTNPleiotrophin. (172 aa)
PPP3CBSerine/threonine-protein phosphatase. (408 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
ENSNLEP00000027702Uncharacterized protein. (381 aa)
CSMD2CUB and Sushi multiple domains 2. (3507 aa)
IFT20Uncharacterized protein. (148 aa)
SLC12A5Solute carrier family 12 member 5. (1139 aa)
NGFNGF domain-containing protein; Belongs to the NGF-beta family. (123 aa)
GM2AGM2 ganglioside activator. (193 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (445 aa)
STRA6Stimulated by retinoic acid 6. (636 aa)
LOC100597720Uncharacterized protein. (278 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
ENSNLEP00000031077Neur_chan_LBD domain-containing protein. (158 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (746 aa)
SYNJ1Synaptojanin 1. (1383 aa)
GRM5Glutamate metabotropic receptor 5. (1210 aa)
CRHCorticotropin releasing hormone. (196 aa)
AMFRAutocrine motility factor receptor. (636 aa)
ENSNLEP00000032035Uncharacterized protein. (107 aa)
LHX8LIM homeobox 8. (377 aa)
ARL6IP5PRA1 family protein. (188 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (916 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (343 aa)
ENSNLEP00000032971Uncharacterized protein. (271 aa)
SPG11SPG11 vesicle trafficking associated, spatacsin. (2443 aa)
CNTN2Contactin 2. (1049 aa)
MAPK8IP2PID domain-containing protein. (178 aa)
GPR88G_PROTEIN_RECEP_F1_2 domain-containing protein. (231 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
CLN8CLN8 transmembrane ER and ERGIC protein. (286 aa)
FEN1-2Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (341 aa)
ENSNLEP00000035134Uncharacterized protein. (101 aa)
TIFABTIFA inhibitor. (162 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
EGFRReceptor protein-tyrosine kinase. (1206 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (411 aa)
VIPVasoactive intestinal peptide. (170 aa)
EP300E1A binding protein p300. (2306 aa)
MECP2MBD domain-containing protein. (156 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1642 aa)
PLA2G6Phospholipase A2 group VI. (805 aa)
ENSNLEP00000036861Uncharacterized protein. (119 aa)
TACO1Translational activator of cytochrome c oxidase I. (297 aa)
PPP1R9BProtein phosphatase 1 regulatory subunit 9B. (813 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (888 aa)
SHANK2SH3 and multiple ankyrin repeat domains 2. (1261 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa)
CSMD1CUB and Sushi multiple domains 1. (3565 aa)
LGMNLegumain. (414 aa)
NRXN1Neurexin 1. (1547 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
LDLRUncharacterized protein. (839 aa)
NLGN3Neuroligin 3. (912 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
HTR2A5-hydroxytryptamine receptor 2A. (471 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (838 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2755 aa)
TBR1T-box_assoc domain-containing protein. (243 aa)
ARF4ADP ribosylation factor 4; Belongs to the small GTPase superfamily. Arf family. (180 aa)
NF1Neurofibromin 1. (2839 aa)
ASIC1Acid sensing ion channel subunit 1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (479 aa)
NFATC4Nuclear factor of activated T cells 4. (844 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (669 aa)
FYNTyrosine-protein kinase. (537 aa)
ENSNLEP00000041070Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (703 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1122 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
ENSNLEP00000047564Uncharacterized protein. (204 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
KCNK10Potassium two pore domain channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (545 aa)
YTHDF1Uncharacterized protein. (52 aa)
SRCTyrosine-protein kinase. (537 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (389 aa)
ENSNLEP00000048868AAA domain-containing protein. (306 aa)
ATP8A1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1164 aa)
EIF4EBP2Uncharacterized protein. (120 aa)
TNRTenascin R. (1348 aa)
SORCS3Sortilin related VPS10 domain containing receptor 3. (1222 aa)
EPM2AEPM2A glucan phosphatase, laforin. (331 aa)
JPH4Junctophilin 4. (613 aa)
SGK1Non-specific serine/threonine protein kinase. (526 aa)
LMX1AUncharacterized protein. (311 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
CHST10Carbohydrate sulfotransferase. (356 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
NPTNNeuroplastin. (398 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
LRRN4Fibronectin type-III domain-containing protein. (562 aa)
SLC7A11Solute carrier family 7 member 11. (500 aa)
NCSTNNicastrin. (702 aa)
AFF2AF4/FMR2 family member 2. (1311 aa)
SPECC1Sperm antigen with calponin homology and coiled-coil domains 1. (1068 aa)
DBHDopamine beta-hydroxylase. (611 aa)
POMKProtein O-mannose kinase. (350 aa)
TSC1TSC complex subunit 1. (1164 aa)
RGS14Regulator of G protein signaling 14. (565 aa)
ABL1Tyrosine-protein kinase. (1006 aa)
ADAM2ADAM metallopeptidase domain 2. (735 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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