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| | DGUOK | Deoxyguanosine kinase. (277 aa) |
| | AK4 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (223 aa) |
| | ELOVL5 | Elongation of very long chain fatty acids protein. (326 aa) |
| | PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2. (619 aa) |
| | ENSNLEP00000048727 | Uncharacterized protein. (283 aa) |
| | AMPD3 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (776 aa) |
| | TK2 | Thymidine kinase 2. (296 aa) |
| | SLC25A1 | Solute carrier family 25 member 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (259 aa) |
| | ADCY5 | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1262 aa) |
| | GUK1 | Guanylate kinase-like domain-containing protein. (272 aa) |
| | LOC100582337 | Nucleoside diphosphate kinase. (147 aa) |
| | CMPK2 | Thymidylate_kin domain-containing protein. (379 aa) |
| | ADCY1 | Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (338 aa) |
| | TECR | S5A_REDUCTASE domain-containing protein. (319 aa) |
| | PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1. (624 aa) |
| | ATP5F1C | ATP synthase subunit gamma. (325 aa) |
| | ENSNLEP00000045608 | Uncharacterized protein. (362 aa) |
| | ENSNLEP00000045228 | ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (141 aa) |
| | MTHFD1 | Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (990 aa) |
| | ENSNLEP00000044748 | Uncharacterized protein. (374 aa) |
| | ENSNLEP00000044481 | Uncharacterized protein. (241 aa) |
| | NMRK1 | Nicotinamide riboside kinase 1. (210 aa) |
| | ENSNLEP00000044316 | Uncharacterized protein; Belongs to the adenylate kinase family. (134 aa) |
| | AK6 | Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (172 aa) |
| | UPRT | Uncharacterized protein. (173 aa) |
| | ENSNLEP00000043892 | Uncharacterized protein. (162 aa) |
| | ENSNLEP00000043839 | Uncharacterized protein. (93 aa) |
| | KARS1 | Lysine--tRNA ligase. (629 aa) |
| | ATP5MPL | Uncharacterized protein. (98 aa) |
| | ATP5PO | Uncharacterized protein. (213 aa) |
| | ENSNLEP00000043038 | Uncharacterized protein. (67 aa) |
| | ENSNLEP00000042998 | Uncharacterized protein. (354 aa) |
| | ATP5F1A | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (545 aa) |
| | HACD1 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (288 aa) |
| | ENSNLEP00000042826 | Uncharacterized protein. (217 aa) |
| | ADSL | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (498 aa) |
| | ATP5MD | ATP synthase membrane subunit DAPIT. (58 aa) |
| | ELOVL7 | Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (281 aa) |
| | ACOT7 | Uncharacterized protein. (472 aa) |
| | ENSNLEP00000041332 | Uncharacterized protein. (126 aa) |
| | ENSNLEP00000041062 | Uncharacterized protein. (151 aa) |
| | ENSNLEP00000041001 | dUTPase domain-containing protein. (155 aa) |
| | ENSNLEP00000040993 | Uncharacterized protein. (521 aa) |
| | GMPR2 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (395 aa) |
| | ACSL6 | AMP-binding domain-containing protein. (700 aa) |
| | LOC100581732 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (581 aa) |
| | IMPDH | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (516 aa) |
| | DLG2 | Discs large MAGUK scaffold protein 2. (975 aa) |
| | ENSNLEP00000040238 | Uncharacterized protein. (384 aa) |
| | ENSNLEP00000038989 | Uncharacterized protein. (64 aa) |
| | ENSNLEP00000038878 | ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (127 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa) |
| | NAPRT | Nicotinate phosphoribosyltransferase. (602 aa) |
| | RRM2 | Ribonucleotide reductase regulatory subunit M2. (448 aa) |
| | FCSK | Fucose kinase. (1097 aa) |
| | MTHFD2L | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. (347 aa) |
| | ACSS2 | Acyl-CoA synthetase short chain family member 2. (714 aa) |
| | RRM2B | Ribonucleotide reductase regulatory TP53 inducible subunit M2B. (355 aa) |
| | ADSS2 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (458 aa) |
| | LOC100585501 | IMPDH domain-containing protein. (529 aa) |
| | ENSNLEP00000036022 | CTP_transf_like domain-containing protein. (256 aa) |
| | ENSNLEP00000035724 | Uncharacterized protein. (122 aa) |
| | NME6 | Nucleoside diphosphate kinase. (194 aa) |
| | DCK | dNK domain-containing protein. (317 aa) |
