STRINGSTRING
PANK4 PANK4 ATP5PD ATP5PD UMPS UMPS ELOVL2 ELOVL2 ADCY7 ADCY7 UPP2 UPP2 ATP5ME ATP5ME SLC26A1 SLC26A1 PTRHD1 PTRHD1 ADCY3 ADCY3 C17orf80 C17orf80 ACACB ACACB HPRT1 HPRT1 LOC100581200 LOC100581200 ACACA ACACA ATP5MC1 ATP5MC1 AMPD2 AMPD2 CAD CAD DIP2A DIP2A LOC100600502 LOC100600502 GMPS GMPS GUCY2C GUCY2C GART GART ATP5PB ATP5PB NPR2 NPR2 G1QVV4_NOMLE G1QVV4_NOMLE UPP1 UPP1 STOML2 STOML2 ATP6V1A ATP6V1A PANK3 PANK3 DCAKD DCAKD ATP5MC3 ATP5MC3 GUCY1A1 GUCY1A1 PPT2 PPT2 IMPDH2 IMPDH2 GUCY1A2 GUCY1A2 ATIC ATIC ACAT1 ACAT1 DLAT DLAT PDHB PDHB ATP5MG ATP5MG CMPK1-2 CMPK1-2 PANK2 PANK2 CDA CDA NME4 NME4 ACSBG1 ACSBG1 NME5 NME5 NME3 NME3 PPAT PPAT AK3 AK3 ATP6V0C ATP6V0C CTPS2 CTPS2 AK5 AK5 NPPB NPPB GUCY2D GUCY2D PFAS PFAS UCKL1 UCKL1 SLC26A2 SLC26A2 LOC100596171 LOC100596171 NPR1 NPR1 ACSL1 ACSL1 ACLY ACLY ADCY2 ADCY2 COASY COASY PPT1 PPT1 CTPS1 CTPS1 PPCS PPCS LOC100591802 LOC100591802 PANK1 PANK1 ELOVL4 ELOVL4 AK9 AK9 UCK1 UCK1 GCDH GCDH SDHB SDHB TGFB1 TGFB1 NPPC NPPC GUCY2F GUCY2F SDHC SDHC ACSL4 ACSL4 PPCDC PPCDC UCK2 UCK2 ADCY10 ADCY10 MPC2 MPC2 NME7 NME7 ELOVL3 ELOVL3 ADCY4 ADCY4 GUCD1 GUCD1 APRT APRT ACSL5 ACSL5 VPS9D1 VPS9D1 ACSBG2 ACSBG2 SLC25A13 SLC25A13 ADSS1 ADSS1 CMPK1 CMPK1 ELOVL6 ELOVL6 AK1 AK1 ATP5MC2 ATP5MC2 PDHX PDHX HTD2 HTD2 PDHA2 PDHA2 ATP5F1E ATP5F1E G1SBV3_NOMLE G1SBV3_NOMLE ENSNLEP00000024528 ENSNLEP00000024528 NME9 NME9 ATP5F1B ATP5F1B MLYCD MLYCD ENSNLEP00000026588 ENSNLEP00000026588 ELOVL1 ELOVL1 ADK ADK GUCY1B1 GUCY1B1 ENSNLEP00000028474 ENSNLEP00000028474 AK2 AK2 ENSNLEP00000029228 ENSNLEP00000029228 ENSNLEP00000029241 ENSNLEP00000029241 AK4-2 AK4-2 ENSNLEP00000029534 ENSNLEP00000029534 ATP5MF ATP5MF UQCC3 UQCC3 LDHC LDHC PRKAG2 PRKAG2 NME1-NME2 NME1-NME2 DMAC2L DMAC2L ADCY6 ADCY6 ENSNLEP00000030617 ENSNLEP00000030617 AMPD1 AMPD1 ENSNLEP00000031521 ENSNLEP00000031521 ADA ADA NUDT2 NUDT2 PDHA1 PDHA1 DHODH DHODH ACSS1 ACSS1 ENSNLEP00000032935 ENSNLEP00000032935 ATP5PF ATP5PF ENSNLEP00000033214 ENSNLEP00000033214 ADCY9 ADCY9 PAICS PAICS NDUFB2 NDUFB2 SLC25A16 SLC25A16 ENSNLEP00000034323 ENSNLEP00000034323 ENSNLEP00000034358 ENSNLEP00000034358 RFK RFK ENSNLEP00000034659 ENSNLEP00000034659 IMPDH1 IMPDH1 DCK DCK NME6 NME6 ENSNLEP00000035724 ENSNLEP00000035724 LOC100585501 LOC100585501 ADSS2 ADSS2 ACSS2 ACSS2 ADCY8 ADCY8 ENSNLEP00000038878 ENSNLEP00000038878 ENSNLEP00000038989 ENSNLEP00000038989 ENSNLEP00000040238 ENSNLEP00000040238 IMPDH IMPDH LOC100581732 LOC100581732 ACSL6 ACSL6 ENSNLEP00000040993 ENSNLEP00000040993 ENSNLEP00000041062 ENSNLEP00000041062 ENSNLEP00000041332 ENSNLEP00000041332 ACOT7 ACOT7 ELOVL7 ELOVL7 ATP5MD ATP5MD ADSL ADSL ENSNLEP00000042826 ENSNLEP00000042826 HACD1 HACD1 ATP5F1A ATP5F1A ENSNLEP00000042998 ENSNLEP00000042998 ENSNLEP00000043038 ENSNLEP00000043038 ATP5PO ATP5PO ATP5MPL ATP5MPL ENSNLEP00000043839 ENSNLEP00000043839 ENSNLEP00000043892 ENSNLEP00000043892 UPRT UPRT ENSNLEP00000044316 ENSNLEP00000044316 ENSNLEP00000044748 ENSNLEP00000044748 MTHFD1 MTHFD1 ENSNLEP00000045228 ENSNLEP00000045228 ATP5F1C ATP5F1C PAPSS1 PAPSS1 TECR TECR ADCY1 ADCY1 LOC100582337 LOC100582337 ADCY5 ADCY5 SLC25A1 SLC25A1 AMPD3 AMPD3 ENSNLEP00000048727 ENSNLEP00000048727 PAPSS2 PAPSS2 ELOVL5 ELOVL5 AK4 AK4 DGUOK DGUOK
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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PANK4Pantothenate kinase 4. (693 aa)
ATP5PDATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (161 aa)
UMPSUridine monophosphate synthetase. (481 aa)
ELOVL2Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (295 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (983 aa)
