Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AADACL3 | KMO | ENSNLEP00000025966 | ENSNLEP00000025703 | Arylacetamide deacetylase like 3. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. | 0.446 |
| AADACL3 | KYNU | ENSNLEP00000025966 | ENSNLEP00000010945 | Arylacetamide deacetylase like 3. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. | 0.606 |
| AADACL3 | TDO2 | ENSNLEP00000025966 | ENSNLEP00000007627 | Arylacetamide deacetylase like 3. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.591 |
| AADACL4 | KMO | ENSNLEP00000011988 | ENSNLEP00000025703 | Uncharacterized protein. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. | 0.446 |
| AADACL4 | KYNU | ENSNLEP00000011988 | ENSNLEP00000010945 | Uncharacterized protein. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. | 0.606 |
| AADACL4 | TDO2 | ENSNLEP00000011988 | ENSNLEP00000007627 | Uncharacterized protein. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.591 |
| AADAT | AASS | ENSNLEP00000008087 | ENSNLEP00000014597 | Aminoadipate aminotransferase. | Aminoadipate-semialdehyde synthase. | 0.465 |
| AADAT | ACMSD | ENSNLEP00000008087 | ENSNLEP00000010256 | Aminoadipate aminotransferase. | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. | 0.482 |
| AADAT | BCAT2 | ENSNLEP00000008087 | ENSNLEP00000005654 | Aminoadipate aminotransferase. | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.840 |
| AADAT | DLST | ENSNLEP00000008087 | ENSNLEP00000019834 | Aminoadipate aminotransferase. | Dihydrolipoamide S-succinyltransferase. | 0.908 |
| AADAT | G1RWH5_NOMLE | ENSNLEP00000008087 | ENSNLEP00000017602 | Aminoadipate aminotransferase. | Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.411 |
| AADAT | GOT1 | ENSNLEP00000008087 | ENSNLEP00000017746 | Aminoadipate aminotransferase. | Aspartate aminotransferase. | 0.435 |
| AADAT | HAAO | ENSNLEP00000008087 | ENSNLEP00000020275 | Aminoadipate aminotransferase. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.571 |
| AADAT | HPD | ENSNLEP00000008087 | ENSNLEP00000028189 | Aminoadipate aminotransferase. | 4-hydroxyphenylpyruvate dioxygenase. | 0.512 |
| AADAT | IDO1 | ENSNLEP00000008087 | ENSNLEP00000015225 | Aminoadipate aminotransferase. | Indoleamine 2,3-dioxygenase 1. | 0.459 |
| AADAT | KMO | ENSNLEP00000008087 | ENSNLEP00000025703 | Aminoadipate aminotransferase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. | 0.962 |
| AADAT | KYAT3 | ENSNLEP00000008087 | ENSNLEP00000012467 | Aminoadipate aminotransferase. | Kynurenine aminotransferase 3. | 0.933 |
| AADAT | KYNU | ENSNLEP00000008087 | ENSNLEP00000010945 | Aminoadipate aminotransferase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. | 0.612 |
| AADAT | TDO2 | ENSNLEP00000008087 | ENSNLEP00000007627 | Aminoadipate aminotransferase. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.521 |
| AASS | AADAT | ENSNLEP00000014597 | ENSNLEP00000008087 | Aminoadipate-semialdehyde synthase. | Aminoadipate aminotransferase. | 0.465 |
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