| | IMPDH1 | CBS domain-containing protein. (487 aa) |
| | ENSNLEP00000034659 | Uncharacterized protein. (407 aa) |
| | RFK | Riboflavin kinase. (162 aa) |
| | ENSNLEP00000034358 | Uncharacterized protein. (268 aa) |
| | ENSNLEP00000034323 | S5A_REDUCTASE domain-containing protein. (264 aa) |
| | SLC25A16 | Solute carrier family 25 member 16; Belongs to the mitochondrial carrier (TC 2.A.29) family. (331 aa) |
| | NDUFB2 | NADH:ubiquinone oxidoreductase subunit B2. (105 aa) |
| | PAICS | AIRC domain-containing protein. (451 aa) |
| | ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1310 aa) |
| | ENSNLEP00000033214 | Uncharacterized protein. (72 aa) |
| | ATP5PF | ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (119 aa) |
| | ENSNLEP00000032935 | Uncharacterized protein. (73 aa) |
| | ACSS1 | Acyl-CoA synthetase short chain family member 1. (655 aa) |
| | DHODH | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (395 aa) |
| | PDHA1 | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (428 aa) |
| | ENSNLEP00000032071 | Uncharacterized protein. (140 aa) |
| | NUDT2 | Nudix hydrolase 2. (147 aa) |
| | ADA | Adenosine deaminase. (405 aa) |
| | ENSNLEP00000031521 | Uncharacterized protein. (491 aa) |
| | ENSNLEP00000030795 | Thymidylate_kin domain-containing protein. (224 aa) |
| | AMPD1 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (780 aa) |
| | ENSNLEP00000030617 | Uncharacterized protein. (128 aa) |
| | ADCY6 | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1055 aa) |
| | ENSNLEP00000030516 | Thymidine kinase. (240 aa) |
| | MAGI3 | Membrane associated guanylate kinase, WW and PDZ domain containing 3. (1481 aa) |
| | DMAC2L | Uncharacterized protein. (251 aa) |
| | NME1-NME2 | Nucleoside diphosphate kinase. (292 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (569 aa) |
| | PRPS2 | Phosphoribosyl pyrophosphate synthetase 2. (312 aa) |
| | LDHC | Lactate dehydrogenase C. (331 aa) |
| | UQCC3 | Ubiquinol-cytochrome c reductase complex assembly factor 3. (93 aa) |
| | ENSNLEP00000029928 | Pribosyltran_N domain-containing protein. (261 aa) |
| | ATP5MF | Uncharacterized protein. (104 aa) |
| | ENSNLEP00000029534 | AIRC domain-containing protein. (373 aa) |
| | AK4-2 | ADK_lid domain-containing protein; Belongs to the adenylate kinase family. (209 aa) |
| | DCTD | dCMP deaminase. (178 aa) |
| | ENSNLEP00000029241 | ADK_lid domain-containing protein; Belongs to the adenylate kinase family. (190 aa) |
| | ENSNLEP00000029228 | Uncharacterized protein; Belongs to the ATPase C chain family. (172 aa) |
| | AK2 | Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. (239 aa) |
| | DLG1 | Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (916 aa) |
| | ENSNLEP00000028474 | ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (118 aa) |
| | GUCY1B1 | Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (643 aa) |
| | ADK | Adenosine kinase. (362 aa) |
| | ELOVL1 | Elongation of very long chain fatty acids protein. (286 aa) |
| | ENSNLEP00000026588 | GMP_synt_C domain-containing protein. (233 aa) |
| | MLYCD | Malonyl-CoA decarboxylase. (493 aa) |
| | ATP5F1B | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (509 aa) |
| | KMO | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (486 aa) |
| | PRPSAP1 | Phosphoribosyl pyrophosphate synthetase associated protein 1. (385 aa) |
| | PRPS1 | Pribosyltran_N domain-containing protein. (318 aa) |
| | NME9 | NME/NM23 family member 9; Belongs to the NDK family. (330 aa) |
| | ENSNLEP00000024528 | Uncharacterized protein. (493 aa) |
| | PRPSAP2 | Phosphoribosyl pyrophosphate synthetase associated protein 2. (369 aa) |
| | G1SBV3_NOMLE | ATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...] (103 aa) |
| | ATP5F1E | ATP synthase F1 subunit epsilon. (51 aa) |
| | PDHA2 | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (388 aa) |
| | HTD2 | Hydroxyacyl-thioester dehydratase type 2. (164 aa) |
| | NMNAT2 | Nicotinamide nucleotide adenylyltransferase 2. (307 aa) |
| | PDHX | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (501 aa) |
| | ATP5MC2 | ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (198 aa) |
| | AK1 | Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. (210 aa) |
| | RRM1 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (792 aa) |