UPP2Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (363 aa)
ATP5MEATP synthase membrane subunit e. (69 aa)
SLC26A1Sulfate anion transporter 1; Mediates sulfate transport with high affinity. Mediates oxalate transport. Mediates bicarbonate transport. Does not accept succinate as cosubstrate; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (701 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1131 aa)
C17orf80Chromosome 17 open reading frame 80. (582 aa)
ACACBAcetyl-CoA carboxylase beta. (2410 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
LOC100581200Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (625 aa)
ACACAAcetyl-CoA carboxylase alpha. (2338 aa)
ATP5MC1ATP synthase membrane subunit c locus 1; Belongs to the ATPase C chain family. (136 aa)
AMPD2AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (879 aa)
CADCarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2200 aa)
DIP2ADisco interacting protein 2 homolog A. (1547 aa)
LOC100600502Guanylate cyclase domain-containing protein. (613 aa)
GMPSGuanine monophosphate synthase. (693 aa)
GUCY2CGuanylate cyclase. (1073 aa)
GARTTrifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1010 aa)
ATP5PBATP synthase peripheral stalk-membrane subunit b. (256 aa)
NPR2Guanylate cyclase. (1038 aa)
G1QVV4_NOMLEGuanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (292 aa)
UPP1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (310 aa)
STOML2Stomatin like 2. (361 aa)
ATP6V1AATPase H+ transporting V1 subunit A. (617 aa)
PANK3Pantothenate kinase 3. (370 aa)
DCAKDDephospho-CoA kinase domain containing. (231 aa)
ATP5MC3ATP synthase membrane subunit c locus 3; Belongs to the ATPase C chain family. (142 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
PPT2Palmitoyl-protein thioesterase 2. (308 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (514 aa)
GUCY1A2Uncharacterized protein. (385 aa)
ATIC5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. (592 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (647 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
ATP5MGATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...] (103 aa)
CMPK1-2UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (228 aa)
PANK2Pantothenate kinase 2. (520 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa)
NME4Nucleoside diphosphate kinase. (187 aa)
ACSBG1Acyl-CoA synthetase bubblegum family member 1. (665 aa)
NME5NME/NM23 family member 5; Belongs to the NDK family. (212 aa)
NME3Nucleoside diphosphate kinase. (169 aa)
PPATAmidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (545 aa)
AK3GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (223 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
CTPS2CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (586 aa)
AK5Adenylate kinase 5; Belongs to the adenylate kinase family. (562 aa)
NPPBNatriuretic peptide B. (134 aa)
GUCY2DGuanylate cyclase. (1103 aa)
PFASUncharacterized protein. (1108 aa)
UCKL1Uridine-cytidine kinase; Belongs to the uridine kinase family. (539 aa)
SLC26A2Sulfate transporter; Sulfate transporter. May play a role in endochondral bone formation; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (739 aa)
LOC100596171Uncharacterized protein. (143 aa)
NPR1Guanylate cyclase. (914 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (698 aa)
ACLYATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1103 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (966 aa)
COASYCoenzyme A synthase. (557 aa)
PPT1Palmitoyl-protein thioesterase 1. (326 aa)
CTPS1CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (591 aa)
