STRINGSTRING
ENSNLEP00000027720 ENSNLEP00000027720 ADM2 ADM2 CALCA CALCA HCRTR1 HCRTR1 TBR1-2 TBR1-2 GALR2 GALR2 GCG GCG BRS3 BRS3 UCN UCN GFRAL GFRAL HCRTR2 HCRTR2 RMI1 RMI1 NTRK2 NTRK2 GHRL GHRL CARTPT CARTPT AGRP AGRP IAPP IAPP CNTFR CNTFR UBR3 UBR3 TRH TRH GHSR GHSR PYY PYY CCK CCK PMCH PMCH NPY1R NPY1R HRH4 HRH4 GAL GAL HAND2 HAND2 BSX BSX OXT OXT MMP17 MMP17 DERL2 DERL2 NEGR1 NEGR1 ACE2 ACE2 PEX13 PEX13 OPRD1 OPRD1 PRLH PRLH HELT HELT HCRT HCRT UBE2Q1 UBE2Q1 STAT3 STAT3 EN1 EN1 LEP LEP MRAP2 MRAP2 ATP8A2 ATP8A2 REN REN ADORA2A ADORA2A DACH1 DACH1 DMBX1 DMBX1 NMUR2 NMUR2 SLC24A4 SLC24A4 BBS12 BBS12 MC4R MC4R P2RY1 P2RY1 APP APP TACR1 TACR1 NPSR1 NPSR1 DRD2 DRD2 STRA6 STRA6 GDF15 GDF15 BBIP1 BBIP1 CNTN2 CNTN2 HTR2C HTR2C GPR83 GPR83 ENSNLEP00000035827 ENSNLEP00000035827 ENSNLEP00000037382 ENSNLEP00000037382 DRD1 DRD1 TBR1 TBR1 NPB NPB FYN FYN UCHL1 UCHL1 GLS GLS ENSNLEP00000044511 ENSNLEP00000044511 TH TH PRLHR PRLHR CPT1A CPT1A FOS FOS OXTR OXTR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSNLEP00000027720Uncharacterized protein. (82 aa)
ADM2Adrenomedullin 2. (148 aa)
CALCACalcitonin related polypeptide alpha. (141 aa)
HCRTR1Hypocretin receptor 1; Belongs to the G-protein coupled receptor 1 family. (425 aa)
TBR1-2Uncharacterized protein. (231 aa)
GALR2Galanin receptor 2; Belongs to the G-protein coupled receptor 1 family. (387 aa)
GCGGlucagon. (180 aa)
BRS3Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family. (399 aa)
UCNUrocortin. (124 aa)
GFRALGDNF family receptor alpha like. (393 aa)
HCRTR2Hypocretin receptor 2; Belongs to the G-protein coupled receptor 1 family. (444 aa)
RMI1RecQ mediated genome instability 1. (625 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
CARTPTCART prepropeptide. (116 aa)
AGRPAgouti related neuropeptide. (132 aa)
IAPPIslet amyloid polypeptide. (89 aa)
CNTFRCiliary neurotrophic factor receptor. (372 aa)
UBR3E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1868 aa)
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (242 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
PYYPeptide YY. (97 aa)
CCKCholecystokinin. (115 aa)
PMCHPro-melanin concentrating hormone. (165 aa)
NPY1RNeuropeptide Y receptor Y1; Belongs to the G-protein coupled receptor 1 family. (383 aa)
HRH4G_PROTEIN_RECEP_F1_2 domain-containing protein. (264 aa)
GALGalanin and GMAP prepropeptide. (123 aa)
HAND2Heart and neural crest derivatives expressed 2. (198 aa)
BSXBrain specific homeobox. (232 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (124 aa)
MMP17Matrix metallopeptidase 17. (607 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
NEGR1Neuronal growth regulator 1. (354 aa)
ACE2Angiotensin-converting enzyme. (805 aa)
PEX13Peroxisomal biogenesis factor 13. (393 aa)
OPRD1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (265 aa)
PRLHProlactin releasing hormone. (87 aa)
HELTUncharacterized protein. (327 aa)
HCRTOrexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family. (131 aa)
UBE2Q1Ubiquitin conjugating enzyme E2 Q1. (422 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
EN1Homeobox protein engrailed-like. (298 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
MRAP2Melanocortin 2 receptor accessory protein 2. (205 aa)
ATP8A2Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1161 aa)
RENRenin; Belongs to the peptidase A1 family. (388 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
DACH1Dachshund family transcription factor 1. (760 aa)
DMBX1Diencephalon/mesencephalon homeobox 1. (377 aa)
NMUR2Neuromedin U receptor 2; Belongs to the G-protein coupled receptor 1 family. (403 aa)
SLC24A4Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (622 aa)
BBS12Bardet-Biedl syndrome 12. (710 aa)
MC4RMelanocortin 4 receptor. (332 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
APPAmyloid beta precursor protein. (757 aa)
TACR1Tachykinin receptor 1. (406 aa)
NPSR1Neuropeptide S receptor 1. (391 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (445 aa)
STRA6Stimulated by retinoic acid 6. (636 aa)
GDF15Growth differentiation factor 15. (308 aa)
BBIP1BBSome interacting protein 1. (103 aa)
CNTN2Contactin 2. (1049 aa)
HTR2C5-hydroxytryptamine receptor 2C. (458 aa)
GPR83G protein-coupled receptor 83; Belongs to the G-protein coupled receptor 1 family. (423 aa)
ENSNLEP00000035827G_PROTEIN_RECEP_F1_2 domain-containing protein. (308 aa)
ENSNLEP00000037382Uncharacterized protein; Belongs to the NPY family. (89 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
TBR1T-box_assoc domain-containing protein. (243 aa)
NPBUncharacterized protein. (107 aa)
FYNTyrosine-protein kinase. (537 aa)
UCHL1Ubiquitin carboxyl-terminal hydrolase. (223 aa)
GLSEF-hand_14 domain-containing protein. (558 aa)
ENSNLEP00000044511POU domain protein. (242 aa)
THTyrosine hydroxylase. (507 aa)
PRLHRProlactin releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family. (370 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (680 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (389 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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