| | HAAO | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (286 aa) |
| | ELOVL6 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa) |
| | CMPK1 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (228 aa) |
| | ADSS1 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (457 aa) |
| | ZBTB49 | Zinc finger and BTB domain containing 49. (766 aa) |
| | NADK2 | NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. (442 aa) |
| | SLC25A13 | Solute carrier family 25 member 13; Belongs to the mitochondrial carrier (TC 2.A.29) family. (676 aa) |
| | ACSBG2 | Acyl-CoA synthetase bubblegum family member 2. (616 aa) |
| | VPS9D1 | VPS9 domain containing 1. (631 aa) |
| | ACSL5 | Acyl-CoA synthetase long chain family member 5. (739 aa) |
| | QPRT | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (291 aa) |
| | APRT | Adenine phosphoribosyltransferase. (180 aa) |
| | GUCD1 | Guanylyl cyclase domain containing 1. (285 aa) |
| | ADCY4 | Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1026 aa) |
| | GARS1 | Glycyl-tRNA synthetase. (739 aa) |
| | ELOVL3 | Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] (270 aa) |
| | NME7 | Nucleoside diphosphate kinase 7; Belongs to the NDK family. (376 aa) |
| | MPC2 | Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (127 aa) |
| | ADCY10 | Adenylate cyclase 10. (1518 aa) |
| | UCK2 | Uridine-cytidine kinase 2. (228 aa) |
| | PPCDC | Phosphopantothenoylcysteine decarboxylase. (221 aa) |
| | TBPL1 | TATA-box binding protein like 1. (186 aa) |
| | ACSL4 | Acyl-CoA synthetase long chain family member 4. (711 aa) |
| | SDHC | Uncharacterized protein. (169 aa) |
| | GUCY2F | Guanylate cyclase. (1127 aa) |
| | NPPC | Natriuretic peptide C. (129 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | SDHB | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (279 aa) |
| | LRGUK | Leucine rich repeats and guanylate kinase domain containing. (826 aa) |
| | AK8 | Adenylate kinase 8; Belongs to the adenylate kinase family. (450 aa) |
| | GCDH | Glutaryl-CoA dehydrogenase. (438 aa) |
| | UCK1 | Uridine-cytidine kinase 1. (281 aa) |
| | AK9 | Adenylate kinase 9. (1911 aa) |
| | ME1 | Malic enzyme. (572 aa) |
| | PARP16 | Poly [ADP-ribose] polymerase. (207 aa) |
| | IDO2 | Indoleamine 2,3-dioxygenase 2. (420 aa) |
| | IDO1 | Indoleamine 2,3-dioxygenase 1. (402 aa) |
| | ELOVL4 | Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (314 aa) |
| | PANK1 | Pantothenate kinase 1. (598 aa) |
| | LOC100591802 | Uncharacterized protein. (558 aa) |
| | PPCS | Phosphopantothenoylcysteine synthetase. (311 aa) |
| | CTPS1 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (591 aa) |
| | PPT1 | Palmitoyl-protein thioesterase 1. (326 aa) |
| | COASY | Coenzyme A synthase. (557 aa) |
| | FLAD1 | FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. (490 aa) |
| | ADCY2 | Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (966 aa) |
| | ACLY | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1103 aa) |
| | ACSL1 | Acyl-CoA synthetase long chain family member 1. (698 aa) |
| | PNP | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa) |
| | NADSYN1 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (706 aa) |
| | CARD11 | Caspase recruitment domain family member 11. (1154 aa) |
| | NPR1 | Guanylate cyclase. (914 aa) |
| | LOC100596171 | Uncharacterized protein. (143 aa) |
| | SLC26A2 | Sulfate transporter; Sulfate transporter. May play a role in endochondral bone formation; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (739 aa) |
| | UCKL1 | Uridine-cytidine kinase; Belongs to the uridine kinase family. (539 aa) |
| | PFAS | Uncharacterized protein. (1108 aa) |
| | GUCY2D | Guanylate cyclase. (1103 aa) |
| | NPPB | Natriuretic peptide B. (134 aa) |
| | AK5 | Adenylate kinase 5; Belongs to the adenylate kinase family. (562 aa) |
| | CTPS2 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (586 aa) |
| | ATP6V0C | V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa) |
| | NMNAT1 | Nicotinamide-nucleotide adenylyltransferase. (260 aa) |
| | KYNU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. (423 aa) |
| | AK3 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (223 aa) |
| | NAMPT | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (475 aa) |
| | PPAT | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (545 aa) |