PPCSPhosphopantothenoylcysteine synthetase. (311 aa)
LOC100591802Uncharacterized protein. (558 aa)
PANK1Pantothenate kinase 1. (598 aa)
ELOVL4Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (314 aa)
AK9Adenylate kinase 9. (1911 aa)
UCK1Uridine-cytidine kinase 1. (281 aa)
GCDHGlutaryl-CoA dehydrogenase. (438 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (279 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
NPPCNatriuretic peptide C. (129 aa)
GUCY2FGuanylate cyclase. (1127 aa)
SDHCUncharacterized protein. (169 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (711 aa)
PPCDCPhosphopantothenoylcysteine decarboxylase. (221 aa)
UCK2Uridine-cytidine kinase 2. (228 aa)
ADCY10Adenylate cyclase 10. (1518 aa)
MPC2Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (127 aa)
NME7Nucleoside diphosphate kinase 7; Belongs to the NDK family. (376 aa)
ELOVL3Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] (270 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1026 aa)
GUCD1Guanylyl cyclase domain containing 1. (285 aa)
APRTAdenine phosphoribosyltransferase. (180 aa)
ACSL5Acyl-CoA synthetase long chain family member 5. (739 aa)
VPS9D1VPS9 domain containing 1. (631 aa)
ACSBG2Acyl-CoA synthetase bubblegum family member 2. (616 aa)
SLC25A13Solute carrier family 25 member 13; Belongs to the mitochondrial carrier (TC 2.A.29) family. (676 aa)
ADSS1Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (457 aa)
CMPK1UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (228 aa)
ELOVL6Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa)
AK1Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. (210 aa)
ATP5MC2ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (198 aa)
PDHXDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (501 aa)
HTD2Hydroxyacyl-thioester dehydratase type 2. (164 aa)
PDHA2Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (388 aa)
ATP5F1EATP synthase F1 subunit epsilon. (51 aa)
G1SBV3_NOMLEATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...] (103 aa)
ENSNLEP00000024528Uncharacterized protein. (493 aa)
NME9NME/NM23 family member 9; Belongs to the NDK family. (330 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (509 aa)
MLYCDMalonyl-CoA decarboxylase. (493 aa)
ENSNLEP00000026588GMP_synt_C domain-containing protein. (233 aa)
ELOVL1Elongation of very long chain fatty acids protein. (286 aa)
ADKAdenosine kinase. (362 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (643 aa)
ENSNLEP00000028474ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (118 aa)
AK2Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. (239 aa)
ENSNLEP00000029228Uncharacterized protein; Belongs to the ATPase C chain family. (172 aa)
ENSNLEP00000029241ADK_lid domain-containing protein; Belongs to the adenylate kinase family. (190 aa)
AK4-2ADK_lid domain-containing protein; Belongs to the adenylate kinase family. (209 aa)
ENSNLEP00000029534AIRC domain-containing protein. (373 aa)
ATP5MFUncharacterized protein. (104 aa)
UQCC3Ubiquinol-cytochrome c reductase complex assembly factor 3. (93 aa)
LDHCLactate dehydrogenase C. (331 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (569 aa)
NME1-NME2Nucleoside diphosphate kinase. (292 aa)
DMAC2LUncharacterized protein. (251 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1055 aa)
ENSNLEP00000030617Uncharacterized protein. (128 aa)
AMPD1AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (780 aa)
ENSNLEP00000031521Uncharacterized protein. (491 aa)
ADAAdenosine deaminase. (405 aa)
NUDT2Nudix hydrolase 2. (147 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (428 aa)
DHODHDihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (395 aa)
ACSS1Acyl-CoA synthetase short chain family member 1. (655 aa)
ENSNLEP00000032935Uncharacterized protein. (73 aa)
ATP5PFATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (119 aa)
ENSNLEP00000033214Uncharacterized protein. (72 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1310 aa)
PAICSAIRC domain-containing protein. (451 aa)
NDUFB2NADH:ubiquinone oxidoreductase subunit B2. (105 aa)
SLC25A16Solute carrier family 25 member 16; Belongs to the mitochondrial carrier (TC 2.A.29) family. (331 aa)
ENSNLEP00000034323S5A_REDUCTASE domain-containing protein. (264 aa)
ENSNLEP00000034358Uncharacterized protein. (268 aa)
RFKRiboflavin kinase. (162 aa)
ENSNLEP00000034659Uncharacterized protein. (407 aa)
IMPDH1CBS domain-containing protein. (487 aa)
DCKdNK domain-containing protein. (317 aa)
NME6Nucleoside diphosphate kinase. (194 aa)
ENSNLEP00000035724Uncharacterized protein. (122 aa)
LOC100585501IMPDH domain-containing protein. (529 aa)
ADSS2Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (458 aa)
ACSS2Acyl-CoA synthetase short chain family member 2. (714 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
ENSNLEP00000038878ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (127 aa)
ENSNLEP00000038989Uncharacterized protein. (64 aa)
ENSNLEP00000040238Uncharacterized protein. (384 aa)
IMPDHInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (516 aa)
LOC100581732Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (581 aa)
ACSL6AMP-binding domain-containing protein. (700 aa)
ENSNLEP00000040993Uncharacterized protein. (521 aa)
ENSNLEP00000041062Uncharacterized protein. (151 aa)
ENSNLEP00000041332Uncharacterized protein. (126 aa)
ACOT7Uncharacterized protein. (472 aa)
ELOVL7Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (281 aa)
ATP5MDATP synthase membrane subunit DAPIT. (58 aa)
ADSLAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (498 aa)
ENSNLEP00000042826Uncharacterized protein. (217 aa)
HACD1Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (288 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (545 aa)
ENSNLEP00000042998Uncharacterized protein. (354 aa)
ENSNLEP00000043038Uncharacterized protein. (67 aa)
ATP5POUncharacterized protein. (213 aa)
ATP5MPLUncharacterized protein. (98 aa)
ENSNLEP00000043839Uncharacterized protein. (93 aa)
ENSNLEP00000043892Uncharacterized protein. (162 aa)
UPRTUncharacterized protein. (173 aa)
ENSNLEP00000044316Uncharacterized protein; Belongs to the adenylate kinase family. (134 aa)
ENSNLEP00000044748Uncharacterized protein. (374 aa)
MTHFD1Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (990 aa)
ENSNLEP00000045228ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (141 aa)
ATP5F1CATP synthase subunit gamma. (325 aa)
PAPSS13'-phosphoadenosine 5'-phosphosulfate synthase 1. (624 aa)
TECRS5A_REDUCTASE domain-containing protein. (319 aa)
ADCY1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (338 aa)
LOC100582337Nucleoside diphosphate kinase. (147 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1262 aa)
SLC25A1Solute carrier family 25 member 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (259 aa)
AMPD3AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (776 aa)
ENSNLEP00000048727Uncharacterized protein. (283 aa)
PAPSS23'-phosphoadenosine 5'-phosphosulfate synthase 2. (619 aa)
ELOVL5Elongation of very long chain fatty acids protein. (326 aa)
AK4Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (223 aa)
DGUOKDeoxyguanosine kinase. (277 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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