| | NME3 | Nucleoside diphosphate kinase. (169 aa) |
| | NME5 | NME/NM23 family member 5; Belongs to the NDK family. (212 aa) |
| | ACSBG1 | Acyl-CoA synthetase bubblegum family member 1. (665 aa) |
| | PXDN | Peroxidasin. (1432 aa) |
| | NME4 | Nucleoside diphosphate kinase. (187 aa) |
| | CDA | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa) |
| | PANK2 | Pantothenate kinase 2. (520 aa) |
| | CMPK1-2 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (228 aa) |
| | ATP5MG | ATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...] (103 aa) |
| | PDHB | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa) |
| | DLAT | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (647 aa) |
| | ACAT1 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa) |
| | ATIC | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. (592 aa) |
| | AFMID | Uncharacterized protein. (270 aa) |
| | NADK | Uncharacterized protein. (447 aa) |
| | PANK4 | Pantothenate kinase 4. (693 aa) |
| | PARP9 | Poly(ADP-ribose) polymerase family member 9. (855 aa) |
| | ATP5PD | ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (161 aa) |
| | AK7 | Adenylate kinase 7. (689 aa) |
| | UMPS | Uridine monophosphate synthetase. (481 aa) |
| | ELOVL2 | Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (295 aa) |
| | ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (983 aa) |
| | UPP2 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (363 aa) |
| | ATP5ME | ATP synthase membrane subunit e. (69 aa) |
| | SLC26A1 | Sulfate anion transporter 1; Mediates sulfate transport with high affinity. Mediates oxalate transport. Mediates bicarbonate transport. Does not accept succinate as cosubstrate; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (701 aa) |
| | PTRHD1 | Peptidyl-tRNA hydrolase domain containing 1. (140 aa) |
| | ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1131 aa) |
| | C17orf80 | Chromosome 17 open reading frame 80. (582 aa) |
| | ACACB | Acetyl-CoA carboxylase beta. (2410 aa) |
| | HPRT1 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa) |
| | LOC100581200 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (625 aa) |
| | CASK | Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (912 aa) |
| | PARP10 | Poly [ADP-ribose] polymerase. (1036 aa) |
| | ACACA | Acetyl-CoA carboxylase alpha. (2338 aa) |
| | ATP5MC1 | ATP synthase membrane subunit c locus 1; Belongs to the ATPase C chain family. (136 aa) |
| | NMRK2 | Nicotinamide riboside kinase 2. (235 aa) |
| | AMPD2 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (879 aa) |
| | CAD | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2200 aa) |
| | DIP2A | Disco interacting protein 2 homolog A. (1547 aa) |
| | LOC100600502 | Guanylate cyclase domain-containing protein. (613 aa) |
| | GMPS | Guanine monophosphate synthase. (693 aa) |
| | GUCY2C | Guanylate cyclase. (1073 aa) |
| | GART | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1010 aa) |
| | ATP5PB | ATP synthase peripheral stalk-membrane subunit b. (256 aa) |
| | NPR2 | Guanylate cyclase. (1038 aa) |
| | G1QVV4_NOMLE | Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (292 aa) |
| | NMNAT3 | Nicotinamide-nucleotide adenylyltransferase. (252 aa) |
| | UPP1 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (310 aa) |
| | STOML2 | Stomatin like 2. (361 aa) |
| | ATP6V1A | ATPase H+ transporting V1 subunit A. (617 aa) |
| | PANK3 | Pantothenate kinase 3. (370 aa) |
| | DCAKD | Dephospho-CoA kinase domain containing. (231 aa) |
| | SLC22A13 | Solute carrier family 22 member 13. (551 aa) |
| | ASPDH | Aspartate dehydrogenase domain containing. (283 aa) |
| | ATP5MC3 | ATP synthase membrane subunit c locus 3; Belongs to the ATPase C chain family. (142 aa) |
| | DUT | Deoxyuridine triphosphatase. (237 aa) |
| | SLC5A8 | Solute carrier family 5 member 8; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (611 aa) |
| | GUCY1A1 | Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa) |
| | PPT2 | Palmitoyl-protein thioesterase 2. (308 aa) |
| | IMPDH2 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (514 aa) |
| | TYMS | Thymidylat_synt domain-containing protein. (173 aa) |
| | GUCY1A2 | Uncharacterized protein. (385 aa) |
| | PTGIS | Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa) |
